Background: Chronic hepatitis C is the most common cause of chronic liver disease and cirrhosis. Egypt is the highest affected country with a prevalence of 22%. In children, seroprevalence of HCV is 0.2% in children less than 11 years of age and 0.4% in children equal and more than 11 years of age. Aim of the work: The purpose of this study was to assess the value of 1H MRS and DW-MRI as non invasive tool in evaluation of activity and fibrosis of hepatic parenchyma in asymptomatic children with chronic hepatitis C. Subjects and Methods: Across-section study was conducted over a period of two years, included thirty children of asymptomatic chronic hepatitis C virus infection (mean age + SD 14.1+2.8 years) and twenty healthy children as controls were included. Abdominal ultrasonography, Percutaneous liver biopsy, MRS and DW-MRI were done to all cases. Results: The results showed HCV infection was more common in our males (83.3%). The results of METAVIR grades showed 29 cases (99.9%) had activity while 17 cases (56.4%) had fibrosis. The results of MRS& DW-MRI showed significant differences between cases and controls and positive correlations between of the results of 1H MRS with the results of liver biopsy (METAVIR Grades and METAVIR Stages). Conclusion: Early diagnosis of asymptomatic chronic hepatitis C is essential to prevent or delay end stage chronic parenchymal liver disease. 1H MRS may be a potential non-invasive helpful diagnostic tool in assessment the staging andfibrosis of asymptomatic chronic hepatitis C. As the increased of its metabolites were correlated with histopathological changes. DW-MRI can be considered an effective predictor in assessment of activity in chronic hepatitis C.

Background: Chronic hepatitis C is the most common cause of chronic liver disease and cirrhosis. Egypt is the highest affected country with a prevalence of 22%. In children, seroprevalence of HCV is 0.2% in children less than 11 years of age and 0.4% in children equal and more than 11 years of age. Aim of the work: The purpose of this study was to assess the value of 1H MRS and DW-MRI as non invasive tool in evaluation of activity and fibrosis of hepatic parenchyma in asymptomatic children with chronic hepatitis C. Subjects and Methods: Across-section study was conducted over a period of two years, included thirty children of asymptomatic chronic hepatitis C virus infection (mean age + SD 14.1+2.8 years) and twenty healthy children as controls were included. Abdominal ultrasonography, Percutaneous liver biopsy, MRS and DW-MRI were done to all cases. Results: The results showed HCV infection was more common in our males (83.3%). The results of METAVIR grades showed 29 cases (99.9%) had activity while 17 cases (56.4%) had fibrosis. The results of MRS& DW-MRI showed significant differences between cases and controls and positive correlations between of the results of 1H MRS with the results of liver biopsy (METAVIR Grades and METAVIR Stages). Conclusion: Early diagnosis of asymptomatic chronic hepatitis C is essential to prevent or delay end stage chronic parenchymal liver disease. 1H MRS may be a potential non-invasive helpful diagnostic tool in assessment the staging andfibrosis of asymptomatic chronic hepatitis C. As the increased of its metabolites were correlated with histopathological changes. DW-MRI can be considered an effective predictor in assessment of activity in chronic hepatitis C.

Background: Chronic hepatitis C is the most common cause of chronic liver disease and cirrhosis. Egypt is the highest affected country with a prevalence of 22%. In children, seroprevalence of HCV is 0.2% in children less than 11 years of age and 0.4% in children equal and more than 11 years of age. Aim of the work: The purpose of this study was to assess the value of 1H MRS and DW-MRI as non invasive tool in evaluation of activity and fibrosis of hepatic parenchyma in asymptomatic children with chronic hepatitis C. Subjects and Methods: Across-section study was conducted over a period of two years, included thirty children of asymptomatic chronic hepatitis C virus infection (mean age + SD 14.1+2.8 years) and twenty healthy children as controls were included. Abdominal ultrasonography, Percutaneous liver biopsy, MRS and DW-MRI were done to all cases. Results: The results showed HCV infection was more common in our males (83.3%). The results of METAVIR grades showed 29 cases (99.9%) had activity while 17 cases (56.4%) had fibrosis. The results of MRS& DW-MRI showed significant differences between cases and controls and positive correlations between of the results of 1H MRS with the results of liver biopsy (METAVIR Grades and METAVIR Stages). Conclusion: Early diagnosis of asymptomatic chronic hepatitis C is essential to prevent or delay end stage chronic parenchymal liver disease. 1H MRS may be a potential non-invasive helpful diagnostic tool in assessment the staging andfibrosis of asymptomatic chronic hepatitis C. As the increased of its metabolites were correlated with histopathological changes. DW-MRI can be considered an effective predictor in assessment of activity in chronic hepatitis C.

