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Discovery of new pyrimido [5, 4-c] quinolines as potential antiproliferative agents with multitarget actions: Rapid synthesis, docking, and ADME studies
Research Abstract
Research Authors
Mekheimer, Ramadan A and Allam, Samar MR and Al-Sheikh, Mariam A and Moustafa, Moustafa S and Al-Mousawi, Saleh M and Mostafa, Yaser A and Youssif, Bahaa GM and Gomaa, Hesham AM and Hayallah, Alaa M and Abdelaziz, Mohamed and others
Research Date
Research Department
Research Journal
Bioorganic Chemistry
Research Member
Research Vol
121 - 105693
Research Year
2022
Diterpenoids profile of the marine sponge Chelonaplysilla erecta and candidacy as potential antitumor drugs investigated by molecular docking and pharmacokinetic studies
Research Abstract
Research Authors
Abdel-Wahab, Nada Mohamed and Gomaa, Alshymaa Abdel-Rahman and Mostafa, Yaser A and Hajjar, Dina and Makki, Arwa A and Alaaeldin, Eman and Refaat, Hesham and Bringmann, Gerhard and Zayed, Ahmed and Abdelmohsen, Usama Ramadan and others
Research Date
Research Department
Research File
14786419.2022.2063856.pdf
(853.88 KB)
Research Journal
Natural Product Research
Research Member
Research Vol
1--5
Research Year
2022
Antioxidant and Wound Healing Potential of Vitis vinifera Seeds Supported by Phytochemical Characterization and Docking Studies
Research Abstract
Research Authors
Al-Warhi, Tarfah and Zahran, Eman Maher and Selim, Samy and Al-Sanea, Mohammad M and Ghoneim, Mohammed M and Maher, Sherif A and Mostafa, Yaser A and Alsenani, Faisal and Elrehany, Mahmoud A and Almuhayawi, Mohammed S and others
Research Date
Research Journal
Antioxidants
Research Member
Research Vol
11 (5) 881
Research Year
2022
Wound Healing and Antioxidant Capabilities of Zizyphus mauritiana Fruits: In-Vitro, In-Vivo, and Molecular Modeling Study
Research Abstract
Research Authors
Shady, Nourhan Hisham and Soltane, Raya and Maher, Sherif A and Saber, Entesar Ali and Elrehany, Mahmoud A and Mostafa, Yaser A and Sayed, Ahmed M and Abdelmohsen, Usama Ramadan
Research Date
Research Journal
Plants
Research Member
Research Vol
11 (11) 1392
Research Year
2022
Novel indazole derivatives as potent apoptotic antiproliferative agents by multi-targeted mechanism: Synthesis and biological evaluation
Research Abstract
Research Authors
Frejat, Firas Obaid Arhema and Zhai, Hongjin and Cao, Yaquan and Wang, Lihong and Mostafa, Yaser A and Gomaa, Hesham AM and Youssif, Bahaa GM and Wu, Chunli
Research Date
Research Department
Research File
Novel indazole.pdf
(543.19 KB)
Research Journal
Bioorganic Chemistry
Research Vol
126 - 105922
Research Year
2022
Synthesis and Biological Evaluation of Indole-2-Carboxamides with Potent Apoptotic Antiproliferative Activity as EGFR/CDK2 Dual Inhibitors
Research Abstract
Research Authors
Al-Wahaibi, Lamya H and Mostafa, Yaser A and Abdelrahman, Mostafa H and El-Bahrawy, Ali H and Trembleau, Laurent and Youssif, Bahaa GM
Research Date
Research Journal
Pharmaceuticals
Research Vol
15(8) - 1006
Research Year
2022
Design, synthesis, crystal structures and biological evaluation of some 1, 3-thiazolidin-4-ones as dual CDK2/EGFR potent inhibitors with potential apoptotic antiproliferative effects
Research Abstract
Research Authors
Tawfeek, Hendawy N and Hassan, Alaa A and Br{\"a}se, S and Nieger, M and Mostafa, Yaser A and Gomaa, Hesham AM and Youssif, Bahaa GM and El-Shreef, Essmat M
Research Date
Research Journal
Arabian journal of chemistry
Research Vol
(15)11-104280
Research Year
2022
Synthesis of novel amidines via one-pot three component reactions: Selective topoisomerase I inhibitors with antiproliferative properties
Research Abstract
Research Authors
El-Sheref, Essmat M and Tawfeek, Hendawy N and Hassan, Alaa A and Br{\"a}se, S and Elbastawesy, Mohammed AI and Gomaa, Hesham AM and Mostafa, Yaser A and Youssif, Bahaa GM
Research Date
Research Journal
Frontiers in Chemistry
Research Vol
10
Research Year
2022
Metabolomic Profiling, In Vitro Antimalarial Investigation and In Silico Modeling of the Marine Actinobacterium Strain Rhodococcus sp. UR111 Associated with the Soft Coral Nephthea sp.
Research Abstract
Research Authors
Gamaleldin, Noha M and Bahr, Hebatallah S and Mostafa, Yaser A and McAllister, Bryant F and El Zawily, Amr and Ngwa, Che J and Pradel, Gabriele and Hassan, Hossam M and Abdelmohsen, Usama Ramadan and Alkhalifah, Dalal Hussien M and others
Research Date
Research Journal
Antibiotics
Research Member
Research Vol
11(11) 1631
Research Year
2022