Pollution with heavy metals is a common problem worldwide that affects the growth of important crops and human health due to the consumption of contaminated crops. In the recent study, a set of 103 diverse spring wheat genotypes were evaluated for their tolerance to two important metals (lead and tin). The effect of these metals on kernel traits was measured to select tolerant and high-yielding genotypes. A great reduction in kernel length, kernel diameter, kernel width, and thousand kernel weight were found due to the effect of both metals. However, a highly significant correlation between the studied kernel traits was found suggesting their efficiency to indirectly select high yielding genotypes under heavy metals stress. In addition, the effect of the studied heavy metals on the physiological process was investigated and different responses to each metal were found suggesting that there are two different tolerant 

Heavy metal pollution is considered to be a major constraint of the ecosystem in current times. Heavy metals present in the earth’s crust naturally. The intoxication emerges when they are accumulated above the threshold into the environment via natural and/or anthropogenic activities, modern industrialization and some agricultural practices. Large areas of land have been polluted with heavy metals owing to the extensive application of pesticides, fertilizers, municipal and compost wastes, and also due to heavy metal release from smelting industries and metalliferous mines. Heavy metals potentially affect plant growth, metabolism and ionic status. Modification of the oxidative status of the cells is the predominant effect of heavy metals via excessive reactive oxygen species (ROS). Moreover, once inside the cells, heavy metals deregulate the defense components and homeostasis between the production of ROS and

The purpose of this paper is to introduce a new extension of the generalized admissible S-algorithm
for approximating common fixed point of three multivalued mappings satisfying two general
classes of contraction conditions in a uniformly convex Banach space endowed with a graph. As
an application of our result we establish the solution of image recovery problem in Hilbert space
setting.

The essential protein element of spider silk ‘spidroin’was used to assess its impact on the wound-healing process.

Methods:

Spidroin nanoparticles (NPs) were prepared using poly (lactic-co-glycolic acid) polymer (PLGA/spidroin NPs) at different weight ratios (5: 1, 10: 1, 15: 1) and were in vitro characterized. The optimized NPs were tested in vitro for release and antibacterial activity. To assess wound-healing effects, NPs were topically applied on surgically induced injuries in Allolobophora caliginosa earthworms as a robust human skin model.

Results:

Optimized NPs (173±3 nm) revealed considerable antibacterial effect against Staphylococcus aureus and Escherichia coli. After 4 days of NPs application on wounds, macroscopical and histological examinations revealed a significant reduction in wound and re-epithelialization times.

Background: This paper showed the synthetic capability of the indolo[2,3-b]quinoxaline nucleus to be provided as an excellent precursor for the synthesis of various heterocyclic compounds. These synthetic routes proceed via the formation of 3-(6H-indolo[2,3-b]quinoxalin-6-yl) propane hydrazide (2). The carbohydrazide 2 and its reactions with different reagents give five and six-membered rings, such as 1,3,4-thiadiazole, 1,3,4- oxadiazole, 1,2,4-triazole, and 1,2,4-triazine.

Methods: All chemicals used in the current study were of analytical grade. Melting points were determined using an APP Digital ST 15 melting point apparatus and were uncorrected. FT-IR spectra were recorded on a Pye- Unicam SP3-100 and Shimadzu-408 spectrophotometers in KBr pellets and given in (cm^-1) KBr. The NMR spectra were detected by a Bruker AV-400 spectrometer (400 MHz for ¹H, 100 MHz for ¹³C and 40.55 MHz for ¹⁵N), Institute of Organic Chemistry, Karlsruhe, Germany. Chemical shifts were expressed as δ (ppm) with TMS as an internal reference. Mass spectrometry was provided on a Varian MAT 312 instrument in EI mode (70 eV).

Results: The target compounds were obtained, and their structures were completely elucidated by various spectral and elemental analyses (Ft-IR, ¹H-NMR, ¹³C-NMR, and mass spectrometry).

Conclusion: The current work showed a view of the reactivity of the carbohydrazide group. The carbohydrazide 2 was obtained from the hydrazinolysis of carboethoxy compound 1 and exploited as a key intermediate to synthesize heterocyclic compounds with different rings.