Molybdenum (Mo) deficiency is a global problem in acidic soils, limiting plant growth, development and nutrients availability. To address this, we carried out a field study with two treatments i.e. Mo applied (+Mo) and without Mo (-Mo) treatment to explore the effects of Mo application on crop growth and development, microbial diversity, and metabolites variations in maize and soybean cropping systems. Our results indicated that the nutrient availability (N, P, K) was higher under Mo supply, leading to improved biological yield and nutrient uptake efficiency in both crops. Microbial community analysis revealed that Proteobacteria and Acidobacteria were the dominant phyla in Mo treated (+Mo) soils for both maize and soybean. These both phyla accounted together 39.43%, 57.74% in -Mo and +Mo respectively in soybean rhizosphere soil, while 44.51% and 46.64% in maize rhizosphere soil which indicates more variations among the treatments in soybean soil as compared to maize soil. At lower taxonomic, the diverse responses of the genera indicated the specific bacterial community adaptations to fertilization.Candidatus Koribacter and Kaistobacter were commonly significantly higher in both crops under Mo applied circumstances in both cropping systems. These taxa, sharing similar functions, could serve as potential markers for nutrient availability and soil fertility. Metabolite profiling revealed 8 and 10 significantly differential metabolites in maize and soybean, respectively, under +Mo treatment, highlighting the critical role of Mo in metabolite variation. Overall, these findings emphasize the importance of Mo in shaping soil microbial diversity by altering metabolite composition, which in turn may enhance the nutrient availability, nutrient uptake, and plant performance.

Nickel (Ni) is required in trace amounts (less than 500 µg kg−1) to regulate metabolic processes and the immune system and to act as an enzymatic catalytic cofactor. However, it has been recognized as an acute toxic substance. Human nickel exposure occurs through ingestion, inhalation, and skin contact, ultimately leading to respiratory, cardiovascular, and chronic kidney diseases. The nickel concentration in environmental mediums has progres- sively surged to levels as high as 26,000 ppm in soil and 0.2 mg L−1 in water, significantly surpassing the estab- lished threshold limits of 100 ppm for soil and 0.005 ppm for surface water. Nickel is required by various plant species in the range of 0.01–5 µg g−1 (dry weight) to enhance their growth and yield. Nickel toxicity in plants (10–1000 mg kg−1 dry weight mass) leads to down-regulated growth and development, hindered seed germina- tion, chlorosis, necrosis, and disrupted metabolic processes. Nowadays, various remediation approaches are em- ployed to remove heavy metals (especially nickel) including Physicochemical, and biological methods. Physico- chemical methods are not commonly used due to their costly nature and the potential for producing secondary pollutants. On the other hand, bioremediation is an easy-to-handle, efficient, and cost-effective approach, en- compassing techniques such as bioremediation, bioleaching, bioreactors, landforming, and bio-augmentation. However, phytoremediation has become widely utilized for cleaning up contaminated sites. Numerous hyperac- cumulator plants can absorb and store high concentrations of nickel from their surroundings through various mechanisms, thereby helping detoxify nickel-contaminated soils via phytoextraction. Microbe-assisted phytore- mediation further optimizes nickel detoxification by fostering beneficial interactions between microbes and hy- peraccumulator plants, promoting enhanced metal uptake, transformation, and sequestration. Microbe-assisted phytoremediation can be categorized into subtypes: bacterial-assisted phytoremediation, cyanoremediation, my- corrhizal-assisted remediation, and rhizoremediation. This approach leads to a more efficient and sustainable re- mediation of nickel-contaminated environments.

In the present study, nanoceria-decorated MWCNTs (CeNPs@MWCNTs) were synthesized using a simple and inexpensive process. Molnupiravir (MPV) has gained considerable attention in recent years due to the infection of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Since some people infected with COVID-19 experience fever and headaches, paracetamol (PCM) has been prescribed to relieve these symptoms. Therefore, there is an urgent need to monitor and detect these drugs simultaneously in pharmaceutical and biological samples. In this regard, we developed a novel sensor based on nanoceria-loaded MWCNTs (CeNPs@MWCNTs) for simultaneous monitoring of MPV and PCM. The incorporation of CeNPs@MWCNTs electrocatalyst into a glassy carbon microsphere fluorolube oil paste electrode (GCMFE) creates more active sites, which increase the surface area, electrocatalytic 

A new fluorescence sensing approach has been proposed for the precise determination of the anti-cancer drug oxaliplatin (Oxal-Pt). This method entails synthesizing blue-emitting copper nanoclusters (CuNCs) functionalized with bovine serum albumin (BSA) as the stabilizing agent. Upon excitation at 360 nm, the resultant probe exhibits emission at 460 nm. Notably, the fluorescence response of BSA@CuNCs substantially increases upon incubation with Oxal-Pt due to multiple binding interactions between the drug and the fluorescent probe. These interactions involve hydrogen bonding, hydrophobic interaction, and the high affinity between the SH groups (cysteine residues of BSA) and platinum (in Oxal-Pt). Consequently, this interaction induces aggregation-induced emission enhancement (AIEE) of BSA@CuNCs. The probe demonstrates a broad response range from 0.08 to 140.0 μM, along with a low detection