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Squamous Cell Carcinoma of the Cornea and Conjunctiva Treated by Surgical Excision and a Combination of MMC and 5-FU Eye Drops: Case Report

Research Abstract
Squamous cell carcinoma of the conjunctiva (SCC) is considered as one of the ocular surface squamous neoplasia (OSSN). It is the most common conjunctival malignancy. In this report, we describe the short term success of surgical excision, followed by topical chemotherapy, with 5-fluorouracil (5-FU) and mitomycin C (MMC) eye drops, in a 43-year old Egyptian woman.
Research Authors
Ashraf K. Al-Hussaini, Sana S. Kroosh, Khaled Abdelazeem, Enass Elia, Raafat Fekry Michael
Research Department
Research Journal
EC Ophthalmology
Research Pages
247-252
Research Publisher
E-Cronicon
Research Rank
1
Research Vol
10-4
Research Website
https://www.ecronicon.com/ecop/volume10-issue4.php
Research Year
2019

Squamous Cell Carcinoma of the Cornea and Conjunctiva Treated by Surgical Excision and a Combination of MMC and 5-FU Eye Drops: Case Report

Research Abstract
Squamous cell carcinoma of the conjunctiva (SCC) is considered as one of the ocular surface squamous neoplasia (OSSN). It is the most common conjunctival malignancy. In this report, we describe the short term success of surgical excision, followed by topical chemotherapy, with 5-fluorouracil (5-FU) and mitomycin C (MMC) eye drops, in a 43-year old Egyptian woman.
Research Authors
Ashraf K. Al-Hussaini, Sana S. Kroosh, Khaled Abdelazeem, Enass Elia, Raafat Fekry Michael
Research Department
Research Journal
EC Ophthalmology
Research Pages
247-252
Research Publisher
E-Cronicon
Research Rank
1
Research Vol
10-4
Research Website
https://www.ecronicon.com/ecop/volume10-issue4.php
Research Year
2019

Causes and Clinical Impact of Loss to Follow-Up in Patients with Proliferative Diabetic Retinopathy

Research Abstract
Purpose: This study determined the clinical impact and causes of loss to follow-up (LTFU) from the patients’ perspective in individuals with proliferative diabetic retinopathy (PDR) who received panretinal photocoagulation (PRP) and/or intravitreal injections (IVIs) of anti-vascular endothelial growth factor (VEGF). Methods: This prospective cohort study included 467 patients with PDR who received PRP and/or IVIs of anti-VEGF between May 2013 and June 2018. LTFU was defined as missing any follow-up visit for any interval exceeding 6 months, provided that patients eventually resumed care. Main outcome measures include rates and causes of LTFU. Results: A total of 391 patients (83.7%) were followed, and 76 patients (16.3%) were LTFU over the study period. Rates of LTFU decreased with age (P = 0.005). Questionnaire analysis conducted for patients LTFU showed a significant positive correlation between best corrected visual activity (BCVA) loss and patient’s lack of trust and satisfaction with treatment [rs = 0.458, P 0.001]. There was also a significant positive correlation between treatment unaffordability and number of IVIs of anti-VEGF [rs = 0.55, P 0.001] and lack of social support and age [rs = 0.39, P 0.001]. Conclusions: LTFU threatens vision in PDR patients receiving PRP and/or IVIs of anti-VEGF. Possibly, patient-specific LTFU causes should be addressed before treatment in order to minimize the risk of LTFU.
Research Authors
Hazem Abdelmotaal, Walid Ibrahim, Mohamed Sharaf, Khaled Abdelazeem
Research Department
Research Journal
Journal of Ophthalmology
Research Member
Research Pages
8
Research Publisher
Hindawi
Research Rank
1
Research Vol
NULL
Research Website
https://www.hindawi.com/journals/joph/2020/7691724/
Research Year
2020

Causes and Clinical Impact of Loss to Follow-Up in Patients with Proliferative Diabetic Retinopathy

