Department Researches & Publications

Department of Pharmaceutical Organic Chemistry

Research

Our researches Plan:

1- Development, study in depth of pharmaceutical organic chemistry and illustration of its synthetic, mechanistic, and industrial applications.

2- Design and synthesis of different classes of compounds such as: Triazoles, benzimidazoles, piperazinedione and thiadiazine derivatives and others A special focus on xanthine and pyridazinone derivatives

3- Structural elucidation of the target compounds utilizing: IR,1H-NMR, MS in addition to elemental analysis Optical Rotation

4- Biological screening: Antimicrobial: antibacterial, antifungal and antituberculosis in addition to anthlemintic activity. Anti-inflammatory, analgesic, antipyretic activities and ulcerogenicity determination. Cardiotonic and hypotensive activities. Hypoglycemic activity. Anticonvulsant activity.

5- Other titles in consideration: Synthesis of new dendimers of potential biological activity. Applications of photochemical reactions for synthesis of certain organic compounds of potential biological activity. Synthesis of some antineurodegenerative compounds. Synthesis of certain nucleosides of potential biological activity. Synthesis of certain adenine derivatives of possible antiviral activity.

# Title Research Year
131 Novel Class of Benzimidazole-Thiazole Hybrids: The Privileged Scaffolds of Potent Anti-Inflammatory Activity with Dual Inhibition of Cyclooxygenase and 15-Lipoxygenase Enzymes 2020
132 Novel Class of Benzimidazole-Thiazole Hybrids: The Privileged Scaffolds of Potent Anti-Inflammatory Activity with Dual Inhibition of Cyclooxygenase and 15-Lipoxygenase Enzymes 2020
133 Novel Class of Benzimidazole-Thiazole Hybrids: The Privileged Scaffolds of Potent Anti-Inflammatory Activity with Dual Inhibition of Cyclooxygenase and 15-Lipoxygenase Enzymes 2020
134 Solvent-Free N‑Formylation: An Experimental Application of Basic Concepts and Techniques of Organic Chemistry
 		2020
135 Solvent-Free N‑Formylation: An Experimental Application of Basic Concepts and Techniques of Organic Chemistry
 		2020
136 Solvent-Free N‑Formylation: An Experimental Application of Basic Concepts and Techniques of Organic Chemistry
 		2020
137 Synthesis and characterization of some new pyridines, thieno[2,3-b] pyridines and pyrido[3',2'-4,5]thieno[3,2-d]pyrimidine-4(3H)-ones bearing styryl moiety 2020
138 Synthesis and characterization of some new S-substituted sulfanylpyridines, thieno[2,3-b]pyridines and related heterocycles 2020
139 Synthesis of some new 1,2-disubstituted-1,2,4-triazolobenzimidazoles with antifungal and anti-inflammatory effects. 2020
140 Aryl Azide-Sulfonamide Hybrids Induce Cellular Apoptosis: Synthesis and Preliminary Screening of Their Cytotoxicity in Human HCT116 and A549 Cancer Cell Lines 2019