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Important Announcement For Second-Year Pharm-D Students (General, Clinical, and National University) Regarding the Midterm Examination for the course: Pharmaceutical Organic Chemistry-3
The Research Ethics Committee at the Faculty of Pharmacy Organized a Lecture Entitled: “Biological Waste Management in Healthcare Facilities and Laboratories”
Under the patronage of Prof. Dr. Ahmed El-Menshawy, President of the University, and Prof. Dr. Gamal Badr, Vice President for Postgraduate Studies and Research, and under the supervision of Prof. Dr. Gehan Nabil Fateeh, Dean of the Faculty, Prof. Dr. Dina Fathallah Mohamed, Vice Dean for Postgraduate Studies and Research, and Prof. Dr. Tehani Hassan El-Fahham, Emeritus Professor of Pharmaceutics and Chairperson of the Faculty Research Ethics Committee, and in accordance with the training plan of the Committee, a lecture entitled “Biological Waste Management in Healthcare Facilities and Laboratories” was organized.
The event was attended by Prof. Dr. Noha Nahid Attia, Vice Dean for Community Service and Environmental Development, and Prof. Dr. Gilan Abdel-Razek Abdel-Aleem, Professor of Industrial Pharmacy and Director of the Quality Assurance and Accreditation Unit, along with department heads, faculty members, teaching assistants from various departments, and postgraduate students.
The lecture was delivered by Dr. Ehsan Mohamed Wagih, Lecturer in the Department of Microbiology and Immunology.
The event took place on Thursday, December 4, 2025.
Awareness Seminar Titled: “Connected… but Not Addicted: How to Use the Internet Without Letting It Use Us”
Under the patronage of Prof. Dr. Ahmed Al-Manshawy, President of the University, and Prof. Dr. Mohamed Ahmed Adawy, Vice President of the University for Community Service and Environmental Development, and under the supervision of Prof. Dr. Jihan Nabil Fetih, Dean of the Faculty, and Prof. Dr. Noha Nahidh Atiya, Vice Dean for Community Service and Environmental Development, the Community Service and Environmental Development Sector at the Faculty of Pharmacy organized an awareness seminar entitled:
“Connected… but Not Addicted: How to Use the Internet Without Letting It Use Us.”
The seminar was attended by Prof. Dr. Dina Fathallah Mohamed, Vice Dean for Postgraduate Studies and Research, Prof. Dr. Jilan Abdel-Razek Abdel-Aleem, Professor of Industrial Pharmacy and Director of the Quality Assurance and Accreditation Unit, in addition to a distinguished attendance of heads of departments, faculty members and their assistants, staff members, and students of the Faculty.
The seminar was delivered by Dr. Azza Khairy, PhD in Clinical Psychology and Psychologist at the Mental Health Hospital.
It is worth noting that the seminar shed light on how to use the internet consciously by setting specific time limits, defining clear goals for usage, focusing on purposeful content instead of random browsing, taking regular breaks, limiting device use at certain times, and using selected beneficial applications to reduce distraction.
At the conclusion of the seminar, Prof. Dr. Jihan Nabil Fetih, Dean of the Faculty, presented a certificate of appreciation to Dr. Azza Khairy, the seminar lecturer, in recognition of the valuable lecture and its topic, which concerns all segments of society, as well as the positive interaction of the audience with the seminar.
This event took place on Wednesday, 3/12/2025.
