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Third Scientific Day for the Nursing Staff and Healthcare Providers

The third scientific and awareness day organized by the Community Service and Environmental Development Sector for the nursing staff and healthcare providers at the University Dental Hospital on Sunday, January 5, 2025.

Dr. Muhammad Esam Aref delivered a lecture entitled "Orthodontic Problems in Children".

 

 

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Surveys for Faculty Members

The Faculty of Dentistry is asking its staff to complete the following surveys.

الاحتياجات التدريبية : https://forms.gle/7K2R1abU3LZBpkki6

استبيان الرضا الوظيفي : https://forms.gle/AdCcdcz7aXVkeVcU7

استبيان لقياس مردود الدورات التدريبية : https://forms.gle/CTdJiHB9torPwyJf6

نموذج تقويم الاداء الوظيفي للقيادات الأكاديمية : https://forms.gle/MeU5KkUM4LSybxx2A

 

Third Scientific Day for the Nursing Staff and Healthcare Providers

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Dr. Muhammad Esam Aref will deliver a lecture entitled "Orthodontic Problems in Children" at the Faculty of Dentistry's Third Scientific Day for Nursing Staff and Healthcare Providers. The event, will be organized by the Community Service and Environmental Development Sector, on Sunday, January 5, 2025, at 8:00 a.m. in the Postgraduate Studies Hall.

Urgent Warning: Fraudulent Activities Targeting Students Enrolled in Military Education Courses

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It has recently come to our attention that some students have reported instances of fraud perpetrated by individuals and groups on social media platforms. These scams involve requests for financial payments or transfers via Vodafone Cash in exchange for purported completion of the Military Education course.

Therefore, all students are hereby instructed to conduct all matters related to Military Education courses exclusively with the Military Education Administration within the university. The Military Education Administration bears no responsibility for any fraudulent activities encountered by students, whether through social media or via telephone.

Furthermore, it has been brought to the attention of the university's Military Education officials that an individual named "Islam," using mobile number 01028448805, has been contacting students.

When registering for Military Education courses, students are required to personally visit the administration with their valid National ID card and Faculty ID card for registration purposes.

"Geniuses of the Faculties" Competition

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The Cultural Activities Administartion of the General Administration of Student Welfare hereby announces the organization of the "Geniuses of the Faculties" league, a competition open to all students of Assiut University. The competition will be held from December 2nd, 2024, to February 27th, 2025.

Students possessing demonstrable skill in general knowledge and the aptitude to represent the Faculty of Dentistry in the "Geniuses of the Faculties" league are invited to register their participation. Interested students should proceed to the Faculty's Student Welfare Administration to register their names. The registration deadline is Thursday, January 9th, 2025.

Trip To Aswan

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The Student Welfare Administration organizes a two-day trip to Aswan on January 10th and 11th, 2025. The trip is organized in collaboration with the Student Union. The cost is 900 LE, which covers transportation, meals, and lodging. Interested students should contact the Student Welfare Administration.

ROLE OF ESTROGEN ON THE ORAL TISSUE INTEGRITY

Research Abstract

The oral cavity is comprised of several structures that have different functions and reflect the overall health. Sex hormones are steroids produced from cholesterol. They are secreted in the mouth with saliva that is thought to possess some healing properties. Many studies have been aimed at the impacts of hormone fluctuations on certain types of oral tissues, especially periodontal tissues. There are numerous changes experienced as a result of hypoestrogenism among them being oral alterations. Local changes include a reduction of salivary function leading to decreased salivation and a predisposition of the oral mucosa to ulceration. Also in the oral cavity, xerostomia may make tooth caries more frequent. Added to the reduction of saliva, the gingival epithelium also becomes less robust, thus may further result in increased tooth mobility and possibly tooth loss due to the risk of invasion by bacteria and reduced alveolar bone mineral density for bone resorption. Since periodontal disease is one of the things that lowers quality of life, prevention and treatment of this damage are needed. To locate studies that address it, the main question to search for is: “Has there been any relationship between the concentration of estrogen in the body fluids and the integrities and healthy status of the oral tissues?". This review revealed that the balance of the body's estrogen hormone with the periodontium is fixed. The objective of the present search was to establish whether intact and healthy oral tissues are linked with sex hormones within body fluids. So the dentist has a good understanding of hormonal changes in women, and how they affect gingival diseases.

