Enhanced cellular uptake by “pharmaceutically oriented devices” of new simplified analogs of Linezolid with antimicrobial activity

Research Abstract

NULL

Research Authors
Ortensia Ilaria Parisi, Marco Fiorillo, Anna Caruso, Anna Rita Cappello, Carmela Saturnino, Francesco Puoci, Antonella Panno, Vincenza Dolce, Hussein El-Kashef, Maria Stefania Sinicropi
Research Department
Department of chemistry
Research Journal
International Journal of Pharmaceutics
Research Member
Hussein Mohamed salama El-kashef
Research Pages
163– 170
Research Publisher
NULL
Research Rank
1
Research Vol
461
Research Website
https://www.sciencedirect.com/science/article/pii/S0378517313010429
Research Year
2014

Access to Polycyclic Derivatives by Triflate-Catalyzed Intramolecular Hydroarylation.

Research Abstract

NULL

Research Authors
Bastien Cacciuttolo, Sophie Poulain-Martini, Fabien Fontaine-Vive, Mahmoud Ali Hussein Abdo, Hussein El-Kashef, and Elisabet Duñach.
Research Department
Department of chemistry
Research Journal
Eur. J. Org. Chem.
Research Member
Hussein Mohamed salama El-kashef
Research Pages
7458–7468
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
https://onlinelibrary.wiley.com/doi/epdf/10.1002/ejoc.201402972
Research Year
2014

Organic matrices, ionic liquids, and organic matrices@nanoparticles assisted laser desorption/ionization mass spectrometry

Research Abstract

The applications of organic matrices for matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS) are reviewed. Recent advances of MALDI-MS using organic matrices, including the applications of ionic liquids matrices (ILMs) and organic matrices modified/conjugated nanoparticles, are covered. Organic matrices are applied for many other applications such as derivatization or capping agents of nanoparticles, eluent for chromatography, internal standard for quantitative analysis and as reagents for the synthesis of eco-friendly solvents (ILMs). Within the field of nanotechnology, organic matrices@nanoparticles have a dominant position, and the last decade has seen remarkable growth for these hybrid materials. Selection of the optimum organic matrices is paramount important and critical for the analysis using MALDI-MS. Factors such as additives, instrument set up and sample preparation affect greatly the results of analysis. Advanced techniques using organic matrices are also highlighted.

Research Authors
Hani NasserAbdelhamid
Research Department
Department of chemistry
Research Journal
TrAC Trends in Analytical Chemistry
Research Member
Hani Nasser Abdelhamid
Research Pages
PP.68-98
Research Publisher
NULL
Research Rank
1
Research Vol
Vol.89
Research Website
https://doi.org/10.1016/j.trac.2017.01.012
Research Year
2017

Template-free and room temperature synthesis of hierarchical porous zeolitic imidazolate framework nanoparticles and their dye and CO2 sorption

Research Abstract

Hierarchical porous zeolitic imidazolate framework ZIF-8 nanoparticles have been synthesized using zinc nitrate, 2-methylimidazole (Hmim), and sodium hydroxide. Zinc hydroxide nitrate nanosheets were formed as intermediates that further transformed to hierarchical porous ZIF-8 after the addition of Hmim. These intermediates serve as in situ sacrificial templates and promote the formation of hierarchical porous ZIF-8 without the need for any other templates. The surface area and mesoporosity of the materials can be tuned by adjusting the concentration of NaOH. This method offers a fast and template-free approach for the synthesis of pure hierarchical porous ZIF-8 at room temperature with tunable porosity. The approach has been applied to synthesize two-dimensional ZIF leaf-like materials, ZIF-L. The synthesis of ZIF-8 and ZIF-L can be scaled up with high yields (>80%). The resulting ZIF-8 and ZIF-L materials show very good CO2 sorption properties. ZIF-8 nanoparticles show fast (<5 min), selective, and high efficiency (>95%) uptake of methyl blue in aqueous solution both without and in the presence of other dyes. The results open a new avenue for the understanding of the self-assembly and the formation of hierarchical porous ZIFs.

