A novel disposable ultrasensitive sensor based on nanosized ceria uniformly loaded carbon nanofiber nanoceramic film wrapped on pencil graphite rods for electrocatalytic

Research Abstract

For the first time, we introduce a novel disposable and ultrasensitive sensing electrode made up of nanosized ceria uniformly loaded carbon nanofibers (CeNPs@CNF) sol-gel nanoceramic film (CF) wrapped on eco-friendly and inexpensive pencil graphite rods (PGRs) to explore their electro-catalytic detection of the anticancer drug capmatinib (CMB). The as-prepared CeNPs@CNF hybrid nanocomposite was described by XRD, SEM, TEM, HRTEM, and EDX analysis. The CV study clearly demonstrated that, the disposable CeNPs@CNF-CF/PGRE sensor exhibited excellent redox activities in the ideal probe [Fe(CN)6]3-/4-. Due to the outstanding electrochemical properties, larger electrochemically active surface area, and tremendous electro-catalytic activity of CeNPs@CNF, the reduction current of CMB on the CeNPs@CNF-CF/PGRE sensor is considerably higher than that of bare PGRE. The detection conditions …

Research Authors
Ahmed Z Alanazi, Khalid Alhazzani, Mohamed M El-Wekil, Al-Montaser Bellah H Ali, Mahmoud Darweesh, Hossieny Ibrahim
Research Date
Research Department
Department of Pharmaceutical Analytical Chemistry
Research Journal
Talanta
Research Member
Mohamed Mahmoud Abdel-Gaber El-Wekil
Almontaser bellah Hamed Ali
Research Vol
279
Research Year
2024

A novel urease-assisted ratiometric fluorescence sensing platform based on pH-modulated copper-quenched near-infrared carbon dots and methyl red-quenched red carbon dots for

Research Abstract

A novel and sensitive fluorescence ratiometric method is developed for urea detection based  on the pH-sensitive response of two fluorescent carbon dot (CD) systems: R-CDs/methyl red (MR) and NIR-CDs/Cu2+. The sensing mechanism involves breaking down urea using the enzyme urease, releasing ammonia and increasing pH. At higher pH, the fluorescence of NIR-CDs is quenched due to the enhanced interaction with Cu2+, while the fluorescence of R-CDs is restored as the acidic MR converts to its basic form, removing the inner filter effect. The ratiometric signal (F608/F750) of the R-CDs/MR and NIR-CDs/Cu2+ intensities changed in response to the pH induced by urea hydrolysis, enabling selective and sensitive urea detection. Detailed spectroscopic and morphological investigations confirmed the fluorescence probe design and elucidated the sensing mechanism. The method exhibited excellent …

Research Authors
Ahmed Z Alanazi, Khalid Alhazzani, Aya M Mostafa, James Barker, Hossieny Ibrahim, Mohamed M El-Wekil, Al-Montaser Bellah H Ali
Research Date
Research Department
Department of Pharmaceutical Analytical Chemistry
Research Journal
Microchimica Acta
Research Member
Mohamed Mahmoud Abdel-Gaber El-Wekil
Almontaser bellah Hamed Ali
Aya Mounier Mostafa Mohammad
Research Publisher
Springer Vienna
Research Year
2024

Self‐Calibrating Copper‐Based Metal Organic Frameworks for Ratiometric Electrochemical Sensing of Creatinine

Research Abstract

Nanostructures that can undergo redox reactions have significant potential for electrochemical analysis. They can act as signal amplifiers to determine concentrations of targets in biological samples. In this work, a rational combination of electroactive copper‐based metal‐organic frameworks (Cu‐MOFs) and ferrocene carboxylic acid (Fc) was designed for ratiometric electrochemical detection of creatinine. The synthesized Fc@Cu‐MOFs exhibited two redox signals from the Cu2+/Cu+ and Fe3+/Fe2+ systems in the skeleton of Cu‐MOFs and Fc, respectively. In the presence of chloride (Cl−), the oxidation current of Cu+ increased due to formation of solid‐state cuprous chloride (CuCl). Adding strong Cu+ chelators, e. g. creatinine, coordinated with Cu+ and caused the current output of solid‐state CuCl to decrease significantly. The anodic current of Fc did not appreciably change, serving as an internal reference signal. The ratiometric responses (ICu(I)/IFc) changed with increasing concentrations of creatinine from 0.017–130 μM with a detection limit (S/N=3) of 0.005 μM. The main advantages of Fc@Cu‐MOFs are the low LOD, high selectivity, and reliability, making it a suitable platform for determining creatinine in human serum and urine samples. The as‐fabricated sensor is a reliable approach for determining (bio) molecules that can form stable complexes with Cu+ ions.

