Phytochemical investigation of the leaves of Iris albicans afforded eleven known compounds, including seven isoflavonoids (1–7) and four xanthones (8–11). The structures of these compounds were elucidated on the basis of spectral analysis and literature data. All compounds were reported for the first time from I. albicans. The chemotaxonomic significance of the isolated compounds was summarized.

Salvadora persica L. is a popular chewing stick commonly known as “miswak”. During our ongoing research activities on the chemical constituents of Salvadora persica roots, which is a new sulphur-containing imidazoline alkaloid 1,3-Dibenzyl-4-(1,2,3,4-tetrahydroxy-butyl)-1,3-dihydro-imidazole-2-thione, persicaline, (1) along with five known compounds (2–6) are identified. Compounds (2, 3) were reported for the first time from the family Salvadoraeceae. The structure of the new compound was established by extensive spectroscopic data and HR-MS. The antioxidant activities of the fractions and isolates were evaluated using different in vitro methods, such as DPPH, superoxide anion and nitric oxide radicals scavenging assays. Compound (1) showed a promising antioxidant activity with IC50 0.1, 0.08, and 0.09 µM in the three assays, respectively, comparable to ascorbic acid.

A phytochemical study on the stem bark of Commiphora opobalsamum looking for cytotoxic compounds afforded eleven flavonoids, including six previously undescribed prenylated congeners, comophorin A–E, and comophoroside A. The structures of the isolated compounds were elucidated on the basis of spectroscopic evidences and correlated with known compounds. Isolated compounds were biologically evaluated using in vitro cytotoxicity MTT-based assay against two cancer cell lines; namely human hepato-cellular carcinoma (HepG-2) and human breast adenocarcinoma (MCF-7). Comophoroside A revealed to retain the strongest cytotoxic activity against MCF-7 and HepG-2 cell lines with IC50 values of 8 and 12 μg/mL, respectively.

Three new phenolic glycosides (1–3) together with nine known ones were isolated from the roots of Tecoma mollis using DPPH radical scavenging bioassay-guided chromatographic separation. The structures of the new compounds were established using extensive spectroscopic data and HR-MS. The antioxidant, COX-2 inhibition, and cytotoxic activities were evaluated for the isolated compounds. Compound 4 displayed the strongest radical scavenging activity relative to ascorbic acid with IC50 8.7 μM. Compounds 5, 6, and 10 showed promising COX-2 inhibitory action, IC50 values of 11.3 μM, 9.4 μM, and 13.4 μM, respectively. All compounds exhibited weak cytotoxic activity against Hela and A549 cancer cell lines.

Three new phenolic glycosides (1–3) together with nine known ones were isolated from the roots of Tecoma mollis using DPPH radical scavenging bioassay-guided chromatographic separation. The structures of the new compounds were established using extensive spectroscopic data and HR-MS. The antioxidant, COX-2 inhibition, and cytotoxic activities were evaluated for the isolated compounds. Compound 4 displayed the strongest radical scavenging activity relative to ascorbic acid with IC50 8.7 μM. Compounds 5, 6, and 10 showed promising COX-2 inhibitory action, IC50 values of 11.3 μM, 9.4 μM, and 13.4 μM, respectively. All compounds exhibited weak cytotoxic activity against Hela and A549 cancer cell lines.

Three new phenolic glycosides (1–3) together with nine known ones were isolated from the roots of Tecoma mollis using DPPH radical scavenging bioassay-guided chromatographic separation. The structures of the new compounds were established using extensive spectroscopic data and HR-MS. The antioxidant, COX-2 inhibition, and cytotoxic activities were evaluated for the isolated compounds. Compound 4 displayed the strongest radical scavenging activity relative to ascorbic acid with IC50 8.7 μM. Compounds 5, 6, and 10 showed promising COX-2 inhibitory action, IC50 values of 11.3 μM, 9.4 μM, and 13.4 μM, respectively. All compounds exhibited weak cytotoxic activity against Hela and A549 cancer cell lines.

Three new phenolic glycosides (1–3) together with nine known ones were isolated from the roots of Tecoma mollis using DPPH radical scavenging bioassay-guided chromatographic separation. The structures of the new compounds were established using extensive spectroscopic data and HR-MS. The antioxidant, COX-2 inhibition, and cytotoxic activities were evaluated for the isolated compounds. Compound 4 displayed the strongest radical scavenging activity relative to ascorbic acid with IC50 8.7 μM. Compounds 5, 6, and 10 showed promising COX-2 inhibitory action, IC50 values of 11.3 μM, 9.4 μM, and 13.4 μM, respectively. All compounds exhibited weak cytotoxic activity against Hela and A549 cancer cell lines.

Five flavonoidal compounds were successively isolated and identified from the ethanolic extract of the fruits of Faidherbia albida. Two of them were previously isolated from the leaves of Faidherbia albida, such as Rhamnocitrin (F-1) and Quercetin (F-4), the other three are firstly reported for isolation from the fruit, and named Dihydrokaempferol (F-2), Luteolin (F-3) and Rutin (F-5). The structures were identified and confirmed through different spectroscopic methods including 1H-NMR, 13C-NMR and UV spectroscopy, in addition to comparison with authentic samples. Antioxidant activity was determined by the DPPH method revealed that all the tested extracts and fractions exhibited strong antioxidant activity especially the total ethanolic extract, chloroform and ethyl acetate fractions of the fruits.

Five flavonoidal compounds were successively isolated and identified from the ethanolic extract of the fruits of Faidherbia albida. Two of them were previously isolated from the leaves of Faidherbia albida, such as Rhamnocitrin (F-1) and Quercetin (F-4), the other three are firstly reported for isolation from the fruit, and named Dihydrokaempferol (F-2), Luteolin (F-3) and Rutin (F-5). The structures were identified and confirmed through different spectroscopic methods including 1H-NMR, 13C-NMR and UV spectroscopy, in addition to comparison with authentic samples. Antioxidant activity was determined by the DPPH method revealed that all the tested extracts and fractions exhibited strong antioxidant activity especially the total ethanolic extract, chloroform and ethyl acetate fractions of the fruits.

Five flavonoidal compounds were successively isolated and identified from the ethanolic extract of the fruits of Faidherbia albida. Two of them were previously isolated from the leaves of Faidherbia albida, such as Rhamnocitrin (F-1) and Quercetin (F-4), the other three are firstly reported for isolation from the fruit, and named Dihydrokaempferol (F-2), Luteolin (F-3) and Rutin (F-5). The structures were identified and confirmed through different spectroscopic methods including 1H-NMR, 13C-NMR and UV spectroscopy, in addition to comparison with authentic samples. Antioxidant activity was determined by the DPPH method revealed that all the tested extracts and fractions exhibited strong antioxidant activity especially the total ethanolic extract, chloroform and ethyl acetate fractions of the fruits.