The objective of the present study was to determine the prevalence of poor sleep quality and to assess its psychological and general health correlates among secondary school students in the city of Assiut, Egypt. A cross sectional study was conducted among 829 secondary school students (selected by multistage stratified random sampling) aged 15–19 years in Assiut. Students filled in a self-administered questionnaire that included demographic data, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale, general perception of health, and the short form of Depression Anxiety and Stress Scale. The prevalence of poor sleep quality (PSQI >5) was 72.5%. The mean PSQI score was 7.35 ± 2.94 standard deviation. Poor sleep quality was higher among females, urban residents and public school students. Correlates of poor sleep by multivariate analysis were age, urban residence, public education, mild to moderate and severe to very severe anxiety symptoms, severe to very severe depressive symptoms, excessive daytime sleepiness, and feeling fully active sometimes and not active at any time. Poor sleep quality was alarmingly highly prevalent among secondary school students, with significant health consequences. Increasing the awareness of the community especially adolescents, parents, and school teachers about healthy sleep is an essential priority.

The objective of the present study was to determine the prevalence of poor sleep quality and to assess its psychological and general health correlates among secondary school students in the city of Assiut, Egypt. A cross sectional study was conducted among 829 secondary school students (selected by multistage stratified random sampling) aged 15–19 years in Assiut. Students filled in a self-administered questionnaire that included demographic data, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale, general perception of health, and the short form of Depression Anxiety and Stress Scale. The prevalence of poor sleep quality (PSQI >5) was 72.5%. The mean PSQI score was 7.35 ± 2.94 standard deviation. Poor sleep quality was higher among females, urban residents and public school students. Correlates of poor sleep by multivariate analysis were age, urban residence, public education, mild to moderate and severe to very severe anxiety symptoms, severe to very severe depressive symptoms, excessive daytime sleepiness, and feeling fully active sometimes and not active at any time. Poor sleep quality was alarmingly highly prevalent among secondary school students, with significant health consequences. Increasing the awareness of the community especially adolescents, parents, and school teachers about healthy sleep is an essential priority.

The objective of the present study was to determine the prevalence of poor sleep quality and to assess its psychological and general health correlates among secondary school students in the city of Assiut, Egypt. A cross sectional study was conducted among 829 secondary school students (selected by multistage stratified random sampling) aged 15–19 years in Assiut. Students filled in a self-administered questionnaire that included demographic data, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale, general perception of health, and the short form of Depression Anxiety and Stress Scale. The prevalence of poor sleep quality (PSQI >5) was 72.5%. The mean PSQI score was 7.35 ± 2.94 standard deviation. Poor sleep quality was higher among females, urban residents and public school students. Correlates of poor sleep by multivariate analysis were age, urban residence, public education, mild to moderate and severe to very severe anxiety symptoms, severe to very severe depressive symptoms, excessive daytime sleepiness, and feeling fully active sometimes and not active at any time. Poor sleep quality was alarmingly highly prevalent among secondary school students, with significant health consequences. Increasing the awareness of the community especially adolescents, parents, and school teachers about healthy sleep is an essential priority.

The objective of the present study was to determine the prevalence of poor sleep quality and to assess its psychological and general health correlates among secondary school students in the city of Assiut, Egypt. A cross sectional study was conducted among 829 secondary school students (selected by multistage stratified random sampling) aged 15–19 years in Assiut. Students filled in a self-administered questionnaire that included demographic data, Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale, general perception of health, and the short form of Depression Anxiety and Stress Scale. The prevalence of poor sleep quality (PSQI >5) was 72.5%. The mean PSQI score was 7.35 ± 2.94 standard deviation. Poor sleep quality was higher among females, urban residents and public school students. Correlates of poor sleep by multivariate analysis were age, urban residence, public education, mild to moderate and severe to very severe anxiety symptoms, severe to very severe depressive symptoms, excessive daytime sleepiness, and feeling fully active sometimes and not active at any time. Poor sleep quality was alarmingly highly prevalent among secondary school students, with significant health consequences. Increasing the awareness of the community especially adolescents, parents, and school teachers about healthy sleep is an essential priority.

Computed tomography (CT) cannot differentiate benign from malignant pulmonary lesion.Diffusion weighted magnetic resonance imaging(DW-MRI) can evaluate lung cancer using ADC which is inveresly correlated to tissue cellularity. Objective: To evaluate the role of measurement of ADC in the differentiation between benign and malignant pulmonary lesions. Patients&Methods: 42 patients with pulmonary masses were included in this study. They underwent diffusion weighted MRI. ADC value measurement and histopathological diagnosis were done for each lesion. Results: The mean age for the studied patients was 57.85± 10.6 years with male predominance (34 patients). On histopathological bases they were subdivided into benign (12 patients) and malignant (30patients).The mean ADCx10-3 for the malignant lesions(0.92±0.15) was significantly(p0.001) lower than benign lesions(1.55 ± 0.15) as shown in Figure1 In malignant tumors, ADC value for small cell lung cancer was significantly(p0.05) lower than non small cell lung cancer . Using ADC value of 1.10x10-3 mm2/s as the cut-off threshold for the differentiation between benign and malignant lesions the sensitivity, specificity, PPV and NPP were 96.7% and 83.3%, 93.5% and 90.9% respectively. Conclusion: Diffusion weighted MRI with measurement of ADC value is very helpful in the differentiation between malignant and benign pulmonary lesions

