Skip to main content

Protective effect of oxytocin against bone loss in a female rat model of osteoporosis

Research Abstract
NULL
Research Authors
Hoda M Moghazy 1, Aida Abdeen Mahmoud 2, Hala M Elbadre 3, Hekmat Osman Abdel Aziz 4
Research Department
Research Journal
Reports of Biochemistry and Molecular Biology
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
NULL
Research Year
2020

Posterior Vertebral Column Resection (PVCR) in Early Onset Spinal Deformities (EOSD)

Research Abstract
NULL
Research Authors
Mohammad El-Sharkawi, Wael Koptan, Amer Elkott, Hamdy Tammam, Wael Gad, Nariman Aboloyoun, Ahmed Shawky
Research Journal

Global Spine Journal
Research Pages
NULL
Research Publisher
SAGE Publications Ltd
Research Rank
3
Research Vol
Vol 6, Issue 1_suppl, 2016
Research Website
https://journals.sagepub.com/doi/10.1055/s-0036-1583058
Research Year
2016

Posterior Vertebral Column Resection (PVCR) in Early Onset Spinal Deformities (EOSD)

Research Abstract
NULL
Research Authors
Mohammad El-Sharkawi, Wael Koptan, Amer Elkott, Hamdy Tammam, Wael Gad, Nariman Aboloyoun, Ahmed Shawky
Research Journal

Global Spine Journal
Research Pages
NULL
Research Publisher
SAGE Publications Ltd
Research Rank
3
Research Vol
Vol 6, Issue 1_suppl, 2016
Research Website
https://journals.sagepub.com/doi/10.1055/s-0036-1583058
Research Year
2016

Posterior Vertebral Column Resection (PVCR) in Early Onset Spinal Deformities (EOSD)

Research Abstract
NULL
Research Authors
Mohammad El-Sharkawi, Wael Koptan, Amer Elkott, Hamdy Tammam, Wael Gad, Nariman Aboloyoun, Ahmed Shawky
Research Journal

Global Spine Journal
Research Pages
NULL
Research Publisher
SAGE Publications Ltd
Research Rank
3
Research Vol
Vol 6, Issue 1_suppl, 2016
Research Website
https://journals.sagepub.com/doi/10.1055/s-0036-1583058
Research Year
2016

Junctional Kyphosis after Long Segment Fusion

Research Abstract
Introduction The incidence of junctional kyphosis (JK) varies in the literature from 7% to 40%. We here present our experience with JK. The aim of this work is investigate the incidence of JK after long spinal segment fusion, to identify the underlying factors leading to its development, and to discuss treatment outcome. Patients and Methods This combined retrospective/prospective cohort study included sixty-four consecutive patients (40 women and 24 men) with a mean age of 20.7 years, who underwent long segment spinal fusion (≥ 5 vertebrae) for treatment of spinal deformity. The average length of follow-up was 2 years. Risk factors analyzed included patients’ factors, surgical factors, and radiographical parameters such as thoracic kyphosis (TK), lumbar lordosis (LL), sagittal vertical axis, pelvic tilt, and pelvic incidence. Results Radiological JK occurred in 14 patients (22%). Ten cases were proximal junctional kyphosis (PJK), two cases were intercalary junctional kyphosis (IJK), and two cases were distal Junctional Kyphosis (DJK). Only seven patients (50%) out of the 14 with JK were symptomatic. Six cases have undergone revision surgery. In nine cases, the original deformity was kyphosis (1 Ankylosing spondylitisS, 1 post-tuberculous, 3 Sheuermann's kyphosis, 4 congenital kyphosis). The other 5 cases were scoliosis (3 idiopathic and 2 congenital). Preoperative TK more than 40 ° was associated with PJK. In all cases PI, PT, SS, SVA were within normal range, but it was noticed that SVA had negative values in 5 cases. LIV in the dorsolumbar junction was associated with DJK. Conclusion Pre-existing TK more than 40°was identified as an independent risk factor. Negative sagittal balance may be a risk factor for PJK. A surgical strategy to minimize Junctional kyphosis may include careful preoperative planning for reconstructions with a goal of optimal postoperative alignment.
Research Authors
Mohammad El-Sharkawi, Wael Gad, Amer Elkott, Hamdy Tammam, Mohamed El-Meshtawy
Research Journal
Global Spine Journal
Research Pages
NULL
Research Publisher
SAGE Publications Ltd
Research Rank
3
Research Vol
Vol 6, Issue 1_suppl, 2016
Research Website
https://journals.sagepub.com/doi/10.1055/s-0036-1582818
Research Year
2016

