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Co-occurrence of carbapenemase and ESBL encoding genes in multidrug-resistant Acinetobacter baumannii isolated from Assiut University Hospitals, Egypt

ملخص البحث
 Carbapenem-resistant Acinetobacter baumannii (CRAB) is an emerging threat to healthcare systems worldwide due to its association with high morbidity, mortality, and, hard-to-treat infections. In Egypt, the prevalence of CRAB infections is rising, particularly in intensive care units (ICUs). This study aimed to investigate the prevalence, and molecular antimicrobial resistance characteristics of CRAB isolates obtained from patients at Assiut University Hospitals in Egypt. 
Methods
 
 Between July 2022 and January 2023, 50 CRAB isolates were identified and tested for antibiotic resistance through normal laboratory procedures. PCR was used to detect important resistance genes: blaOXA-51-like, blaNDM, blaVIM, and blaTEM. 
Results
 
 During the study period, all the isolates were found to be highly resistant to several antibiotics, including carbapenems. Resistance genes such as blaOXA-51-like, blaNDM …
مؤلف البحث
Zainab I Rashed, Amal Mohammed Hosni, Ehsan MW El-Sabaa
تاريخ البحث
مجلة البحث
Microbes and Infectious Diseases
الناشر
Zagazig University, Faculty of Medicine
تصنيف البحث
Q4
سنة البحث
2023