Some new azo-dye sulphonamides based on 5-sulphonylpiperidino and/or (morpholino)-8-hydroxyquinoline (1,1') have been synthesized by diazotization of 4-aminobenzene 4'-(substituted heterocyclo-)-sulphonamide derivatives and coupling with 5-sulphonylpiperidino-(morpholino)-8-hydroxyquinoline in acid medium, affording the corresponding substituted 7-f4-azo-4'-substituted benzene sulphonamido]-5-sulphonyl piperidino-(morpholino)-8-hydroxyquinoline (2a-h, 2'a-h) as ligands. Interaction of these ligands with metal salts Hg2+, Cu2+ and Fe3+ in solution afforded the corresponding metal chelates (3a-c-10a-c). All the synthesized compounds have been screened in vitro for their antibacterial activities. The synthesized compounds were investigated on the basis of microanalytical data, IR, UV and [1H]-NMR spectroscopy

Some new azo-dye sulphonamides based on 5-sulphonylpiperidino and/or (morpholino)-8-hydroxyquinoline (1,1') have been synthesized by diazotization of 4-aminobenzene 4'-(substituted heterocyclo-)-sulphonamide derivatives and coupling with 5-sulphonylpiperidino-(morpholino)-8-hydroxyquinoline in acid medium, affording the corresponding substituted 7-f4-azo-4'-substituted benzene sulphonamido]-5-sulphonyl piperidino-(morpholino)-8-hydroxyquinoline (2a-h, 2'a-h) as ligands. Interaction of these ligands with metal salts Hg2+, Cu2+ and Fe3+ in solution afforded the corresponding metal chelates (3a-c-10a-c). All the synthesized compounds have been screened in vitro for their antibacterial activities. The synthesized compounds were investigated on the basis of microanalytical data, IR, UV and [1H]-NMR spectroscopy

4-Hydroxyacetophenone (1) was reacted with cinnamonitrile derivatives (2-6) to give 3-cyano-4-(substituted phenyl)-6-(p-hydroxyphenyl)-pyridines (7-11). Interaction of compounds 7-9 with 4'-substituted heterocyclo-benzenesulphonyl diazonium chloride gave the corresponding 3-cyano-4-(substituted phenyl)-6-(3'-azobenzene sulphonamido-4'-hydroxyphenyl) pyridines (12-29). The corresponding iron (III) copper (II) and mercury (II) chelates were also prepared in a 1:2 metal-to-ligand ratio. All the synthesized compounds were characterized on the basis of microanalysis, IR and 1H-NMR spectrometry