Junctional Kyphosis after Long Segment Fusion

Research Abstract
Introduction The incidence of junctional kyphosis (JK) varies in the literature from 7% to 40%. We here present our experience with JK. The aim of this work is investigate the incidence of JK after long spinal segment fusion, to identify the underlying factors leading to its development, and to discuss treatment outcome. Patients and Methods This combined retrospective/prospective cohort study included sixty-four consecutive patients (40 women and 24 men) with a mean age of 20.7 years, who underwent long segment spinal fusion (≥ 5 vertebrae) for treatment of spinal deformity. The average length of follow-up was 2 years. Risk factors analyzed included patients’ factors, surgical factors, and radiographical parameters such as thoracic kyphosis (TK), lumbar lordosis (LL), sagittal vertical axis, pelvic tilt, and pelvic incidence. Results Radiological JK occurred in 14 patients (22%). Ten cases were proximal junctional kyphosis (PJK), two cases were intercalary junctional kyphosis (IJK), and two cases were distal Junctional Kyphosis (DJK). Only seven patients (50%) out of the 14 with JK were symptomatic. Six cases have undergone revision surgery. In nine cases, the original deformity was kyphosis (1 Ankylosing spondylitisS, 1 post-tuberculous, 3 Sheuermann's kyphosis, 4 congenital kyphosis). The other 5 cases were scoliosis (3 idiopathic and 2 congenital). Preoperative TK more than 40 ° was associated with PJK. In all cases PI, PT, SS, SVA were within normal range, but it was noticed that SVA had negative values in 5 cases. LIV in the dorsolumbar junction was associated with DJK. Conclusion Pre-existing TK more than 40°was identified as an independent risk factor. Negative sagittal balance may be a risk factor for PJK. A surgical strategy to minimize Junctional kyphosis may include careful preoperative planning for reconstructions with a goal of optimal postoperative alignment.
Research Authors
Mohammad El-Sharkawi, Wael Gad, Amer Elkott, Hamdy Tammam, Mohamed El-Meshtawy
Research Journal
Global Spine Journal
Research Pages
NULL
Research Publisher
SAGE Publications Ltd
Research Rank
3
Research Vol
Vol 6, Issue 1_suppl, 2016
Research Website
https://journals.sagepub.com/doi/10.1055/s-0036-1582818
Research Year
2016

Anterior Cervical Discectomy and Fusion Using an “Oversized” PEEK Cage: Radiological and Clinical Outcome

Research Abstract
Introduction There has been controversial data about the effect of cage size on radiological and clinical outcome of anterior cervical discectomy and fusion (ACDF). Oversized cages have been linked to higher incidence of non-union, adjacent segment disease, and unfavorable clinical outcomes. The aim of this work is to evaluate the effect of an oversized PEEK cage on the radiological and clinical outcomes in ACDF. Patients and Methods Between January 2012 to July 2014, 57 patients (29 single level, 15 double levels, 8 three levels, 5 four levels) underwent ACDF using a stand-alone oversized PEEK cages. They were 35 males and 22 females with mean age 56 ± 13.5 years. The minimum follow up period is one year. The following parameters were measured preoperatively, postoperatively and at final follow up: cervical lordosis (in degrees), disc height (in mm), motion at operated level (in degrees), radiological ASD (present or not) and VAS for neck pain, VAS for arm pain. All complications were as well recorded. Results The mean cervical lordosis changed from 25°±5.5 postoperative to 7°±4.5 at final follow up. The mean disc height was 5± 2 mm preop, 7 ± 1.5 mm postop and 6 ± 1 mm at final follow up. Residual motion at operated level was observed at 1 year follow up X-rays in 2 patients (one double level and one 3-level) with average 5°. None of them had neck pain and no revision was required. In the postoperative X-rays, the suprajacent level was always observed to be slightly narrowed; this narrowing gradually diminished during the follow up. Radiological ASD developed in 9 patients (16%), all of them remained to date asymptomatic. The average improvement in VAS for neck pain was 27%±8.5 and the average improvement in VAS for arm pain was 33%±9.5. At the final follow up, fusion was achieved in 55 patients (96%) and clinical outcome was excellent. Radiological loss of the postoperative disc height and cervical lordosis and development of radiological ASD did not correlate to poor clinical outcome. No single case of cage dislodgement was observed in this series. Conclusion The use of a stand-alone oversized PEEK cage in ACDF seems to minimize the incidence of cage dislodgment even in multiple levels ACDF. Despite some radiological settlement and loss of cervical lordosis, an excellent clinical outcome was maintained.
Research Authors
Mohammad El-Sharkawi, Wael Gad
Research Journal

