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Comparative study on the effect of antioxidants α-lipoic acid and N-acetyl cysteine on the structure of the renal tubules of diabetic rabbits

Research Abstract

Thirty-two mature male rabbits were used in this study. They were divided into two groups: the control group (n= 8) and the experimental (n= 24) group; the experimental group was injected intraperitoneally with alloxan (180mg/ml/kg body weight). After 3 weeks, this group (diabetic rabbits) was subdivided into three subgroups of eight rabbits each. The first one was left as the untreated diabetic subgroup; rabbits in the second and third subgroups were treated daily for 7 days with ALA and NAC (100 mg/ml/kg body weight), respectively. At the end of the experiment, blood and kidney sections were processed for biochemical and histological studies.

Research Authors
Nasra N Ayuob, Hanem S Abdel-Tawab, S. Ali, Mohammad A Saeed Al-Hegami, Mohamed B Al-Salahy, Hossam Eldin M Omar
Research Date
Research Department
Research Pages
56-66
Research Publisher
Egyptian society of Journal of Histology,
Research Vol
37
Research Year
2014

Oxidant/antioxidant status of erythrocytes from patients falciparum malaria in Yemen and its relation with the intensity of parasitemia

Research Abstract

Oxidant/antioxidant status of erythrocytes from patients falciparum malaria in Yemen and its relation with the intensity of parasitemia

Research Authors
M Al-Salahy, G Abed, A Ahmed Mandour, Bushra Shnawa, Ali Al-Ezzi, M A Mohamed
Research Date
Research Department
Research Journal
Eighth International Conference on Environment and Development in the Arab World Assiut university,,
Research Pages
3-13
Research Publisher
Eighth International Conference on Environment and Development in the Arab World Assiut university,, March,22-24, 2016.
Research Year
2016

Burden of Parasitaemia, Falciparum Malaria and Serum Glucose, Urea and Creatinine among Patients in Abbs (Tehama-Hajjah), Yemen

Research Abstract

Burden of Parasitaemia, Falciparum Malaria and Serum Glucose, Urea and Creatinine among Patients in Abbs (Tehama-Hajjah), Yemen

Research Authors
Mohamed Al-Salahy, G. Abed, Bushra Shnawa, Ali Al-Ezzi, Ahmed Mandour
Research Date
Research Journal
International Journal of Sciences: Basic and Applied Research (IJSBAR),
Research Publisher
International Journal of Sciences: Basic and Applied Research (IJSBAR),
Research Vol
24
Research Year
2015

Effect of the Antioxidant Power Integration of Vitamin E, Selenium and Fenugreek Seeds on Testis of Rat-Treated With Mercuric Chloride

Research Abstract

This study was conducted to evaluate the integrative antioxidant potency of fenugreek seeds suspension powder (FSPS), vitamin E (Vit E), and sodium selenite (Se) against mercuric chloride toxicity (MC) induced oxidative stress in both erythrocytic lysate (EL) and testicular tissue (TT) in Albino male rats. MC was administered orally in drinking water (DW: (50 mg/L= 1/15 of LD50). FSPS (100 g/L soaked for day), Se (2 mg/L) were administered in DW and vit E 150 (mg/100 g diet) mixed in the diet as. The rats were divided into six groups, ten rats each. The first group was control with normal diet and tape water. The second group, consider as positive control, DW containing MC. The third received Vit E (with diet) in addition to MC, the fourth group received MC + Se. The fifth one received MC and FSPS. Finally, the sixth group combination group (COMB group) received DW containing MC, Se in addition to Vit E …

Research Authors
M Bassam Al-Salahy, Hanem S Abdel-Tawab, Ahmed Th A Ibrahim, Sobhy E Hassab El Naby, A Gubran AL-Shabahi
Research Date
Research Department
Research Journal
RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES
Research Pages
1594-1606
Research Publisher
RJPBCS RESEARCH JOURNAL PHARMACEUTICAL, BIOLOGICAL & CHEMICAL SCIENCES
Research Vol
7
Research Year
2016

Effect of seasonal variation on weight composition and gross composition of three Nile fish species.

Research Abstract

Effect of seasonal variation on weight composition and gross composition of three Nile fish species.

Research Authors
K. A Hassan, M. B el-Salahy
Research Date
Research Department
Research Journal
Assiut University, Bulletin of Faculty of Science,
Research Pages
89 – 99.
Research Publisher
Journal of faculty of Science, Assiut University
Research Vol
15
Research Year
1986

Physiological studies on the antioxidant effect of lupine on oxidative stress in liver and muscle in the fish Oreochromis niloticus exposed to neem oil.

Research Abstract

 

This study was designed to investigate the effect of Neem seed oil on the oxidative stress in gills and erythrocytes (EC), after 1, 2 and 3 weeks (W) and to evaluate the antioxidant effect of lupine seed supplementation (LS) in the Nile tilapia   Oreochromis niloticus. Two doses of Neem oil; 1/20 LC50:56 (NO1) and 1/10 LC50:112 PPM (NO2) and three periods of one, two and three weeks were used. Oxidative stress parameter, total peroxide (TP) and antioxidant enzyme activities, catalase (CAT) and superoxide dismutase (SOD) as well as glycemia were measured. NO2 markedly decreased CAT and SOD activities in gills at most periods (52 - 99% and 16 – 52 %, respectively) and in EC (22 - 62 and 48 – 63 %, respectively) in most periods, but NO1 had less effect. In turn, both doses significantly enhanced TP levels in gills and EC. Moreover, hyperglycemia was detected three weeks after control (NO) exposure. LS significantly curtailed or abolished the adverse effect of NO exposure on oxidative and antioxidant parameters in gills and EC. This may be attributed to the hypoglycemic effect of LS as well as its antioxidant efficiency. In conclusion, NO exerts oxidative damage in the fish and LS has an antioxidant potency.