Research Authors
ATEF I. AHMED, FIRAS D. ALSOLEIHAT, MAHMOUD A. ATTIA, AHMED M. HUSSEIN
Research Date
Research Department
Research Journal
Assiut Veterinary Medical Journal
Research Pages
684-698
Research Publisher
Assiut University, Faculty of Veterinary Medicine
Research Vol
71
Research Website
10.21608/AVMJ.2025.328197.1435
Research Year
2025

Expression of Matrix Metalloproteinase-9, P53 and B-cl2 Genes in Human Osteosarcoma Cell Line Treated with Ginger Extract

Research Abstract

Abstract

Aim: The current study was designed to explore the potential effect of ginger extract on the osteosarcoma cell line (MG-
63).
 

Material and Methods: Human osteosarcoma cell line (MG-63) was acquired from Nawah-Scientific. The tested drug was
ginger extract prepared by maceration in semi-liquid form. The potential impact of ginger extract upon MG-63 cells was
evaluated using cytotoxicity assay, microscopic evaluation, Enzyme-Linked Immunosorbent Assay for evaluation of Matrix
Metalloproteinase-9 (MMP-9), and Real-Time Polymerase Chain Reaction for detection of the expression levels of the proapoptotic
gene (P53) and antiapoptotic gene B-cell lymphoma 2 (B-cl2) in ginger extract-treated cells. Then the data
collected was statistically assessed.
 

Results: The outcomes demonstrated that ginger extract's cytotoxic impact upon MG-63 cells was dose-dependent, as
viability increased as long as the concentration decreased. Under the microscope, MG-63 cells treated with ginger extract
displayed apoptotic signs such as chromatin condensation, cell shrinkage, and plasma membrane blebbing. Data about
MMP-9 showed that, ginger extract dramatically and dose-dependently reduced MMP-9 levels. Regarding P53 and B-cl2,
data revealed that ginger extract significantly increased P53 levels and decreased B-cl2 in a dose-dependent manner.
 

Conclusion: Ginger extract substantially diminishes the viability of osteosarcoma cells because of its strong cytotoxic
activity against MG-63 cells.

Research Authors
Hend Mohamed Ali Hashem1, Enas Alaa Eldin Abd El-Aziz2, Aly Fahmy Mohamed3, Sabreen Gamal Khalil Amar4
Research Date
Research Department
Research Journal
Ain Shams Dental Journal
Research Member
Research Pages
232-243
Research Publisher
Ain Shams Dental Journal
Research Rank
Local
Research Vol
35
Research Website
https://asdj.journals.ekb.eg/article_383035.html
Research Year
2024

Bone marrow derived mesenchymal stem cells restored GLUT1 expression in the submandibular salivary glands of ovariectomized rats

Research Abstract

Abstract

Objective: Loss of ovarian function in menopause is commonly associated with salivary gland dysfunction. The aim is to study the possible therapeutic effect of bone marrow mesenchymal stem cells (BM-MSCs) on the altered structure of the submandibular salivary glands (SMGs) of ovariectomized rats.

Design: Twenty-four female, adult, Wistar rats were used and distributed into three groups (8 rats/group). The control group included sham-operated rats. The ovariectomized group consisted of rats with removed ovaries. The third group consisted of ovariectomized rats received injections, via tail, of MSCs extracted from bone marrow of 3-weeks-old rat hind limb (BM-MSC group). Four weeks after BM-MSC transplantation, the bone mineral density (BMD) of the femur was detected. The SMG was dissected and processed for histological, immunohistochemical, and histomorphometric analyses.

Results: The ovariectomized rats depicted low BMD in the femur. The SMG acini revealed atrophy. The ductal and acinar cells depicted vacuolization and abnormal nuclear histology. GLUT1 immunostaining was decreased in SMG ducts. The BM-MSC group resumed the normal SMG histology and GLUT1 immunolabelling.

Conclusions: BM-MSC therapy restored the normal SMG structure and GLUT1 immunostaining in the treated ovariectomized rats, suggesting improved glucose transporting function.

Research Authors
Menna Abdulqader El-Badawy 1, Mohamed Badawy 2, Maha El Shahawy 3
Research Date
Research Department
Research Journal
Arch Oral Biol
Research Pages
106048
Research Publisher
Arch Oral Biol
Research Rank
International
Research Vol
166
Research Website
https://pubmed.ncbi.nlm.nih.gov/39002180/#:~:text=Conclusions%3A%20BM-MSC%20therapy%20restored,suggesting%20improved%20glucose%20transporting%20function
Research Year
2024
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