Research Authors
Hani Nasser Abdelhamid and Xiaodong Zou
Research Department
Department of chemistry
Research Journal
Green Chemistry
Research Member
Hani Nasser Abdelhamid
Research Pages
PP.1074-1084
Research Publisher
NULL
Research Rank
1
Research Vol
Vol.20
Research Website
NULL
Research Year
2018

Crystal structure of (E)-4-{[2-(2,4-dinitrophenyl)hydrazin-1-ylidene]methyl}-3-methyl-1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole

Research Abstract

NULL

Research Authors
Joel T. Mague, Shaaban K. Mohamed, Mehmet Akkurt, Hussein M. S. El-Kashef and Mustafa R. Albayati,
Research Department
Department of chemistry
Research Journal
Acta Cryst. E70
Research Member
Hussein Mohamed salama El-kashef
Research Pages
o1246–o1247
Research Publisher
NULL
Research Rank
1
Research Vol
70 (Pt12)
Research Website
http://journals.iucr.org/e/issues/2014/12/00/is5380/index.html
Research Year
2014

Crystal structure of 2-[12-methyl-14-phenyl-10,13,14,16-tetraazatetracyclo-[7.7.0.02,7.011,15]hexadeca-
1(16),2,4,-6,9,11(15),12-heptaen-8-ylidene]-propandinitrile

Research Abstract

NULL

Research Authors
Joel T. Mague, Shaaban K. Mohamed, Mehmet Akkurt, Hussein M. S. El-Kashef and Mustafa R. Albayati
Research Department
Department of chemistry
Research Journal
Acta Cryst. E70
Research Member
Hussein Mohamed salama El-kashef
Research Pages
o1244–o1245
Research Publisher
NULL
Research Rank
1
Research Vol
70(Pt 12)
Research Website
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257392/
Research Year
2014

Indenopyrazole Oxime Ethers: Synthesis and 1-Adrenergic Blocking Activity

Research Abstract

NULL

Research Authors
Tommaso Angelone,, Anna Caruso, Christophe Rochais, Angela Maria Caputo, Maria Carmela Cerra, Patrick Dallemagne,, Elisabetta Filice, David Genest, Teresa Pasqua, Francesco Puoci, Carmela Saturnino, Maria Stefania Sinicropi, and Hussein El-Kashef.
Research Department
Department of chemistry
Research Journal
Eur. J. Med. Chem.
Research Member
Hussein Mohamed salama El-kashef
Research Pages
672-681
Research Publisher
NULL
Research Rank
1
Research Vol
92
Research Website
https://ac.els-cdn.com/S0223523415000574/1-s2.0-S0223523415000574-main.pdf?_tid=336b3158-e45f-42e7-bc53-d6ce27f17189&acdnat=1524156786_ba725c0833aa0637f621134217b8206f
Research Year
2015

3-(Dipropylamino)-5-hydroxybenzofuro[2,3-f]quinazolin-1(2H)-one (DPA-HBFQ-1) plays an inhibitor role on
breast cancer cell growth and progression.

Research Abstract

NULL

Research Authors
Rizza P, Pellegrino M, Caruso A, Iacopetta D, Sinicropi MS, Rault S, Lancelot JC, El-Kashef H, Lesnard A, Rochais C, Dallemagne P, Saturnino C, Giordano F, Catalano S, and Sebastiano Andò.
Research Department
Department of chemistry
Research Journal
Eur. J. Med. Chem
Research Member
Hussein Mohamed salama El-kashef
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
https://ac.els-cdn.com/S022352341530341X/1-s2.0-S022352341530341X-main.pdf?_tid=241f0820-0b5f-46cb-b139-911f7e0d5acd&acdnat=1524156272_19a60f591996356893ee69ee05d7a64d
Research Year
2016

Synthesis, Anti-inflammatory and Antibacterial Activities of Novel Pyrazolo[4,3-g]pteridines.

Research Abstract

NULL

Research Authors
Shawkat Ahmed Abdel-Mohsen, Talaat Ibrahim El-Emary, and Hussein Salama El-Kashef.
Research Department
Department of chemistry
Research Journal
Chem. Pharm. Bull.
Research Member
Hussein Mohamed salama El-kashef
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
https://www.jstage.jst.go.jp/article/cpb/64/5/64_c16-00044/_article
Research Year
2016

Synthesis and functionalization of some new
pyridazino[4,5-b]indole derivatives

Research Abstract

NULL

Research Authors
Ibrahim Radini,
Hussein El-Kashef,
Norbert Haider,
and Abdel-Rahman Farghaly*
Research Department
Department of chemistry
Research Journal
ARKIVOC
Research Member
Hussein Mohamed salama El-kashef
Research Pages
NULL
Research Publisher
NULL
Research Rank
1
Research Vol
NULL
Research Website
https://www.arkat-usa.org/get-file/57803/
Research Year
2016
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