Computed tomography (CT) cannot differentiate benign from malignant pulmonary lesion.Diffusion weighted magnetic resonance imaging(DW-MRI) can evaluate lung cancer using ADC which is inveresly correlated to tissue cellularity. Objective: To evaluate the role of measurement of ADC in the differentiation between benign and malignant pulmonary lesions. Patients&Methods: 42 patients with pulmonary masses were included in this study. They underwent diffusion weighted MRI. ADC value measurement and histopathological diagnosis were done for each lesion. Results: The mean age for the studied patients was 57.85± 10.6 years with male predominance (34 patients). On histopathological bases they were subdivided into benign (12 patients) and malignant (30patients).The mean ADCx10-3 for the malignant lesions(0.92±0.15) was significantly(p0.001) lower than benign lesions(1.55 ± 0.15) as shown in Figure1 In malignant tumors, ADC value for small cell lung cancer was significantly(p0.05) lower than non small cell lung cancer . Using ADC value of 1.10x10-3 mm2/s as the cut-off threshold for the differentiation between benign and malignant lesions the sensitivity, specificity, PPV and NPP were 96.7% and 83.3%, 93.5% and 90.9% respectively. Conclusion: Diffusion weighted MRI with measurement of ADC value is very helpful in the differentiation between malignant and benign pulmonary lesions

Computed tomography (CT) cannot differentiate benign from malignant pulmonary lesion.Diffusion weighted magnetic resonance imaging(DW-MRI) can evaluate lung cancer using ADC which is inveresly correlated to tissue cellularity. Objective: To evaluate the role of measurement of ADC in the differentiation between benign and malignant pulmonary lesions. Patients&Methods: 42 patients with pulmonary masses were included in this study. They underwent diffusion weighted MRI. ADC value measurement and histopathological diagnosis were done for each lesion. Results: The mean age for the studied patients was 57.85± 10.6 years with male predominance (34 patients). On histopathological bases they were subdivided into benign (12 patients) and malignant (30patients).The mean ADCx10-3 for the malignant lesions(0.92±0.15) was significantly(p0.001) lower than benign lesions(1.55 ± 0.15) as shown in Figure1 In malignant tumors, ADC value for small cell lung cancer was significantly(p0.05) lower than non small cell lung cancer . Using ADC value of 1.10x10-3 mm2/s as the cut-off threshold for the differentiation between benign and malignant lesions the sensitivity, specificity, PPV and NPP were 96.7% and 83.3%, 93.5% and 90.9% respectively. Conclusion: Diffusion weighted MRI with measurement of ADC value is very helpful in the differentiation between malignant and benign pulmonary lesions

Computed tomography (CT) cannot differentiate benign from malignant pulmonary lesion.Diffusion weighted magnetic resonance imaging(DW-MRI) can evaluate lung cancer using ADC which is inveresly correlated to tissue cellularity. Objective: To evaluate the role of measurement of ADC in the differentiation between benign and malignant pulmonary lesions. Patients&Methods: 42 patients with pulmonary masses were included in this study. They underwent diffusion weighted MRI. ADC value measurement and histopathological diagnosis were done for each lesion. Results: The mean age for the studied patients was 57.85± 10.6 years with male predominance (34 patients). On histopathological bases they were subdivided into benign (12 patients) and malignant (30patients).The mean ADCx10-3 for the malignant lesions(0.92±0.15) was significantly(p0.001) lower than benign lesions(1.55 ± 0.15) as shown in Figure1 In malignant tumors, ADC value for small cell lung cancer was significantly(p0.05) lower than non small cell lung cancer . Using ADC value of 1.10x10-3 mm2/s as the cut-off threshold for the differentiation between benign and malignant lesions the sensitivity, specificity, PPV and NPP were 96.7% and 83.3%, 93.5% and 90.9% respectively. Conclusion: Diffusion weighted MRI with measurement of ADC value is very helpful in the differentiation between malignant and benign pulmonary lesions

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An isolated fraction with bradykinin potentiating activity, from the venom of the Egyptian scorpion Buthus occitanus, was injected i.p. in female mice (35 days old). Five days after the injection of a single sublethal dose (1 μg/g), the number of primary multilaminar and secondary follicles of the ovaries was increased. Graafian follicles were observed in 50% of the treated mice but in none of the control mice. The number and size of the uterine glands and endometrium were increased in treated mice. Concomitantly, estradiol was increased in the circulating blood, while progesterone was within the normal limits. The enhancement of cellular growth by the isolated venom fraction with bradykinin potentiating activity, could be attributed to an enhancement of some growth factor(s) responsible for stimulating the ovarian follicles and uterus.