Abstract

Aim: The objective of this study is to investigate the effect of fennel extract on tongue squamous cell carcinoma cell line and to assess the expression of the Bcl-2 gene in tongue squamous cell carcinoma cells treated with fennel extract.

Materials and Methods: The HNO-97 cell line of tongue squamous cell carcinoma was acquired from the Cell Culture Department NAWAH-Scientific in Cairo, Egypt. Fennel seed extraction was performed at NAWAHScientific in Cairo, Egypt. Cells' cytotoxicity was measured using the MTT assay. The expression of the Bcl-2 gene was assessed by western blotting technique. Cell death mode was identified through microscopic examination as well as image morphometric analysis. The outcomes underwent statistical testing through analysis of variance (ANOVA) test and Post Hoc test (Bonferroni).

Results: The MTT test indicated that the HNO-97 cells displayed sensitivity to fennel extract, showing an IC₅₀ of 2.80 mg/ml. Bcl-2 gene expression first decreased and then increased at post-IC₅₀ concentration, as determined by western blotting. The mean values of NAF decreased initially and then increased at post-IC₅₀ concentration, according to image morphometric analysis. The P-value was less than 0.05 so, the results were considered significant.

Conclusion: IC₅₀ concentration of fennel extract has the best cytotoxic effect on the HNO-97 cell line of tongue squamous cell carcinoma.

This study aimed to evaluate the clinical and radiographic outcomes of premixed bioceramic putty as a direct pulp capping in primary molars over a 12-month follow-up period.

Methods

This study included forty primary molars with deep occlusal carious lesions, whose removal resulted in pulp exposure. They were treated with direct pulp capping using premixed bioceramic putty. All teeth were covered using high viscosity glass ionomer and immediately restored with stainless steel crowns to ensure proper seal. Clinical examinations were conducted at 3, 6, 9, and 12 months, while radiographic examinations were conducted at 6 and 12 months follow up interval.

Results

Forty teeth were available for follow up. By the end of the 12 months, the overall clinical and radiographic success was 87.5%.

Conclusions

Radiographic and clinical outcomes of premixed bioceramic putty could suggest it as an effective …

Statement of problem

Intraoral scanning of complete arch implant-supported prosthesis is still not predictable in all scenarios. Photogrammetry was introduced to overcome physical and anatomic limitations. The use of a new intraoral scanner combined with photogrammetry technology in a simplified workflow may improve the ease of fabrication and accuracy of complete arch implant-supported prostheses.

Purpose

The purpose of this clinical study was to evaluate the degree of trueness of a conventional intraoral scanner (IOS) and an intraoral photogrammetry scanner (IPS) for complete arch implant-supported prostheses.

Material and methods

Participants who had received 4 implants in an edentulous arch for an implant-supported complete arch fixed dental prosthesis were recruited. Three recordings were obtained for each participant: IOS, IPS (tests), and a conventional splinted open-tray impression (reference …

This study aimed to evaluate the clinical performance (degree of trueness) of a novel scan body “tooth-modified Scan body” (TMSB)& conventional scan body (CSB) in implant-supported full arch screw retained cases.

Methods

Seven edentulous arches (two maxillae, five mandibles) in 6 patients were rehabilitated with monolithic zirconia screw-retained implant prostheses supported by 4 (n = 1) and 5 implants (n = 6) for a total amount of 34 implants. Implant locations were scanned by intra-oral scanner (IOS) using two types of scan bodies, conventional scan bodies (CSB) in group (1) and tooth-modified scan bodies (TMSB) in group (2). 68 implant positions (representing the total sample size) were captured and compared to the relative reference scans regarding angular and Euclidian deviation (ΔEUC).

Results

The ΔEUC deviation Of TMSB group had lower values (M = 61.46, SD = 42.12) than that …