Research Abstract
Purpose: This study determined the clinical impact and causes of loss to follow-up (LTFU) from the patients’ perspective in individuals with proliferative diabetic retinopathy (PDR) who received panretinal photocoagulation (PRP) and/or intravitreal injections (IVIs) of anti-vascular endothelial growth factor (VEGF). Methods: This prospective cohort study included 467 patients with PDR who received PRP and/or IVIs of anti-VEGF between May 2013 and June 2018. LTFU was defined as missing any follow-up visit for any interval exceeding 6 months, provided that patients eventually resumed care. Main outcome measures include rates and causes of LTFU. Results: A total of 391 patients (83.7%) were followed, and 76 patients (16.3%) were LTFU over the study period. Rates of LTFU decreased with age (P = 0.005). Questionnaire analysis conducted for patients LTFU showed a significant positive correlation between best corrected visual activity (BCVA) loss and patient’s lack of trust and satisfaction with treatment [rs = 0.458, P 0.001]. There was also a significant positive correlation between treatment unaffordability and number of IVIs of anti-VEGF [rs = 0.55, P 0.001] and lack of social support and age [rs = 0.39, P 0.001]. Conclusions: LTFU threatens vision in PDR patients receiving PRP and/or IVIs of anti-VEGF. Possibly, patient-specific LTFU causes should be addressed before treatment in order to minimize the risk of LTFU.
Research Authors
Hazem Abdelmotaal, Walid Ibrahim, Mohamed Sharaf, Khaled Abdelazeem
Research Department
Research Journal
Journal of Ophthalmology
Research Member
Research Pages
8
Research Publisher
Hindawi
Research Rank
1
Research Vol
NULL
Research Website
https://www.hindawi.com/journals/joph/2020/7691724/
Research Year
2020

Causes and Clinical Impact of Loss to Follow-Up in Patients with Proliferative Diabetic Retinopathy

Research Abstract
Purpose: This study determined the clinical impact and causes of loss to follow-up (LTFU) from the patients’ perspective in individuals with proliferative diabetic retinopathy (PDR) who received panretinal photocoagulation (PRP) and/or intravitreal injections (IVIs) of anti-vascular endothelial growth factor (VEGF). Methods: This prospective cohort study included 467 patients with PDR who received PRP and/or IVIs of anti-VEGF between May 2013 and June 2018. LTFU was defined as missing any follow-up visit for any interval exceeding 6 months, provided that patients eventually resumed care. Main outcome measures include rates and causes of LTFU. Results: A total of 391 patients (83.7%) were followed, and 76 patients (16.3%) were LTFU over the study period. Rates of LTFU decreased with age (P = 0.005). Questionnaire analysis conducted for patients LTFU showed a significant positive correlation between best corrected visual activity (BCVA) loss and patient’s lack of trust and satisfaction with treatment [rs = 0.458, P 0.001]. There was also a significant positive correlation between treatment unaffordability and number of IVIs of anti-VEGF [rs = 0.55, P 0.001] and lack of social support and age [rs = 0.39, P 0.001]. Conclusions: LTFU threatens vision in PDR patients receiving PRP and/or IVIs of anti-VEGF. Possibly, patient-specific LTFU causes should be addressed before treatment in order to minimize the risk of LTFU.
Research Authors
Hazem Abdelmotaal, Walid Ibrahim, Mohamed Sharaf, Khaled Abdelazeem
Research Department
Research Journal
Journal of Ophthalmology
Research Pages
8
Research Publisher
Hindawi
Research Rank
1
Research Vol
NULL
Research Website
https://www.hindawi.com/journals/joph/2020/7691724/
Research Year
2020

Causes and Clinical Impact of Loss to Follow-Up in Patients with Proliferative Diabetic Retinopathy

