A novel series of pyrazoline and thiazole derivatives incorporating 2-pyrazolin-5-one moiety were synthesized starting from α,β-unsaturated ketones under the effect of hydrazine derivatives and thiosemicarbazide. The obtained pyrazolines 4a, 4b were treated with different reagents to afford N-substituted pyrazolines 5a, 5b, 6a, 6b, 7a, 7b, 8a, 8b. N-Thiocarbamoyl pyrazolines 12a, 12b were cyclized using phenacyl bromide, 2,3-dichloroquinoxaline, and monochloroacetic acid afforded the novel pyrazolinyl thiazoles 13a, 13b, 14a, 14b, 15a, 15b, 16a, 16b, 16c, 16d, 16e, 16f. The newly synthesized compounds were characterized by analytical and spectral data.

In the title compound, C22H18ClN3O, the carbazole ring system is essentially planar (r.m.s deviation = 0.003 A ° ), and makes a dihedral angle of 9.01 (8) with the plane of the chlorophenyl ring. In the crystal, neighbouring molecules are linked into centrosymmetric R2 2(8) dimers by pairs of N— H  O interactions and into a three-dimensional network by C—H   interactions. The dimers are arranged into layers parallel to (010

Porous Anodic Alumina (PAA) membranes have been fabricated from pure and doped aluminum films (Pure Al, Al-0.5wt.% Cu and Al-1wt.%Si) by the one-step anodization method at room temperature. Formation of the PAA has been performed by three different electrolytes, namely: sulfuric (1 M), oxalic (0.3 M) and phosphoric (0.75 M) acids. For this purpose, potentiostatic anodization in a two-electrode cell configuration has been carried out. High quality alumina with straight pores have been obtained starting from pure aluminum metal films. It is found that, different types of branched structures are formed by aluminum films doped with impurities such as Si and Cu. The relationship between the electrochemical current response and the obtained pore architectures are discussed. Oxide formation rates, barrier layer thickness, vertical and horizontal inter-pore distances are investigated. The present synthesized templates have a large surface area make it one of the mostpopular nanomaterial with applications across a gamut of areas including, energy storage, sensors and biosensors.

Porous Anodic Alumina (PAA) membranes have been fabricated from pure and doped aluminum films (Pure Al, Al-0.5wt.% Cu and Al-1wt.%Si) by the one-step anodization method at room temperature. Formation of the PAA has been performed by three different electrolytes, namely: sulfuric (1 M), oxalic (0.3 M) and phosphoric (0.75 M) acids. For this purpose, potentiostatic anodization in a two-electrode cell configuration has been carried out. High quality alumina with straight pores have been obtained starting from pure aluminum metal films. It is found that, different types of branched structures are formed by aluminum films doped with impurities such as Si and Cu. The relationship between the electrochemical current response and the obtained pore architectures are discussed. Oxide formation rates, barrier layer thickness, vertical and horizontal inter-pore distances are investigated. The present synthesized templates have a large surface area make it one of the mostpopular nanomaterial with applications across a gamut of areas including, energy storage, sensors and biosensors.

Porous Anodic Alumina (PAA) membranes have been fabricated from pure and doped aluminum films (Pure Al, Al-0.5wt.% Cu and Al-1wt.%Si) by the one-step anodization method at room temperature. Formation of the PAA has been performed by three different electrolytes, namely: sulfuric (1 M), oxalic (0.3 M) and phosphoric (0.75 M) acids. For this purpose, potentiostatic anodization in a two-electrode cell configuration has been carried out. High quality alumina with straight pores have been obtained starting from pure aluminum metal films. It is found that, different types of branched structures are formed by aluminum films doped with impurities such as Si and Cu. The relationship between the electrochemical current response and the obtained pore architectures are discussed. Oxide formation rates, barrier layer thickness, vertical and horizontal inter-pore distances are investigated. The present synthesized templates have a large surface area make it one of the mostpopular nanomaterial with applications across a gamut of areas including, energy storage, sensors and biosensors.