Global Spine Journal
Research Pages
age(s): s-0036-1582842-s-0036-1582842
Research Publisher
SAGE Publications Ltd
Research Rank
3
Research Vol
Vol 6, Issue 1_suppl, 2016
Research Website
https://journals.sagepub.com/doi/abs/10.1055/s-0036-1582842
Research Year
2017

The Extraforaminal Approach for the Management of Far Lateral Lumbar Disc Herniation

Research Abstract
Background Data: Far lateral lumbar disc herniation accounts for 1-12% of all lumbar disc herniations. Every aspect of management of this unique type of lumbar disc herniation is challenging for spine surgeons, and no consensus has been reached for the best surgical approach and technique to use. Purpose: The purpose of this study is to evaluate the extraforaminal approach, which is a less invasive approach, for the treatment of far lateral lumbar disc herniation. Study Design: A prospective case series. Patients and Methods: Of 501 lumbar disc prolapse patients treated surgically in our department between September 2013 and August 2015, 15 patients presented with far lateral lumbar disc herniation. These 15 patients (11 males and 4 females, mean age 46.80 ± 8.08 years) were treated surgically using the extraforaminal approach and were prospectively followed for 1 year. The study was approved by the Institution Ethical Committee, and all patients signed an informed consent form. Clinical and functional outcomes were assessed using VAS and ODI scores and MacNab’s criteria. Follow-up MRI was performed at 1 year. Results: Far lateral lumbar disc herniation accounted for 3% of all lumbar disc herniation patients treated surgically in our department. The mean back pain VAS score improved from 6.46 preoperatively to 1.06 at the 1-year follow-up evaluation (P=0.001). The mean leg pain VAS score improved from 7.40 preoperatively to 1.06 at the 1-year follow-up evaluation (P=0.001). The mean ODI score improved from 30.20 preoperatively to 2.80 at the 1-year follow-up evaluation (P=0.001). According to MacNab’s criteria, 12 patients (80%) had excellent outcomes, 3 (20%) had good outcomes, and no patients showed fair or poor outcomes at the final follow-up evaluation at 1 year. Conclusion: The extraforaminal approach seems to be a safe, less traumatic and less destabilizing approach for managing far lateral lumbar disc herniation and can lead to a better outcome than traditional approaches. (2017ESJ129)
Research Authors
Al Moataz El-Sabrout*, Mohammad El-Sharkawi*, Mohamed
El-Meshtawy*, Romany Zaki
Research Journal
Egyptian Spine Journal
Research Pages
15-22
Research Publisher
Egyptian Spine Association
Research Rank
2
Research Vol
Volume 22, Issue 1
Research Website
https://esj.journals.ekb.eg/article_5633.html
Research Year
2017

The Extraforaminal Approach for the Management of Far Lateral Lumbar Disc Herniation