Design, Synthesis, Biological Evaluation, and In Silico Studies of New Nitazoxanide Derivatives: Toward Broad‐Spectrum Antimicrobial Agents
Research Abstract
Nitazoxanide (NTZ), an FDA-approved drug, served as the framework for synthesizing 22 new broad-spectrum antimicrobial agents from 4-aminosalicylic acid via protection–deprotection, Staudinger reduction, Clauson–Kaas pyrrole synthesis, and nucleophilic substitution. These compounds were evaluated for antibacterial, antimycobacterial, and antitrypanosomal activities. Several compounds, particularly 10, 11, 13, and 22, surpassed the antibacterial activity of NTZ and its active metabolite tizoxanide (TIZ) against all tested pathogens, with MICs ranging from 1.025 to 9.81 μM. Compounds 10 and 13 were twice as potent as ciprofloxacin against Klebsiella pneumoniae, while 11 and 17 were equipotent against Pseudomonas aeruginosa (MIC 5.34 μM). Compounds 11 and 14 matched ciprofloxacin against Staphylococcus aureus (MIC 3.20 and 2.98 µM), whereas 13 and 21 were 1.5- and 2.5-fold more potent against Enterococcus faecalis, respectively. Compound 10 outperformed ciprofloxacin against Helicobacter pylori (MIC 1.025 μM). Compounds 6 (MIC 9.46 μM) and 7 (MIC 16.78 μM) outperformed NTZ against Mycobacterium tuberculosis, and compound 3 emerged as a promising antitrypanosomal agent (MICs 2.59–4.73 μg/mL) against six Trypanosoma species. Cytotoxicity and pharmacokinetic studies confirmed the compounds’ favorable drug-like properties and high selectivity. Docking results showed strong binding to key targets like pyruvate ferredoxin oxidoreductase (PFOR), glucosamine-6-phosphate synthase (G6PS), dihydrofolate reductase (DHFR), and ornithine decarboxylase (ODC). Overall, several NTZ derivatives, particularly compounds 3, 6, 10, 11, 13, and 22, showed potent broad-spectrum antimicrobial activity and offer convenient leads for further optimization.
Research Date
Research Department
Research Journal
Archiv der Pharmazie
Research Member
Research Pages
70091
Research Publisher
Wiley Online Library
Research Vol
358
Research Website
https://onlinelibrary.wiley.com/doi/abs/10.1002/ardp.70091
Research Year
2025
Exploring the antitrypanosomal potential of rosemary root endophytic fungi with metabolomic profiling and molecular docking insights
Research Abstract
Nature has been considered an interesting source of secondary bioactive compounds. Plants and their associated endophytes are common sources for these active constituents. Our study demonstrates the metabolomics profiling of the ethyl acetate extracts of three endophytic fungi associated with rosemary roots (Cladosporium spp., Alternaria spp. and Talaromyces spp.) in addition to the in vitro evaluation of the antitrypanosomal potential. The results revealed the presence of 47 metabolites from different chemical classes such as terpenes, phenolics, alkaloids, polyketides, macrolides, and others. Furthermore, the extracts of Cladosporium, Alternaria and Talaromyces exhibited potential inhibitory effects against T. brucei with IC50 values of 1.3, 3.2 and 3.5 µg/mL, respectively. Supporting the study, the identified compounds were docked against two proteins: Rhodesain in complex with a macrolactam inhibitor and ornithine decarboxylase in complex with a c-terminal fragment of antizyme. The docking simulations showed that most of the identified compounds have moderate to comparable docking score (S = − 3.82 to − 6.10 kcal/mol) within rhodesain active site. In addition, they showed weak to moderate docking scores (− 2.33 to − 5.9 kcal/mol) with a differential docking profile within ornithine decarboxylase active site. According to these findings, fungal endophytes associated with rosemary roots can be considered as a promising source of antitrypanosomal bioactive metabolites.
Research Date
Research Department
Research Journal
Scientific Reports
Research Member
Research Pages
16921
Research Publisher
Nature Publishing Group UK
Research Vol
15
Research Website
https://www.nature.com/articles/s41598-025-90304-9
Research Year
2025
Seminar Titled: “Effective Assessment: How to Design Fair and Comprehensive Exams”
Under the patronage of Prof. Dr. Ahmed Al-Manshawy, President of the University, and Prof. Dr. Ahmed Abdel-Mawla, Vice President of the University for Education and Student Affairs, and under the supervision of Prof. Dr. Jihan Nabil Fetih, Dean of the Faculty, Prof. Dr. Hassan Refat Hassan Ali, Vice Dean for Education and Student Affairs, and Prof. Dr. Jilan Abdel-Razek Abdel-Aleem, Professor of Industrial Pharmacy and Director of the Quality Assurance and Accreditation Unit.
