Three new phenolic glycosides (1–3) together with nine known ones were isolated from the roots of Tecoma mollis using DPPH radical scavenging bioassay-guided chromatographic separation. The structures of the new compounds were established using extensive spectroscopic data and HR-MS. The antioxidant, COX-2 inhibition, and cytotoxic activities were evaluated for the isolated compounds. Compound 4 displayed the strongest radical scavenging activity relative to ascorbic acid with IC50 8.7 μM. Compounds 5, 6, and 10 showed promising COX-2 inhibitory action, IC50 values of 11.3 μM, 9.4 μM, and 13.4 μM, respectively. All compounds exhibited weak cytotoxic activity against Hela and A549 cancer cell lines.

Three new phenolic glycosides (1–3) together with nine known ones were isolated from the roots of Tecoma mollis using DPPH radical scavenging bioassay-guided chromatographic separation. The structures of the new compounds were established using extensive spectroscopic data and HR-MS. The antioxidant, COX-2 inhibition, and cytotoxic activities were evaluated for the isolated compounds. Compound 4 displayed the strongest radical scavenging activity relative to ascorbic acid with IC50 8.7 μM. Compounds 5, 6, and 10 showed promising COX-2 inhibitory action, IC50 values of 11.3 μM, 9.4 μM, and 13.4 μM, respectively. All compounds exhibited weak cytotoxic activity against Hela and A549 cancer cell lines.

Three new phenolic glycosides (1–3) together with nine known ones were isolated from the roots of Tecoma mollis using DPPH radical scavenging bioassay-guided chromatographic separation. The structures of the new compounds were established using extensive spectroscopic data and HR-MS. The antioxidant, COX-2 inhibition, and cytotoxic activities were evaluated for the isolated compounds. Compound 4 displayed the strongest radical scavenging activity relative to ascorbic acid with IC50 8.7 μM. Compounds 5, 6, and 10 showed promising COX-2 inhibitory action, IC50 values of 11.3 μM, 9.4 μM, and 13.4 μM, respectively. All compounds exhibited weak cytotoxic activity against Hela and A549 cancer cell lines.

Five flavonoidal compounds were successively isolated and identified from the ethanolic extract of the fruits of Faidherbia albida. Two of them were previously isolated from the leaves of Faidherbia albida, such as Rhamnocitrin (F-1) and Quercetin (F-4), the other three are firstly reported for isolation from the fruit, and named Dihydrokaempferol (F-2), Luteolin (F-3) and Rutin (F-5). The structures were identified and confirmed through different spectroscopic methods including 1H-NMR, 13C-NMR and UV spectroscopy, in addition to comparison with authentic samples. Antioxidant activity was determined by the DPPH method revealed that all the tested extracts and fractions exhibited strong antioxidant activity especially the total ethanolic extract, chloroform and ethyl acetate fractions of the fruits.

Five flavonoidal compounds were successively isolated and identified from the ethanolic extract of the fruits of Faidherbia albida. Two of them were previously isolated from the leaves of Faidherbia albida, such as Rhamnocitrin (F-1) and Quercetin (F-4), the other three are firstly reported for isolation from the fruit, and named Dihydrokaempferol (F-2), Luteolin (F-3) and Rutin (F-5). The structures were identified and confirmed through different spectroscopic methods including 1H-NMR, 13C-NMR and UV spectroscopy, in addition to comparison with authentic samples. Antioxidant activity was determined by the DPPH method revealed that all the tested extracts and fractions exhibited strong antioxidant activity especially the total ethanolic extract, chloroform and ethyl acetate fractions of the fruits.

Five flavonoidal compounds were successively isolated and identified from the ethanolic extract of the fruits of Faidherbia albida. Two of them were previously isolated from the leaves of Faidherbia albida, such as Rhamnocitrin (F-1) and Quercetin (F-4), the other three are firstly reported for isolation from the fruit, and named Dihydrokaempferol (F-2), Luteolin (F-3) and Rutin (F-5). The structures were identified and confirmed through different spectroscopic methods including 1H-NMR, 13C-NMR and UV spectroscopy, in addition to comparison with authentic samples. Antioxidant activity was determined by the DPPH method revealed that all the tested extracts and fractions exhibited strong antioxidant activity especially the total ethanolic extract, chloroform and ethyl acetate fractions of the fruits.

Five flavonoidal compounds were successively isolated and identified from the ethanolic extract of the fruits of Faidherbia albida. Two of them were previously isolated from the leaves of Faidherbia albida, such as Rhamnocitrin (F-1) and Quercetin (F-4), the other three are firstly reported for isolation from the fruit, and named Dihydrokaempferol (F-2), Luteolin (F-3) and Rutin (F-5). The structures were identified and confirmed through different spectroscopic methods including 1H-NMR, 13C-NMR and UV spectroscopy, in addition to comparison with authentic samples. Antioxidant activity was determined by the DPPH method revealed that all the tested extracts and fractions exhibited strong antioxidant activity especially the total ethanolic extract, chloroform and ethyl acetate fractions of the fruits.

Eight phenolic compounds were successively isolated and identified from the ethanolic extract of the leaves of Faidherbia albida. Five of them were previously isolated from the genus Acacia, such as β- amyrin (L-1), β-sitosterol (L-2), β-sitosterol-3-O-β-D-glucopyranoside.(L-3), Quercetin (L-5) and Gallic acid (L-6), the other three are firstly reported for isolation from the genus Acacia, and named Rhamnocitrin (L-4), Afzelin (L-7) and (6S, 9S)- Roseoside (L-8). The structures were identified and confirmed through different spectroscopic methods including 1H-NMR, 13C-NMR, HMBC and UV spectroscopy, in addition to comparison with authentic samples. Antioxidant activity was determined by the DPPH method revealed that all the tested extracts and fractions exhibited strong antioxidant activity especially ethyl acetate and aqueous fractions of the leaves.

Eight phenolic compounds were successively isolated and identified from the ethanolic extract of the leaves of Faidherbia albida. Five of them were previously isolated from the genus Acacia, such as β- amyrin (L-1), β-sitosterol (L-2), β-sitosterol-3-O-β-D-glucopyranoside.(L-3), Quercetin (L-5) and Gallic acid (L-6), the other three are firstly reported for isolation from the genus Acacia, and named Rhamnocitrin (L-4), Afzelin (L-7) and (6S, 9S)- Roseoside (L-8). The structures were identified and confirmed through different spectroscopic methods including 1H-NMR, 13C-NMR, HMBC and UV spectroscopy, in addition to comparison with authentic samples. Antioxidant activity was determined by the DPPH method revealed that all the tested extracts and fractions exhibited strong antioxidant activity especially ethyl acetate and aqueous fractions of the leaves.

Eight phenolic compounds were successively isolated and identified from the ethanolic extract of the leaves of Faidherbia albida. Five of them were previously isolated from the genus Acacia, such as β- amyrin (L-1), β-sitosterol (L-2), β-sitosterol-3-O-β-D-glucopyranoside.(L-3), Quercetin (L-5) and Gallic acid (L-6), the other three are firstly reported for isolation from the genus Acacia, and named Rhamnocitrin (L-4), Afzelin (L-7) and (6S, 9S)- Roseoside (L-8). The structures were identified and confirmed through different spectroscopic methods including 1H-NMR, 13C-NMR, HMBC and UV spectroscopy, in addition to comparison with authentic samples. Antioxidant activity was determined by the DPPH method revealed that all the tested extracts and fractions exhibited strong antioxidant activity especially ethyl acetate and aqueous fractions of the leaves.