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Announcement to National University students: The periodic exam will be held for the offered course, Medicinal Plants

The periodic exam for students of the National University, offered course, medicinal plants, will be held on Monday, March 25, 2024, in the laboratories of the third floor, Building (A), at eleven in the morning.

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إعلانات الطلاب

A novel mesna-based electrochemical sensor embellished with silver nanoparticles for ultrasensitive analysis of modafinil Human Plasma

Research Abstract

Modafinil (MOD) is a CNS stimulant used for the treatment of narcolepsy, shift work sleep disorder, excessive daytime sleepiness, and post-COVID 19 neurological symptoms. In the literature, there is no report of square wave voltammetric (SWV) methods being used for the determination of MOD. This study describes, for the first time, the construction and evaluation of the analytical performance of a novel sensor for ultrasensitive SWV detection of MOD. The sensor was constructed by integration of silver nanoparticles (AgNPs) on Mesna (MSN) layers over a pencil graphite electrode (PGE) surface. The interface and morphological characteristics of the fabricated AgNPs@MSN/PGE sensor were investigated via cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and scanning electron microscopy (SEM). This sensor was found to enhance the electro-oxidation of MOD. The combination of AgNPs@MSN/PGE with SWV enabled the determination of MOD in its bulk form and in pharmaceutical and biological matrices at the nanomolar scale (LOD = 28.59 nM) with excellent recoveries. This study represents the first report describing an electrochemical procedure for MOD detection in human plasma. The established SWV method was also validated, and the results were consistent with ICH criteria. Finally, the presented SWV procedure provides a facile, sensitive, rapid, and cost-effective approach compared to other existing methods.

Research Authors
A novel mesna-based electrochemical sensor embellished with silver nanoparticles for ultrasensitive analysis of modafinil Human Plasma
Research Date
Research Journal
Analytical Methods
Research Publisher
RSC
Research Vol
15 (42)
Research Year
2023

Important announcement

The produce of the Pharmacognosy Department’s farm will be sold on Sunday, March 24, 2024, from ten in the morning, at the sales outlet in the faculty:

Item                                   price

Peppermint               2,25 LE

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خبر عام

A duty of condolence

 

She mourns

The family of the Faculty of Pharmacy - Assiut University, its dear loss

 Professor Dr

Hassan Hassan Ahmed Farag

Emeritus Professor in the Department of Pharmaceutical Medicinal Chemistry

The faculty family mourns his gentle character, generous assets, abundant knowledge, and dedication to performing his work. May God bestow his mercy on the deceased, place him in spacious gardens, and grant his family and relatives patience and solace. The faculty family also extends its sincere condolences and deep sympathy to the family of the deceased, his students, and his lovers. We belong to God and to Him we shall return.

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خبر عام

Announcement for grievance for graduate students

The applications will be starts for postgraduate students

)PhD - Master - Doctor of Pharmacy - Diplomas)

Starting from March 20, 2024 until March 28, 2024

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إعلانات الدراسات العليا

Announcement to students of the PharmD Clinical Pharmacy Program (semester 6): The periodic and theoretical practical exam will be held for the course Pharmaceutical Medicinal Chemistry-2.

The periodic and theoretical practical exam for the course Pharmaceutical Medicinal Chemistry - 2 for clinical pharmacy students, semester (6),

 will be held on Thursday, March 21, 2024, at 10:30 a.m. in the department’s auditorium and laboratories.

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إعلانات الطلاب

Announcement for students of the fourth year of the Bachelor of Pharmacy program, the periodical and practical sheet examination will be held for the course Pharmaceutical Medicinal Chemistry-2.

the periodic and practical sheet exams for the Pharmaceutical Chemistry 2 course for third-year Pharm-D students

will be held on Thursday, March 21, 2024, from twelve to one-thirty in the afternoon in Hall (2).

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إعلانات الطلاب
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