Within the framework of the activities of the Quality Assurance and Accreditation Unit at the Faculty, a seminar entitled “Effective Assessment: How to Design Fair and Comprehensive Exams” was organized, attended by Prof. Dr. Dina Fathallah Mohamed, Vice Dean for Postgraduate Studies and Research, Prof. Dr. Noha Nahidh Atiya, Vice Dean for Community Service and Environmental Development, as well as heads of departments, faculty members, and their assistants from all departments.
The lecture was delivered by Prof. Dr. Yasser Ghallab Gouda, Head of the Department of Pharmacognosy and Coordinator of the Clinical Pharmacy Program.
This seminar was held on Monday, 1/12/2025.
Visit of “Students for Egypt” Family to the Faculty of Pharmacy
تUnder the patronage of Prof. Dr. Ahmed Al-Manshawy, President of the University, and Prof. Dr. Ahmed Mohamed Abdel-Mawla, Vice President of the University for Education and Student Affairs, and under the supervision of Prof. Dr. Jihan Nabil Fetih, Dean of the Faculty, Prof. Dr. Hassan Refat Hassan Ali, Vice Dean for Education and Student Affairs, Prof. Dr. Hisham Mohamed Tawfik, Head of the Department of Industrial Pharmacy and Coordinator of Student Activities at the Faculty, and Dr. Shaimaa Ali Abdel-Zaher, Director of the Youth Welfare Administration at the Faculty, and in the presence of Mr. Tarek Sayed, Faculty Secretary, and the student activity specialists at the Faculty Youth Welfare Administration.
Prof. Dr. Jihan Nabil Fetih, Dean of the Faculty, received the “Students for Egypt” Family, headed by Prof. Dr. Madihah Darwish, General Supervisor of Student Activities at the University and General Coordinator of the Family, along with Dr. Haitham Ibrahim, General Director of Central Youth Welfare, and the accompanying delegation.
The delegation toured the art exhibition of student activities at the Faculty. The visit aimed to introduce new students to the Family’s activities and events and to inform them of the opening of registration for joining the Family.
This took place at the Faculty courtyard on Sunday, 30/11/2025.
The Scientific Research Ethics Committee at the Faculty of Pharmacy, Assiut University, presented a scientific seminar titled: "Biological Waste Management in Healthcare Facilities and Laboratories"
In accordance with the training plan of the Research Ethics Committee, the Committee is pleased to invite you to attend a lecture entitled:
“Biological Waste Management in Healthcare Facilities and Laboratories”
to be delivered by
Dr. Ehsan Mohamed Wagih, Lecturer of Microbiology and Immunology.
The lecture will be held on Thursday, December 4, 2025, at 11:00 AM, in the Ceremonial Hall, Building (B).
Announcement of Opening Applications for the Position of Deputy Director of the Quality Assurance and Accreditation Unit at the Faculty
The Faculty announces its intention to assign one of its faculty members to undertake the duties of the position of Deputy Director of the Quality Assurance and Accreditation Unit, provided that the applicant is qualified and experienced, in accordance with the following conditions:
The applicant must be a faculty member currently working at the Faculty and actively participating in quality-related activities at the Faculty.
The applicant must be involved in development and accreditation activities at the Faculty.
Preference will be given to applicants who have obtained training courses in self-evaluation, course specification and reporting, and strategic planning.
The applicant must be known for commitment to professional conduct, awareness of university laws and regulations, and good communication and interaction with colleagues and students in accordance with professional ethics.
The applicant must have the ability to innovate.
Willingness to work long hours throughout the academic year.
Interested applicants are requested to submit their curriculum vitae along with a development vision and a proposed plan for quality assurance at the Faculty during the period from 7/12/2025 to 21/12/2025.