Research Authors
Ahmed Z Alanazi, Khalid Alhazzani, Al‐Montaser Bellah H Ali, Mahmoud Darweesh, Hossieny Ibrahim, Mohamed M El‐Wekil
Research Date
Research Department
Department of Pharmaceutical Analytical Chemistry
Research Journal
Electroanalysis
Research Member
Mohamed Mahmoud Abdel-Gaber El-Wekil
Almontaser bellah Hamed Ali
Research Publisher
Wiley
Research Rank
International
Research Year
2024

Surface engineering of carbon microspheres with nanoceria wrapped on MWCNTs: a dual electrocatalyst for simultaneous monitoring of molnupiravir and paracetamol

Research Abstract

In the present study, nanoceria-decorated MWCNTs (CeNPs@MWCNTs) were synthesized using a simple and inexpensive process. Molnupiravir (MPV) has gained considerable attention in recent years due to the infection of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Since some people infected with COVID-19 experience fever and headaches, paracetamol (PCM) has been prescribed to relieve these symptoms. Therefore, there is an urgent need to monitor and detect these drugs simultaneously in pharmaceutical and biological samples. In this regard, we developed a novel sensor based on nanoceria-loaded MWCNTs (CeNPs@MWCNTs) for simultaneous monitoring of MPV and PCM. The incorporation of CeNPs@MWCNTs electrocatalyst into a glassy carbon microsphere fluorolube oil paste electrode (GCMFE) creates more active sites, which increase the surface area, electrocatalytic 

Research Authors
Yahya S Alqahtani, Ashraf M Mahmoud, Mohamed M El-Wekil, Hossieny Ibrahim
Research Date
Research Department
Department of Pharmaceutical Analytical Chemistry
Research Journal
RSC advances
Research Member
Mohamed Mahmoud Abdel-Gaber El-Wekil
Research Publisher
Royal Society of Chemistry
Research Rank
International
Research Vol
14
Research Year
2024

Important Announcement for All Pharmacy Students

All students in the different programs (Pharm D Program – Pharm D Clinical Pharmacy Program – Pharm-D National University Program) are kindly requested to register their courses promptly according to the announced deadlines.

This is in accordance with what is stated in the Faculty's internal regulations, Article (6): Registration - Clause (B), which includes:

"Students are not allowed to register after the specified times… etc."

news category
إعلانات الطلاب

The President of the University and his Vice President for Education and Student Affairs on an inspection tour of the Faculty of Pharmacy at the beginning of the second semester of the 2024/2025 academic year

Professor Dr. Ahmed El-Menshawy, President of the University, accompanied by Professor Dr. Ahmed Abdel-Mawla, Vice President of the University for Education and Student Affairs, conducted an inspection tour of the Faculty of Pharmacy at the beginning of the second semester of the 2024/2025 academic year. They were welcomed by Professor Dr. Gihan Nabil Fateh, Dean of the Faculty, Professor Dr. Hassan Rifaat Hassan, Vice Dean for Education and Student Affairs, Professor Dr. Mohamed Mahmoud Abdel-Latif, Vice Dean for Community Service and Environmental Development, and Mr. Tarek Said, Faculty Secretary. The President assured himself of the regularity of the educational process. During his speech to the students, he urged them to commit to all aspects of the educational process, including lectures, practical lessons, and activities. He also congratulated the students on the beginning of the second semester of the 2024/2025 academic year, wishing them a year full of success, distinction, creativity, and success.
The tour took place on Sunday, February 9, 2025

 

معالى رئيس الجامعة ونائبه لشئون التعليم والطلاب فى جولة تفقدية لكلية الصيدلة مع بداية الفصل الدراسى الثانى للعام الجامعى 2024/2025م

معالى رئيس الجامعة ونائبه لشئون التعليم والطلاب فى جولة تفقدية لكلية الصيدلة مع بداية الفصل الدراسى الثانى للعام الجامعى 2024/2025م

 

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خبر عام

Congratulations to Prof. Gihan Nabil Fateh, Dean of the Faculty, the Vice Deans, and the Heads of Departments on the occasion of the second semester of the 2024/2025 academic year

 

Professor Dr. Gihan Nabil Fateh, Dean of the Faculty, the Vice Deans, the Heads of Departments, and the Faculty Secretary extend their sincere congratulations to the faculty members, staff, and students on the occasion of the start of the second semester of the 2024/2025 academic year. They wish them a successful academic year, God willing

