To determine the potential toxic effects of aflatoxins (AFs), the ameliorative role of zinc oxide nanoparticles and activated charcoal against aflatoxicosis, and finally, the effective role of the recovery period against aflatoxins toxic effects and their residues. A total of 70 one-day-old Moulard ducklings were obtained and classified into seven groups, comprising 10 ducklings per group. The control group (G1) ducklings were fed on a basal diet free from AFs. Group 2 (G2) ducklings received a naturally AFs-contaminated feed with 50 ppb total AFs. Group 3 (G3) ducklings consumed 50 ppb AFs-contaminated feed and 10 mg/kg/feed zinc oxide nanoparticles (ZnONPs). Group 4 (G4) ducklings consumed 50 ppb AFs-contaminated feed and 1.5% of the ration activated charcoal. Group 5 (G5) ducklings consumed 50 ppb AFs-contaminated feed with ZnONPs and an activated charcoal combination. Group 6 (G6) ducklings …