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Effect of prostaglandin B1,F1α and F2 α on thyroxine, triiodothyronine and calacium level in albino rat serum

Research Abstract
Released T4 and T3 hormones in albino rat blood after an exogenous administration of PGB1, PG1α and PGF2α were determined and correlated with the serum content of calcium. Results revealed that all the tested PGs significantly raised the levels of T3 and T4 in rat serum, but not affect the serum calcium levels. PGB1 and PGF1α reduced the thyroidal calcium content due to enhancing the ellular permeability. However, the effect of PGF2α due to enhancing the lysosomal proteolytic enzyme activity.
Research Authors
A.Y.Nasser
K.A.Hassan
Hossam El-Din M Omar
Research Journal
Assiut J. of Agricultural Sciences
Research Pages
43-56
Research Publisher
Faculty of Agricultural, Assiut Univ.
Research Rank
2
Research Vol
19:2
Research Year
1988

Histophysiological studies on the efficiency of antioxidants: alpha-lipoic acid and N-acetylcysteine in the kidney of diabetic rabbits

Research Abstract
Oxidative stress induced hyperglycemia plays a central role in the pathogenesis of diabetes and its complications in most of the tissues. In the present study the protective roles of lipoic acid and n-acetylcysteine for the treatment of oxidative stress in alloxan-induced diabetic rabbits were studied. The obtained results concluded that lipoic acid or N-acetylcystiene my be hseful for the therapy of oxidative stress associated with hyperglycemia. The beneficial action seems to result mainly from direct scavenging of ROS and restoring glutathione redox state.
Research Authors
Hossam El-Din M Omar
Abdel-Tawab HS
Al-Salahy MB
Saad El-Dien HM
Saeed MA
Research Journal
Assiut J of Zoology
Research Pages
181-209
Research Publisher
Faculty of Science, Assiut Univ.
Research Rank
3
Research Vol
Special Publ. N0 2
Research Year
2009

Role of tannic acid as antioxidant in reduction of the oxiative damage of aluminium chloride in the rat's brain

Research Abstract
The experiment was designed to investigate the role of tannic acid as antioxidant in reduction of the oxidtive damage of ALCL3 in the brin of rat The obtained biochemical and histological results documentd that tannic acid has a prophylactic role in reducing the oxidaive amage in the bain tissues that caused by ALCL3 exposure for80 days in drinking water.
Research Authors
K.A.Hassan
Hossam El-Din M.Omar
S.Kh.Abdel-Elghafar
E.AA.Abdel-Gabber
Research Journal
Assiut Vet.Med.J
Research Pages
100-115
Research Publisher
Vet.Med.Faculty
Research Rank
2
Research Vol
48:95
Research Year
2002

Aluminum toxicity in rats: the role of tannic acid as antioxidant

Research Abstract
Pospectiv studies suggest that tea may protect against oxidative stress that induced tissue damage. A potential mechanism fr such effect y polyphenolc antioxidant tannic acid derived from tea was evaluated in tis study. Treatment of rats with ALCL3 for 80 days caused moderate toxicity on liver, kidney and splen as evidenced by increased LPO& No and a reduction of SOD,CAT, GST, GSH nd vitamin E.As well as histopathological changes.However improvement was noticed in the rats treated with tannic acid.
Research Authors
Hossam El-Din M.Omar
Khadiga A.Hassan
Abdel-Elghaffar S.Kh
Ahmed E.A
Research Journal
Assiut Univ.Environ.Res.
Research Pages
1-14
Research Publisher
Assiut University
Research Rank
2
Research Vol
6:2
Research Year
2003

Coexistence of high levels of cortisol and oxidative stress as an indicator in retained placenta in buffalo-cows

Research Abstract
During the late pregnancy and during parturition in bovine, sevearl hormones and reoxygenation of placental tissues and consequences oxidative stress were involved. In this study blood samples from pregnant cows in the last three weeks of pregnancy were taken. At parturition 10 animals were selected as normal parturition and non-retaind placental expulsion. Other 10 cows were selected with normal parturition and retaind placenta. Another blood samples were taken after 1, 24 and 48 hours postpartum from both the obivois groups. The study concluded that oxidative stress and cortisol hormone might play an important role in the process of parturition in cows. It was also found that the extra-elevation of the LPO, NO and cortisol and the reduction of antioxidants could be used as indictor for the possibility of retention of fetal membrane after parturition.
Research Authors
Gaber A.Magahed
Mamadouh M. Anwar
Hossam El-Din M Omar
Research Journal
Zag.Vet.J.
Research Pages
131-140
Research Publisher
Zag.Vet.Med.
Research Rank
2
Research Vol
31 (1)
Research Year
2003