Research Abstract
Purpose: This study determined the clinical impact and causes of loss to follow-up (LTFU) from the patients’ perspective in individuals with proliferative diabetic retinopathy (PDR) who received panretinal photocoagulation (PRP) and/or intravitreal injections (IVIs) of anti-vascular endothelial growth factor (VEGF). Methods: This prospective cohort study included 467 patients with PDR who received PRP and/or IVIs of anti-VEGF between May 2013 and June 2018. LTFU was defined as missing any follow-up visit for any interval exceeding 6 months, provided that patients eventually resumed care. Main outcome measures include rates and causes of LTFU. Results: A total of 391 patients (83.7%) were followed, and 76 patients (16.3%) were LTFU over the study period. Rates of LTFU decreased with age (P = 0.005). Questionnaire analysis conducted for patients LTFU showed a significant positive correlation between best corrected visual activity (BCVA) loss and patient’s lack of trust and satisfaction with treatment [rs = 0.458, P 0.001]. There was also a significant positive correlation between treatment unaffordability and number of IVIs of anti-VEGF [rs = 0.55, P 0.001] and lack of social support and age [rs = 0.39, P 0.001]. Conclusions: LTFU threatens vision in PDR patients receiving PRP and/or IVIs of anti-VEGF. Possibly, patient-specific LTFU causes should be addressed before treatment in order to minimize the risk of LTFU.
Research Authors
Hazem Abdelmotaal, Walid Ibrahim, Mohamed Sharaf, Khaled Abdelazeem
Research Department
Research Journal
Journal of Ophthalmology
Research Pages
8
Research Publisher
Hindawi
Research Rank
1
Research Vol
NULL
Research Website
https://www.hindawi.com/journals/joph/2020/7691724/
Research Year
2020

Urethral Stone in a Young Girl: A Transit in a Normal Urethra

Research Abstract
Urethral stones in females are very rare and always associated with genitourinary pathology. We report on a 9-year-old girl with a history of a small left ureteral stone that was diagnosed by abdominal radiograph and ultrasonography and subjected for conserva-tive management. On a follow up visit, she complained of dysuria for a few hours, while the passage of the stone was denied. Exami-nation of the urethral meatus revealed nothing. Follow up abdominal ultrasonography revealed resolution of renal obstruction with free both kidneys and urinary bladder. However, abdominal plain radiograph showed migration of the stone from the course of the left lower ureter into the course of the urethra. The patient was asked to void, where a small stone passed spontaneously. The note here is the transient lodgment of the stone in the normal urethra without urinary retention which represents an unusual scenario of urethral stones in young girls.
Research Authors
Rabea Ahmed Gadelkareem; Mohammed Abdallah Elgammal
Research Department
Research Journal
EC Paediatrics
Research Pages
99-102
Research Publisher
ECronicon
Research Rank
1
Research Vol
Vol. 8, No. 2
Research Website
NULL
Research Year
2019

Urethral Stone in a Young Girl: A Transit in a Normal Urethra

Research Abstract
Urethral stones in females are very rare and always associated with genitourinary pathology. We report on a 9-year-old girl with a history of a small left ureteral stone that was diagnosed by abdominal radiograph and ultrasonography and subjected for conserva-tive management. On a follow up visit, she complained of dysuria for a few hours, while the passage of the stone was denied. Exami-nation of the urethral meatus revealed nothing. Follow up abdominal ultrasonography revealed resolution of renal obstruction with free both kidneys and urinary bladder. However, abdominal plain radiograph showed migration of the stone from the course of the left lower ureter into the course of the urethra. The patient was asked to void, where a small stone passed spontaneously. The note here is the transient lodgment of the stone in the normal urethra without urinary retention which represents an unusual scenario of urethral stones in young girls.
Research Authors
Rabea Ahmed Gadelkareem; Mohammed Abdallah Elgammal
Research Department
Research Journal
EC Paediatrics
Research Pages
99-102
Research Publisher
ECronicon
Research Rank
1
Research Vol
Vol. 8, No. 2
Research Website
NULL
Research Year
2019

