Smart nanohybrid technology with potential advantages to plants has recently been developed for the management of widespread pollution of heavy metals. Herein, we disclose a novel strategy to combat Pb stress in strawberry (Fragaria spp. cv. Fertona) plants through a newly designed nano-based system that conjugates indole acetic acid (IAA) with nanoparticles (NPs) of iron (Fe) and manganese (Mn) micronutrients, forming IAA-Mn₂O₃NPs (IAA-MnNPs) and IAA-Fe₂O₃NPs (IAA-FeNPs) nanocomposites and illuminate the underlying mechanisms involved. NPs were synthesized, yielding cubic Mn₂O₃ NPs (50 nm) and spheric Fe₂O₃ NPs (30-40 nm) evidenced by various characterization techniques. The incorporation of IAA hormone to the surface of NPs was examined using FT-IR spectroscopy. Pb harshly hindered strawberry growth and promoted stress oxidative markers, i.e., MDA and ROS byproducts …