Hardware implementation of neural networks (NNs) is challenging due to varying application requirements. This often necessitates creating specific field programmable gate arrays (FPGAs) configurations from scratch for each application. This article proposes a flexible, self-supervised reconfigurable method to fit several application requirements by providing only the maximum available computational nodes a priori. The proposed method dynamically reconfigures the required number of hidden layers and nodes based on the application. The goal is to automatically determine the optimal NN configuration through reconfigurability to achieve maximum accuracy. Optimality is demonstrated through minimum average power, average delay, and area overhead, as well as maximum throughput and accuracy. Experimental results show that the proposed approach significantly reduces the optimized architecture search …