Research Abstract
2-Methylimidazole (1) reacted with 3-dicyanomethylidine-1-ethyl-2-oxoindoline (2) in ethyl acetate to afford 5-amino-6-cyano-7,8-dihydro-1'-ethylspiro{imidazo[1,2-a]pyridine-7,3'-indolin}-2'-one (8), which used as a key intermediate for the synthesis of fused spiroheterocyclic derivatives of imidazo- pyridopyrimidine and/or imidazonaphthyridine nucleus incorporated indoline moiety. The chemical structures of all synthesized compounds were elucidated by the elemental and spectroscopic analyses.
Research Department
Research Journal
Heterocycles
Research Member
Research Pages
pp. 2791-2802
Research Rank
1
Research Vol
Vol. 75 No. 11
Research Year
2008