SUMMARY Aim: As a part of our continuing interest concerning the prevalence use of herbal medicine to treat common diseases in Al-Taif area, the present study aimed to assess the prevalence and indication of herbal medicine in digestive system complaints in Al-Taif area, Saudi Arabia. Methods: An anonymized self-administration questionnaire of 10 close-ended questions was filled in by 600 patients; only 300 of 600 patients (50%) completed the questionnaire. The sample was selected randomly considering the region of residency of respondents. Result: The present study revealed that 82.6% of the respondents used herbs for their digestive system problems. The following herbs: Anise, chamomile, pomegranate, peppermint, and ginger have been used commonly for digestive system complaints from the other. No side effects were recorded. Conclusion: The study concluded that a high proportion of the Al-Taif area population had been suffering from digestive system disorders. The majority of patients noticed improvement after the use of herbs to overcome the problems of the digestive system. Keywords: Herbal medicine, digestive system problems, questionnaire, Al-Taif population.