Research Abstract
Background Data: Far lateral lumbar disc herniation accounts for 1-12% of all lumbar disc herniations. Every aspect of management of this unique type of lumbar disc herniation is challenging for spine surgeons, and no consensus has been reached for the best surgical approach and technique to use. Purpose: The purpose of this study is to evaluate the extraforaminal approach, which is a less invasive approach, for the treatment of far lateral lumbar disc herniation. Study Design: A prospective case series. Patients and Methods: Of 501 lumbar disc prolapse patients treated surgically in our department between September 2013 and August 2015, 15 patients presented with far lateral lumbar disc herniation. These 15 patients (11 males and 4 females, mean age 46.80 ± 8.08 years) were treated surgically using the extraforaminal approach and were prospectively followed for 1 year. The study was approved by the Institution Ethical Committee, and all patients signed an informed consent form. Clinical and functional outcomes were assessed using VAS and ODI scores and MacNab’s criteria. Follow-up MRI was performed at 1 year. Results: Far lateral lumbar disc herniation accounted for 3% of all lumbar disc herniation patients treated surgically in our department. The mean back pain VAS score improved from 6.46 preoperatively to 1.06 at the 1-year follow-up evaluation (P=0.001). The mean leg pain VAS score improved from 7.40 preoperatively to 1.06 at the 1-year follow-up evaluation (P=0.001). The mean ODI score improved from 30.20 preoperatively to 2.80 at the 1-year follow-up evaluation (P=0.001). According to MacNab’s criteria, 12 patients (80%) had excellent outcomes, 3 (20%) had good outcomes, and no patients showed fair or poor outcomes at the final follow-up evaluation at 1 year. Conclusion: The extraforaminal approach seems to be a safe, less traumatic and less destabilizing approach for managing far lateral lumbar disc herniation and can lead to a better outcome than traditional approaches. (2017ESJ129)
Research Authors
Al Moataz El-Sabrout*, Mohammad El-Sharkawi*, Mohamed
El-Meshtawy*, Romany Zaki
Research Journal
Egyptian Spine Journal
Research Pages
15-22
Research Publisher
Egyptian Spine Association
Research Rank
2
Research Vol
Volume 22, Issue 1
Research Website
https://esj.journals.ekb.eg/article_5633.html
Research Year
2017

The Extraforaminal Approach for the Management of Far Lateral Lumbar Disc Herniation

Research Abstract
Background Data: Far lateral lumbar disc herniation accounts for 1-12% of all lumbar disc herniations. Every aspect of management of this unique type of lumbar disc herniation is challenging for spine surgeons, and no consensus has been reached for the best surgical approach and technique to use. Purpose: The purpose of this study is to evaluate the extraforaminal approach, which is a less invasive approach, for the treatment of far lateral lumbar disc herniation. Study Design: A prospective case series. Patients and Methods: Of 501 lumbar disc prolapse patients treated surgically in our department between September 2013 and August 2015, 15 patients presented with far lateral lumbar disc herniation. These 15 patients (11 males and 4 females, mean age 46.80 ± 8.08 years) were treated surgically using the extraforaminal approach and were prospectively followed for 1 year. The study was approved by the Institution Ethical Committee, and all patients signed an informed consent form. Clinical and functional outcomes were assessed using VAS and ODI scores and MacNab’s criteria. Follow-up MRI was performed at 1 year. Results: Far lateral lumbar disc herniation accounted for 3% of all lumbar disc herniation patients treated surgically in our department. The mean back pain VAS score improved from 6.46 preoperatively to 1.06 at the 1-year follow-up evaluation (P=0.001). The mean leg pain VAS score improved from 7.40 preoperatively to 1.06 at the 1-year follow-up evaluation (P=0.001). The mean ODI score improved from 30.20 preoperatively to 2.80 at the 1-year follow-up evaluation (P=0.001). According to MacNab’s criteria, 12 patients (80%) had excellent outcomes, 3 (20%) had good outcomes, and no patients showed fair or poor outcomes at the final follow-up evaluation at 1 year. Conclusion: The extraforaminal approach seems to be a safe, less traumatic and less destabilizing approach for managing far lateral lumbar disc herniation and can lead to a better outcome than traditional approaches. (2017ESJ129)
Research Authors
Al Moataz El-Sabrout*, Mohammad El-Sharkawi*, Mohamed
El-Meshtawy*, Romany Zaki
Research Journal
Egyptian Spine Journal
Research Pages
15-22
Research Publisher
Egyptian Spine Association
Research Rank
2
Research Vol
Volume 22, Issue 1
Research Website
https://esj.journals.ekb.eg/article_5633.html
Research Year
2017
Subscribe to