Background: Chronic hepatitis C is the most common cause of chronic liver disease and cirrhosis. Egypt is the highest affected country with a prevalence of 22%. In children, seroprevalence of HCV is 0.2% in children less than 11 years of age and 0.4% in children equal and more than 11 years of age. Aim of the work: The purpose of this study was to assess the value of 1H MRS and DW-MRI as non invasive tool in evaluation of activity and fibrosis of hepatic parenchyma in asymptomatic children with chronic hepatitis C. Subjects and Methods: Across-section study was conducted over a period of two years, included thirty children of asymptomatic chronic hepatitis C virus infection (mean age + SD 14.1+2.8 years) and twenty healthy children as controls were included. Abdominal ultrasonography, Percutaneous liver biopsy, MRS and DW-MRI were done to all cases. Results: The results showed HCV infection was more common in our males (83.3%). The results of METAVIR grades showed 29 cases (99.9%) had activity while 17 cases (56.4%) had fibrosis. The results of MRS& DW-MRI showed significant differences between cases and controls and positive correlations between of the results of 1H MRS with the results of liver biopsy (METAVIR Grades and METAVIR Stages). Conclusion: Early diagnosis of asymptomatic chronic hepatitis C is essential to prevent or delay end stage chronic parenchymal liver disease. 1H MRS may be a potential non-invasive helpful diagnostic tool in assessment the staging andfibrosis of asymptomatic chronic hepatitis C. As the increased of its metabolites were correlated with histopathological changes. DW-MRI can be considered an effective predictor in assessment of activity in chronic hepatitis C.

Background: Chronic hepatitis C is the most common cause of chronic liver disease and cirrhosis. Egypt is the highest affected country with a prevalence of 22%. In children, seroprevalence of HCV is 0.2% in children less than 11 years of age and 0.4% in children equal and more than 11 years of age. Aim of the work: The purpose of this study was to assess the value of 1H MRS and DW-MRI as non invasive tool in evaluation of activity and fibrosis of hepatic parenchyma in asymptomatic children with chronic hepatitis C. Subjects and Methods: Across-section study was conducted over a period of two years, included thirty children of asymptomatic chronic hepatitis C virus infection (mean age + SD 14.1+2.8 years) and twenty healthy children as controls were included. Abdominal ultrasonography, Percutaneous liver biopsy, MRS and DW-MRI were done to all cases. Results: The results showed HCV infection was more common in our males (83.3%). The results of METAVIR grades showed 29 cases (99.9%) had activity while 17 cases (56.4%) had fibrosis. The results of MRS& DW-MRI showed significant differences between cases and controls and positive correlations between of the results of 1H MRS with the results of liver biopsy (METAVIR Grades and METAVIR Stages). Conclusion: Early diagnosis of asymptomatic chronic hepatitis C is essential to prevent or delay end stage chronic parenchymal liver disease. 1H MRS may be a potential non-invasive helpful diagnostic tool in assessment the staging andfibrosis of asymptomatic chronic hepatitis C. As the increased of its metabolites were correlated with histopathological changes. DW-MRI can be considered an effective predictor in assessment of activity in chronic hepatitis C.

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Introduction: Septal deviation is usually associated with compensatory hypertrophy of the contralateral inferior nasal turbinate. The current treatment of septal deviation is septoplasty but there is controversy about surgery for the hypertrophied inferior turbinate because of evidence that degree of satisfaction of patients who undergo septoplasty alone is similar to those who undergo septoplasty and turbinectomy. Aim of work: to determine the effect of septal surgery alone in patients with C shaped deviated nasal septum on the hypertrophied inferior turbinate radiologically and functionally. Patients and Methods: This prospective study was done on 40 patients during the period from (January 2014 to June 2015) complaining of bilateral nasal obstruction caused by C shaped septal deviation and inferior turbinate hypertrophy, their age ranged from 19-35 year. All of them underwent septoplasty alone without turbinate surgery. The volume of the hypertrophied inferior turbinate was measured before and after surgery by CT scan of paranasal sinuses coronal and axial planes. Results: According to the results obtained from this study septoplasty alone significantly decreased the mean volume of hypertrophied inferior turbinate by 0.825mm3 (p value 0.005). Conclusion: The inferior turbinate hypertrophy reduced in size after septoplasty without turbinate surgery.