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The Scientific Conference of the Pharmacology Department, Faculty of Pharmacy on Tuesday, April 29, 2025.

By the will of Allah, the scientific conference of the Pharmacology at the Faculty of Pharmacy will be held on Tuesday, April 29, 2025, at 11:00 AM. The conference will take place in the Department Council, 5th floor, Building (A).

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خبر عام

Impact of oil type on the development and oral bioavailability of self-nanoemulsifying drug delivery systems containing simvastatin

Research Abstract

The aim of this work is to develop and evaluate self‑nanoemulsifying drug delivery systems (SNEDDS) containing simvastatin to increase its oral bioavailability. Formulation EO 5 (Ethyl oleate 9.3% w/w: Tween 80 49.4% w/w: Propylene glycol 39.3% w/w) and Formulation CL 14 (Clove oil 54.3% w/w: Tween 80 34.4% w/w: Transcutol‑P 9.3% w/w) were thoroughly studied. They showed emulsification time less than 1 min, droplet size in the nanometric range, and almost a complete drug release after 2 h. The in‑vitro dissolution profile of both formulations was found to be significant in comparison to the pure drug in pH 1.2 and 7.4 buffers (P < 0.0001). Furthermore, they demonstrated superior anti‑hyperlipidemic activity in comparison to simvastatin suspension (10 mg/kg/day). In order to investigate the impact of oil type on oral bioavailability, the selected formulations have been examined in terms of the in‑vivo pharmacokinetic study, and formulation EO 5 was found to have higher bioavailability. After oral administration of a single dose (40 mg/kg) of simvastatin‑loaded SNEDDS (CL14 and EO 5), a 1.5‑fold and 1.95‑fold increase in bioavailability were observed, respectively, as compared to simvastatin suspension. Hence, the results indicated that the developed SNEDDS could enhance the therapeutic efficacy and oral bioavailability of simvastatin.

Research Authors
Aya Hamdy, Mahmoud El-Badry, M. Fathy & Ahmed M. El-Sayed
Research Date
Research Department
Research File
Research Journal
Scientific reports
Research Publisher
Springer nature
Research Rank
Q2
Research Vol
14:22584
Research Website
https://www.nature.com/srep/
Research Year
2024

Announcement for fifth-year Pharm D students: Practical exam for the optional course (Computer-aided Drug Design) will be held.

The practical exam for the elective course
"Computer-Aided Drug Design" for 5th-Year Pharm D students will be held in the computer labs
for Group (A) and Group (B) as follows:

Day

Date

Group

Time

Monday

28/04/2025

Group (A)

12:00 PM

Tuesday

29/04/2025

Group (B)

12:00 PM

All students must attend according to their assigned group and time.
No makeup exam will be given without an officially approved excuse.

اعلان لطلاب الفرقة الخامسة فارم دى سوف يعقد امتحان العملي  لمقرر الاختياري (تصميم الدواء بواسطة الحاسوب)

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إعلانات الطلاب

Announcement for First-Year Pharm D and Clinical Pharmacy Students: The second-term mid-term exam and the theoretical and practical exam for the course "Pharmaceutical Organic Chemistry-2" will be held on Saturday, April 26, 2025.

The department announces that the second mid-term exam and the practical theory exam will be held on Saturday, April 26th, from 11:30 AM to 12:30 PM.

Please make sure to attend on time, as the exam will not be repeated.

Venue: Hall 2, beneath Lecture Hall B

Course Content for the mid-term Exam (10 Marks):

  • Prof. Dr. Samia Galal Ahmed's section: “Aldehydes and Ketones” – Lectures 1 and 2
  • Prof. Dr. Ola Ibrahim Abdel Razek's section: “Aliphatic and Aromatic Amines” – Lectures 1 and 2

Course Content for the Practical Theory Exam (15 Marks):

  • All practical sessions
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قسم الكيمياء العضوية

Announcement for First-Year, Clinical Pharmacy, and National University Students: The second-term mid-term exam and the theoretical and practical exam for the course "Pharmaceutical Organic Chemistry-1" will be held on Sunday, May 4, 2025.

The department announces that the second mid-term exam and the second practical theory exam for the course Pharmaceutical Organic Chemistry - 1 (offered course) will be held on Sunday, May 4th, 2025, from 11:30 AM to 12:30 PM.

Please make sure to attend on time, as the exam will not be repeated.

Exam Venues:

  • Pharm D : Hall 1
  • Pharm D National University: Hall 2
  • Pharm D Clinical: Department Lecture Hall

 

اعلان لطلاب الفرقة الأولى وصيدلة اكلينيكية والجامعة الأهلية سوف يعقد امتحان اعمال السنة الثانى وامتحان نظري العملي لمقرر كيمياء عضوية صيدلية-1 يوم الأحد 4 مايو  2025

 

 

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قسم الكيمياء العضوية

Announcement for National University First-Year Students: The practical exam for the course Pharmacognosy-1 will be held on Saturday, April 26, 2025.

The department announces that the second mid-term exam and the second practical theory exam for the course Pharmaceutical Organic Chemistry - 1 (offered course) will be held on Sunday, May 4th, 2025, from 11:30 AM to 12:30 PM.

Please make sure to attend on time, as the exam will not be repeated.

Exam Venues:

  • Pharm D : Hall 1
  • Pharm D National University: Hall 2
  • Pharm D Clinical: Department Lecture Hall

 

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خبر عام

Announcement for First-Year Pharm D Students: The practical exam for the course Pharmacognosy -1 will be held on Monday, April 28, 2025.

The Practical Exam for First-Year Students in the course Pharmacognosy (1) will be held on:

? Monday, April 28th, 2025
? Time: From 8:30 AM to 10:00 AM
? Location: Department Laboratories

Students will be distributed as follows:

Lab

Floor

Student Numbers

Examples of Names

Lab (A)

4th Floor

From 2241002 to 2241038

Abanoub Nasser Ibrahim – Joey Mokhtar Roshdy

Lab (B)

4th Floor

From 2241040 to 2241070

Habiba Sayed Ahmed – Sohaila Khaled Ali Mohamed

Lab (C)

4th Floor

From 2241073 to 2241111

Shahenaz Mohamed Ahmed Othman – Mohamed Yassin Mohamed

Lab (D)

4th Floor

From 2241112 to 2241146

Mahmoud Abdelrahman Abdelrahman Mohamed Abdelkader

Lab (B)

3rd Floor

From 2231005 to 2231110

Ahmed Fawzy Abdel-Aal – Mohamed Gamal Mohamed

? Note:

  • All students must attend in their assigned lab.
  • The exam will not be repeated for any student who is absent without an officially accepted excuse by the faculty administration.
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إعلانات الطلاب
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