Abstract: A series of new 2-pyrazoline analogues was synthesized. The structures of the synthesized compounds were elucidated by the analytical and spectroscopic data. Some selected compounds were screened for the anti-inflammatory activity by using the animal model of carrageenan-induced paw edema in mice. Additionally, the analgesic and acute toxicity of these compounds were evaluated and exhibited reasonable results. The anti-oxidant and anti-inflammatory effects of these compounds were established by measuring the contents of malondialdehyde (MDA), reduced glutathione (GSH), nitric oxide (NO), and tumor necrosis factor alpha (TNF-α) in the edema paw tissue. The results revealed that compounds 5, 6, 7, and 15 could be recognized as potential multi-potent anti-inflammatory agents.

Abstract: Nonclassical effects are investigated in a system formed by two quantum wells, each of which is inside an open cavity. The cavities are spatially separated, linked by a fiber, and filled with a linear optical medium. Based on Husimi distributions (HDs) andWehrl entropy, we explore the effects of the physical parameters on the generation and the robustness of the mixedness and HD information in the phase space. The generated quantum coherence and the HD information depend crucially on the cavity-exciton and fiber cavity couplings as well as on the optical medium density. The HD information and purity are lost due to the dissipation. This loss may be inhibited by increasing the optical susceptibility as well as the couplings of the exciton-cavity and the fiber-cavity. These parameters control the regularity, amplitudes, and frequencies of the generated mixedness.

We explore two open cavity-qubit systems linked via an optical fiber. The generation of non-local correlations (NLCs) between the two qubits, via skew-information and Bell-function, are investigated under the effects of the physical parameters of the initial state and the interaction couplings of the cavity-qubit and the cavity-fiber and the environment. It is found that the robustness and the generation of the NLCs depend on the physical parameters. Under the condition that the cavity-qubit couplings is much smaller than the cavity-fiber coupling, the regularity of the growth and the oscillations of the NLCs are enhanced and are more robust

We explore the quantum correlations (QCs) of two non-interacting two-level systems (qubits). Each qubit is embedded in an open cavity, the cavities are linked by an optical fiber and leak photons to the exter- nal environment. The quantum correlations are investigated via three different quantifiers (measurement- induced nonlocality, geometric quantum discord and negativity) under the effects of the coupling of the qubit-cavity and the fiber-cavity interactions as well as the cavity dissipations. It is found that the gen- eration of QCs and their sudden birth and death phenomena, depend not only on the qubit-cavity and fiber-cavity couplings, but also on the initial states. The robustness of the QCs against the cavity dissi- pations can be enhanced in the regime of the ultra-strong cavity-fiber coupling. We convey that it is possible to control the quantum correlations, as well as to reduce the effect of cavity dissipation.

We explore the quantum correlations (QCs) of two non-interacting two-level systems (qubits). Each qubit is embedded in an open cavity, the cavities are linked by an optical fiber and leak photons to the exter- nal environment. The quantum correlations are investigated via three different quantifiers (measurement- induced nonlocality, geometric quantum discord and negativity) under the effects of the coupling of the qubit-cavity and the fiber-cavity interactions as well as the cavity dissipations. It is found that the gen- eration of QCs and their sudden birth and death phenomena, depend not only on the qubit-cavity and fiber-cavity couplings, but also on the initial states. The robustness of the QCs against the cavity dissi- pations can be enhanced in the regime of the ultra-strong cavity-fiber coupling. We convey that it is possible to control the quantum correlations, as well as to reduce the effect of cavity dissipation.

This paper deals with the numerical solutions and convergence analysis for general singular Lane–Emden type models of fractional order, with appropriate constraint initial conditions. A modified reproducing kernel discretization technique is used for dealing with the fractional Atangana–Baleanu–Caputo operator. In this tendency, novel operational algorithms are built and discussed for covering such singular models in spite of the operator optimality used. Several numerical applications using the well-known fractional Lane–Emden type models are examined, to expound the feasibility and suitability of the approach. From a numerical viewpoint, the obtained results indicate that the method is intelligent and has several features stability for dealing with many fractional models emerging in physics and mathematics, using the new presented derivative.

In this paper, we analyze the dynamics of non-local correlations (NLCs) in an anisotropic two-qubit Heisenberg XYZ model under the effect of the phase damping. An analytical solution is obtained by applying a method based on the eigenstates and the eigenvalues of the Hamiltonian. It is observed that the generated NLCs are controlled by the Dzyaloshinskii–Moriya interaction, the purity indicator, the interaction with the environment, and the anisotropy. Furthermore, it is found that the quantum correlations, as well as the sudden death and sudden birth phenomena, depend on the considered physical parameters. In particular, the system presents a special correlation: the skew-information correlation. The log-negativity and the uncertainty-induced non-locality exhibit the sudden-change behavior. The purity of the initial states plays a crucial role on the generated nonlocal correlations. These correlations are sensitive to the DM interaction, anisotropy, and phase damping.

The intrinsic decoherence effect for two qubits interacting with a coherent field, under the dipoledipole interaction and two-photon resonance, is analytically described. We investigate numerically the population inversion and the quantum coherence. The results show that the generated mixture entropy and the entanglement negativity, can be enhanced and protected by the dipole-dipole interaction and by reducing the initial coherent field intensity. In particular, we find that, the collapses and revivals of the population inversion present high sensitivity to these physical parameters. The nonlinearity of the two-photon processes leads to a generation of a strong two-qubit entanglement. This generated entanglement depends on the initial coherent field intensity, the dipole-dipole interaction and the intrinsic decoherence.

The intrinsic decoherence effect for two qubits interacting with a coherent field, under the dipoledipole interaction and two-photon resonance, is analytically described. We investigate numerically the population inversion and the quantum coherence. The results show that the generated mixture entropy and the entanglement negativity, can be enhanced and protected by the dipole-dipole interaction and by reducing the initial coherent field intensity. In particular, we find that, the collapses and revivals of the population inversion present high sensitivity to these physical parameters. The nonlinearity of the two-photon processes leads to a generation of a strong two-qubit entanglement. This generated entanglement depends on the initial coherent field intensity, the dipole-dipole interaction and the intrinsic decoherence.

In this paper, a nonlinear fractional emerging telecommunication model with higher– order dispersive cubic–quintic is studied by using two recent computational schemes. This kind of model is arising in many applications such as machine learning and deep learning, cloud computing, data science, dense sensor network, artificial intelligence convergence, integration of Internet of Things, self–service IT for business users, self-powered data centers, and dense sensor networks (DSNs) that is used in the turbine blades monitoring and health monitoring. Two practical algorithms (modified Khater method and sech–tanh functions method) are applied to higher–order dispersive cubic–quintic nonlinear complex fractional Schro¨ dinger (NLCFS) equation. Many novel traveling wave solutions are constructed that do not exist earlier. These solutions are considered as the icon key in the emerging telecommunication field, were they able to explain the physical nature of the waves spread, especially in the dispersive medium. For more illustration, some attractive sketches are also depicted for the interpretation physically of the achieved solutions.