Experience of a Tertiary-Level Urology Center in the Clinical Urological Events of Rare and Very Rare Incidence. I. Surgical Never Events: 3. Urological Electrosurgical Never Events

Research Abstract
Introduction:Surgical fires are unique topics that belong to surgical never events and deserve urological attention. Materials and Methods:A retrospective search of our hospital records was done for the states of electrosurgical never events in the period from July 2001 to June 2016. The included events were classified according to the site of occurrence in relation to the patient's body and possibilities of human involvement. The events were studied for the type, extent, damages, personnel involvements, complications, and management. Results:Of more than 82,000 urological interventions, 18 cases (0.022%) of electrosurgical never events were detected. Four subcategories were differentiated: electrosurgical theater fires (33.3%), electrosurgical contact skin burns (38.9%), electrosurgical internal injuries (16.7%), and electrocutions (11.1%). Electrosurgical theater fires included 3 ignition fires with fire skin burns and 3 device explosions. Fires only occurred with the use of alcoholic skin disinfectants. Contact skin burns resulted from inadvertent direct electrosurgical contacts, with 2 burns on the back, 3 burns on the lower limbs, 1 burn at the penile shaft, and 1 burn at the suprapubic region. Only 1 case of contact skin burn required plastic surgery. Electrosurgical internal in-juries involved the intestine, spleen, and urethra and were followed by major complications. Electrocutions involved a doctor and a patient with multiple bone fractures in the former. Conclusion:Urological electrosurgical never events are very rare incidents and were differentiated into 4 clinical subcategories. Human involvements varied from absence to major devastating complications. Reduction of these events depends on the adjusted use of electricity-based armamentarium.
Research Authors
Rabea A. Gadelkareem
Research Department
Research Journal
Current Urology
Research Pages
33-38
Research Publisher
KARGER AG, Basel
Research Rank
1
Research Vol
Vol. 12, No. 1
Research Website
10.1159/000447228
Research Year
2018

Abdominoscrotal hydrocele: A systematic review and proposed clinical grading

Research Abstract
Introduction: Abdominoscrotal hydrocele is a rare hydrocele variant in pediatrics and adults. Besides the historical concerns, controversies in etiology and management of abdominoscrotal hydrocele warrant studying. Subjects and methods: A systematic review was conducted based on a multilingual search of the world liter- ature of abdominoscrotal hydrocele through electronic engines (Google Scholar and MEDLINE/PubMed). The demographic and clinical characteristics are critically addressed and a clinical grading system is proposed. Results: From the 487 delivered articles, 320 articles were eligible to this review including only 21 case series. They delivered 579 abdominoscrotal hydrocele cases. Abdominoscrotal hydrocele affects pediatrics more than adults with significantly increased rate of reporting in the last decades. Full or incomplete case descriptions were found in 558 cases versus 21 cases with deficient description. Abdominoscrotal hydrocele has been reported from 45 countries and India has the highest rate. Eight proposed hypotheses were differentiated for etiology and grouped according to the direction of fluid formation and hydrocele growth. Associated congenital anomalies include contralateral hydroceles and cryptorchidism. Complications result from compression, hemorrhage, infection, torsion, and coincident malignancy. A clinical grading system considering the increased anatomical, pathological or clinical complexities has been proposed and provided two categories; simple and complex abdominoscrotal hydroceles with further sub-classes. Conclusions: Abdominoscrotal hydrocele is rare, but the number of the reported cases is far larger than the previously reported numbers. Etiology follows multiple hypotheses and management is speculative. Proposed clinical grading may support differentiation of severity of the associated cumulative risks.
Research Authors
Rabea Ahmed Gadelkareem
Research Department
Research Journal
African Journal of Urology
Research Pages
83-92
Research Publisher
Elsevier
Research Rank
1
Research Vol
Vol. 24, No. 2
Research Website
https://doi.org/10.1016/j.afju.2018.01.006
Research Year
2018
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