 

Research Authors
M Bassam Al-Salahy, Ashraf A El-Badawi
Research Date
Research Department
Research Journal
Egypt. Ger. Soc. Zool.ISSN 1110-5321 The 19th International Conference 30 April-2May, Faculty of Science, Beni-Sueif University, July 2011.
Research Pages
155 – 187
Research Publisher
Egypt. Ger. Society
Research Vol
63

Prevalence of Plasmodium falciparum in Abs, Hajjah Governorate Northwest Yemen

Research Abstract

Biology Department, Faculty of Science, Soran University, Kurdistan, Iraq 2Biology Department, Faculty of Education, Aden University, Yemen 3Zoology Department, Faculty of Science, Assiut University, Assiut, Egypt 4Parasitology Department, Faculty of Medicine, Assiut University, Assiut, Egypt 5Clinical Pathology Department, Faculty of Medicine, Assiut University, Assiut, Egypt

Research Authors
Bushra Hussain Shnawa, Ali Ali Al-Ezzi, Gamal Hasan Abed, Mohamed Bassam Al-Salahy, Ahmed Mohamed Mandour, Mervat Mohamed
Research Date
Research Department
Research Journal
International Journal of Biosciences
Research Pages
59-71
Research Publisher
Ivyspring International Publisher
Research Vol
9
Research Year
2016

EFFECT OF AQUEOUS EXTRACTS OF GARLIC (ALLIUM SATIVUM) AND ONION (ALLIUM CEPA) ON LIPID AND CARBOHYDRATE METABOLISM IN ALLOXAN-DIABETIC MICE

Research Abstract

Five species of fish were cultured separately in concrete ponds, 840 cubic meters of water per each with a water circulation system. Every species was stocked at a rate of 35000 fish seeds per pond. Species involved were Oreochromis niloticus (0. niloticus), Common carp, Mugel cephalus, Marone labrax and Chrysophrus auratus with, 28. 0 it 0.3, 12.0 土. 20, 30.5 土 0.7, 1.1 土 0.1 and 1.3 土 0.1 initial body wights in grams for each species, respectively. Samples of the same species with the same initial body wights were stocked together at the rate of 7000 fish seeds per species giving a polyculture with stocking density of 35000 per pond, Feeding rate was 574 from the stocked biomass and corrected biweekly according to the recorded average weights using diet containing 26. 57% crude protein. Biweekly samples (to about 1000 fish) were collected from each pond, weighed and the average body weights were 

Research Authors
MB Al-Salahy, AA Hassanien
Research Date
Research Department
Research Pages
32-40
Research Publisher
Assiut Veterinary Medical Journal
Research Vol
30
Research Year
1993

Morphological, immunohistochemical, and biochemical study on the ameliorative efect of gallic acid against bisphenol A induced nephrotoxicity in male albino rats

Research Abstract

This study aimed to determine the effect of gallic acid (GA) on ameliorating bisphenol A (BPA) nephrotoxicity in male rat kidneys. Forty rats were assigned randomly into two groups: control (ten animals) and BPA (40 mg/kg bwt) (thirty animals), the second group was divided into three subgroups: BPA alone, BPA + G50 (50 mg/kg bwt), and BPA + G200 (200 mg/kg bwt). The biochemical analysis included measurements of the contents of nitric oxide, lipid peroxidation, reactive oxygen species, and cytokines (interleukin-1α and interleukin-6) in the kidney. The antioxidant enzymes catalase and superoxide dismutase were also measured in the kidney. Kidney function was assessed by determining uric acid, urea, and creatinine levels. The morphological investigations included hematoxylin and eosin staining for assessing the general histology and determining the glomerular and corpuscular areas, the tubular cell 

Research Authors
Shaimaa M M .Saleh, A Bakr Mahmoud, M Bassam Al‑Salahy, Fatma M M Moustafa
Research Date
Research Department
Research Journal
Scientific Reports
Research Pages
1-20
Research Vol
13

Codimension-1, 2 bifurcation analysis of glucose model with obesity effect

Research Abstract

This work focuses on studying high-codimensional bifurcations in the glucose model with
obesity’s effect. We examine the related dynamical behaviors, taking into account the
risk and adverse health effects associated with obesity’s impact on the glucose model.
Through the application of the normal form method, we demonstrate that the model
exhibits codimension-1 and codimension-2 bifurcations such as saddle node bifurcation
and cusp bifurcation. Additionally, we introduce and prove a theorem that establishes
the presence of Hopf bifurcation in the model. The computation of the first Lyapunov
coefficient is achieved using center manifold theory. To support our theoretical analysis
and showcase the model’s complex dynamical behaviors, including periodic curve families,
we provide numerical simulations. These simulations contribute to understanding
clinical observations regarding the effects of obesity on glucose levels, oscillations and
disorders. Ultimately, this research can aid in the early control of blood glucose levels.

Research Authors
Mahmoud A. Abd Rabo , Gamal M. Mahmoud, Shaban Aly and Tarek M. Abed-Elhameed
Research Date
Research Department
Research Journal
International Journal of Biomathematics (2024) 2450046 (20 pages)
Research Pages
20 pages
Research Publisher
International Journal of Biomathematics (2024) 2450046 (20 pages)
Research Website
World Scientific Publishing Company DOI: 10.1142/S1793524524500463
Research Year
2024
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