Porous Anodic Alumina (PAA) membranes have been fabricated from pure and doped aluminum films (Pure Al, Al-0.5wt.% Cu and Al-1wt.%Si) by the one-step anodization method at room temperature. Formation of the PAA has been performed by three different electrolytes, namely: sulfuric (1 M), oxalic (0.3 M) and phosphoric (0.75 M) acids. For this purpose, potentiostatic anodization in a two-electrode cell configuration has been carried out. High quality alumina with straight pores have been obtained starting from pure aluminum metal films. It is found that, different types of branched structures are formed by aluminum films doped with impurities such as Si and Cu. The relationship between the electrochemical current response and the obtained pore architectures are discussed. Oxide formation rates, barrier layer thickness, vertical and horizontal inter-pore distances are investigated. The present synthesized templates have a large surface area make it one of the mostpopular nanomaterial with applications across a gamut of areas including, energy storage, sensors and biosensors.

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There is a growing demand to find an effective extraction process of sulfated polysaccharides from brown algae to conserve its structure and biological activity. Fucoidan was recovered from Sargassum sp. using a hot buffer extraction process. BoxeBenhken experimental design was evaluated to study different conditions of temperature, pH and buffer: alga ratio on fucoidan yield and its sulfate content. By solving the regression equations and analyzing 3-D plots, the optimum conditions were at extraction temperature 60
C, pH 4.0, and ratio of buffer: alga 10.0 mL/g. Under these conditions, the experimental fucoidan yield, and sulfate content were 19 and 47.6% (w/w), respectively, which were in good agreement with the predicted values. The use of hot buffer extraction was efficient to obtain a high fucoidan yield with maintaining high sulfate contents. Fucoidan preparations showed variations in antioxidant properties using various antioxidant assays. Increasing reducing antioxidant activity and hydroxyl radical scavenging of fucoidan extracts was attributed to increasing total sugars, fucose, and uronic acids. The data obtained suggested that the sulfate groups might act as reductones rather than radical scavengers to contribute to the antioxidant activity of fucoidan. Additionally, proteinaceous and phenolic compounds co-extracted with crude fucoidan contributed to its antioxidant potential. Crude fucoidan demonstrated good emulsion stabilizing capacities, especially with cedar wood oil and xylene. These results suggest the use of the crude fucoidan as a good alternative to many synthetic polymers, as well as other natural polysaccharides, in several applications in the food, pharmaceutical, cosmetic, textile, paper and petroleum industries.

There is a growing demand to find an effective extraction process of sulfated polysaccharides from brown algae to conserve its structure and biological activity. Fucoidan was recovered from Sargassum sp. using a hot buffer extraction process. BoxeBenhken experimental design was evaluated to study different conditions of temperature, pH and buffer: alga ratio on fucoidan yield and its sulfate content. By solving the regression equations and analyzing 3-D plots, the optimum conditions were at extraction temperature 60
C, pH 4.0, and ratio of buffer: alga 10.0 mL/g. Under these conditions, the experimental fucoidan yield, and sulfate content were 19 and 47.6% (w/w), respectively, which were in good agreement with the predicted values. The use of hot buffer extraction was efficient to obtain a high fucoidan yield with maintaining high sulfate contents. Fucoidan preparations showed variations in antioxidant properties using various antioxidant assays. Increasing reducing antioxidant activity and hydroxyl radical scavenging of fucoidan extracts was attributed to increasing total sugars, fucose, and uronic acids. The data obtained suggested that the sulfate groups might act as reductones rather than radical scavengers to contribute to the antioxidant activity of fucoidan. Additionally, proteinaceous and phenolic compounds co-extracted with crude fucoidan contributed to its antioxidant potential. Crude fucoidan demonstrated good emulsion stabilizing capacities, especially with cedar wood oil and xylene. These results suggest the use of the crude fucoidan as a good alternative to many synthetic polymers, as well as other natural polysaccharides, in several applications in the food, pharmaceutical, cosmetic, textile, paper and petroleum industries.