The hydro solvothermal method was employed to synthesize nano porous aluminum metal organic framework (Al-MOF) nanoparticles (NPs), which were utilized as a matrix for the pharmaceutical delivery of Edaravone (Ed). The drug encapsulation efficiency (EE) and loading capacity (LC) indicate the potential of Al metal organic framework NPs as effective drug delivery vehicles. The structural and functional properties of both the Al metal organic framework NPs and Ed-loaded Al metal organic framework NPs (Ed@Al-MOF) were characterized using several techniques, including ultraviolet-visible (UV-Vis) spectroscopy, Transmission Electron Microscopy (TEM) for morphological analysis, X-ray diffractometry (XRD), and Fourier-transform infrared (FTIR) spectroscopy. Additionally, the thermal stability of the Ed@Al metal organic framework NPs was evaluated through thermogravimetric analysis (TGA). These promising results underscore the potential of Al metal organic framework NPs as a viable platform for drug delivery, necessitating further investigations to confirm the applicability of Ed@Al metal organic framework NPs in therapeutic contexts.

The reuse of expired drugs has become a challenge in maintaining environmental cleanliness and achieving economic benefits. In this report, two expired drugs, moxifloxacin and norfloxacin, were used as inhibitors for copper corrosion in 3.5 % NaCl solution at different temperatures using several experimental approaches including chemical, electrochemical and spectroscopic techniques. The interaction of these two molecules on the copper surface was also inspected using different adsorption models. Using a dose of 500 mg L-1 of these drugs at 298 K, maximum inhibition efficiencies (IE) of 88.7 and 85.2 % were estimated from the potentiodynamic polarization technique for Mox and Nor, respectively., confirming that they can be considered as promising and effective inhibitors. The IE values were enhanced with increasing drug doses and reduced with rising temperature. The higher IE is due to the strong adsorption of these molecules on the copper surface, which is physical in nature and follows the Langmuir adsorption isotherm. This is due to their unique chemical structures, as they contain a number of functional groups. Polarization experiments confirmed that the drugs were tuned to behave as mixed-type inhibitors with an anodic predominance. All thermodynamic and kinetic parameters were calculated and discussed in details , and the inhibition mechanism was proposed. All experimental results obtained by different techniques were in agreement with each other.

In this study, binder-free CoS₂–reduced graphene oxide (rGO) nanocomposites (NCs) were deposited on Cu₂O nanosheets via one-step electrodeposition. rGO was obtained from carbon dioxide electroreduction during CoS₂ deposition. CoS₂–rGO@Cu₂O heterostructure electrodes were deposited for varying electrodeposition times, and their performance in nonenzymatic glucose sensing in 0.1 M NaOH was determined. Raman spectroscopy and X-ray photoelectron spectroscopy (XPS) verified the formation of rGO in all heterostructure electrodes. Various interfacial bonding states between Cu₂O nanosheets and CoS₂–rGO NCs were detected, indicating improved interfacial synergy between the heterostructure layers. Moreover, the phase transformation from CoS to CoS₂ occurred as the electrodeposition time was increased from 10 to 30 min. The CoS₂–rGO@Cu₂O heterostructure electrodes electrodeposited for 20 min were considered optimum for enzyme-free glucose sensing. The sensors exhibited a sensitivity of 635.94 μA·mM⁻¹·cm⁻² for glucose oxidation with a limit of detection of 17 μM in a wide linear detection range of 100–3000 μM. All the CoS₂–rGO@Cu₂O heterostructure electrodes exhibited enhanced selectivity to glucose oxidation in the presence of other interfering species and long-term stability for 3000 s.