Coexistence of high levels of cortisol and oxidative stress as an indicator in retained placenta in buffalo-cows

Research Abstract
During the late pregnancy and during parturition in bovine, sevearl hormones and reoxygenation of placental tissues and consequences oxidative stress were involved. In this study blood samples from pregnant cows in the last three weeks of pregnancy were taken. At parturition 10 animals were selected as normal parturition and non-retaind placental expulsion. Other 10 cows were selected with normal parturition and retaind placenta. Another blood samples were taken after 1, 24 and 48 hours postpartum from both the obivois groups. The study concluded that oxidative stress and cortisol hormone might play an important role in the process of parturition in cows. It was also found that the extra-elevation of the LPO, NO and cortisol and the reduction of antioxidants could be used as indictor for the possibility of retention of fetal membrane after parturition.
Research Authors
Gaber A.Magahed
Mamadouh M. Anwar
Hossam El-Din M Omar
Research Journal
Zag.Vet.J.
Research Pages
131-140
Research Publisher
Zag.Vet.Med.
Research Rank
2
Research Vol
31 (1)
Research Year
2003

Some antioxidants activities, lipid peroxide and nitric oxide levels in follicular fluid and its relation to oocyte quality in buffalo-cows

Research Abstract
The present study found that antioxidant and the changes in LPO and NO levels were subjected to marked changes in the course of follicular growth during luteal phase of estrous cycle in buffalo-cows. These changes in the intra-folicular environment may reflect the follicular requirements for growth, maturation and maintenance of viability of oocyte in buffalo-cows.
Research Authors
A.El-Din Zain
Hossam El-Din M Omar
Research Journal
Assiut Vet.Med.J.
Research Pages
293-309
Research Publisher
Faculty of Vet. Med. assiut Univ
Research Rank
2
Research Vol
49 (96)
Research Year
2003

Efficacy of 2,3-dimercaptopropanol (BAL) and 2,3-dimercapto-ipropane sulfate (DMPS) on long-term mercuric chloride exposure in rats: Toxicological and pathological studies.

Research Abstract
The study found that the use of BAL and DMPS as chelating agents after long-term of mercuric exposure resulted in considerable recovery in the histopathological, hematological. and biochemical alteration that induced by mercury. However, DMPS has a relative better effect due to its water solubility, less toxicity and its ability to chelate with more metal ions.
Research Authors
Sharkawy A.A.
Abdel-Elghaffar S.Kh
Hossam El-Din M Omar
Research Journal
proceedings of the 15 th Annual Conference for the Egyptian Society of Toxicology" Environmental pollutants and drug ineratction"
Research Pages
19-41
Research Publisher
Egyptian Society of Toxicology
Research Rank
4
Research Vol
Proceedings
Research Year
1999

Efficacy of 2,3-dimercaptopropanol (BAL) and 2,3-dimercapto-ipropane sulfate (DMPS) on long-term mercuric chloride exposure in rats: Toxicological and pathological studies.

Research Abstract
The study found that the use of BAL and DMPS as chelating agents after long-term of mercuric exposure resulted in considerable recovery in the histopathological, hematological. and biochemical alteration that induced by mercury. However, DMPS has a relative better effect due to its water solubility, less toxicity and its ability to chelate with more metal ions.
Research Authors
Sharkawy A.A.
Abdel-Elghaffar S.Kh
Hossam El-Din M Omar
Research Journal
proceedings of the 15 th Annual Conference for the Egyptian Society of Toxicology" Environmental pollutants and drug ineratction"
Research Pages
19-41
Research Publisher
Egyptian Society of Toxicology
Research Rank
4
Research Vol
Proceedings
Research Year
1999

Possible role of oxidants/antioxidant imblance on postpartum ovarian resumption in dairy cows

Research Abstract
The objective of this study was to determine the relationship of postpartum oxidative stress and the ovarian anoestrus in the dairy cows. The study concluded that excess free radical production with elevation of the cortisol hormone might play a role in the prolongation of the postpartum anoestrus in dairy cows. These may be due to exhaustion of antioxidant system in milk production, so it was advise supplementation the dam with antioxidants during the late stage of pregnancy and in postpartum period to stimulate the normal ovarian activity and cyclicity.
Research Authors
Megahed G.A.
Anwar M.M.
Hossam El-Din M. Omar
Research Journal
Egypt.J. Basic Appl. Physiol.
Research Pages
243-261
Research Publisher
Society of physiological Sciences and their applications
Research Rank
2
Research Vol
2
Research Year
2003
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