تهنئة السيده الأستاذ الدكتور / جيهان نبيل فتيح – عميد الكلية – والسادة الوكلاء ورؤساء الأقسام بمناسبة الفصل الدراسي الثانى للعام الجامعى 2024/2025

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خبر عام

The thesis defense of Mr. Master/ Gamal Salah eldin Tawfiq, who is enrolled for a Doctorate of Philosophy in Pharmaceutical Sciences (Industrial Pharmacy), will be discussed on Thursday, February 27, 2025

The thesis defense of Mr. Master/ Gamal Salah eldin Tawfiq, who is enrolled for a Doctorate of Philosophy in Pharmaceutical Sciences (Industrial Pharmacy), will be discussed on Thursday, February 27, 2025

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إعلانات الدراسات العليا

In the context of the collaboration between the Ministry of Higher Education and Scientific Research and the Ministry of Social Solidarity, the Supreme Council of Universities issued a decision approving the launch of the Moudah Digital Platform for dista

✴️للتسجيل في المبادرة ادخل علي اللينك الاتي⬇️⬇️

https://mawadda-eg.com

  • مرفق فيديو توضيحي لكيفيه التسجيل في المبادرة⬇️⬇️

فيديوتوضيحى لمنصة مودة والاجابة عن الأسئلة الشائعة

 

في إطار التعاون بين وزارة التعليم العالي والبحث العلمي ووزارة التضامن الاجتماعي تم صدور قرار المجلس الأعلى للجامعات بالموافقة على إطلاق منصة مودة الرقمية للتعليم عن بعد الخاصة بوزارة التضامن الاجتماعي

بمحتواها العلمي على المواقع الالكترونية بكليات الجامعات بشكل تجريبي للطلاب المقيدين بالجامعات

ويأتي الاطلاق بجامعة دمياط تحت إشراف الاستاذ الدكتور   رئيس الجامعة

 

ما هي منصة مودّة
✅مودّة مبادرة تسعى إلى وحدة الأسرة المصرية، والحد من نسب الطلاق التى ارتفعت بشكل ملحوظ خلال السنوات الأخيرة ، وتهدف مبادرة مودّة إلى تزويد المقبلين على الزواج، بالتأهيل النفسي والإجتماعي الكافي لتشكيل الأسرة وحل أي خلافات محتملة، وكذلك دعم مكاتب فض المنازعات الأسرية للقيام بدور في الحد من حالات الطلاق، بالإضافة إلى مراجعة التشريعات التي تدعم الأسرة وتحمي حقوق الزوجين والأطفال.

✅كما تقوم الدورة التدريبية بالتوعية بأهمية الفحوصات الطبية الواجب تطبيقها قبل وخلال الزواج، كما توعّي بأهم الحلول الصحية لتنظيم الأسرة. وتهتم "مودّة" خلال دورتها التدريبية بإلقاء الضوء على الرأي الشرعي في كثير من القضايا المتعلقة بالزواج، ومن بينها الأركان والشروط والحقوق والواجبات المتبادلة بين الزوجين.

  • الهدف من الدورة

● تهدف هذه الدورة التدريبية إلى تأهيل الشباب المصري المقبل على الزواج، من الجنسين، وإعدادهم لبدء حياة زوجية ناجح.

● التأهيل النفسي والاجتماعي والشرعي لطرفي العلاقة، لبناء شراكة تقوم على الحب والاحترام والمسؤولية

. ● التوعية بالشروط الواجب توافرها لبدء أولى خطوات الحياة الزوجية

. ● تثقيف الشباب المقبل على الزواج، من خلال عرض نماذج ناجحة في الحياة العملية والأسرية.

  • توصيف الدورة

تتعرف خلال هذه الدورة التدريبية على كافة الجوانب الاجتماعية الواجب مراعاتها لبناء علاقة زوجية وأسرية ناجحة، ابتداءً من معايير اختيار شريك الحياة، مروراً بأسس التواصل والتفاهم بين الزوجين والتعرف على الاحتياجات العاطفية لكلاً منهما، كما تصحح بعض المفاهيم والأفكار الاجتماعية المغلوطة المتعلقة بالزواج والإنجاب. تقوم الدورة التدريبية بالتوعية بأهمية الفحوصات الطبية الواجب تطبيقها قبل وخلال الزواج، كما توعّي بأهم الحلول الصحية لتنظيم الأسرة. وتهتم "مودّة" خلال دورتها التدريبية بإلقاء الضوء على الرأي الشرعي في كثير من القضايا المتعلقة بالزواج، ومن بينها الأركان والشروط والحقوق والواجبات المتبادلة بين الزوجين.

وفي نهاية الدورة التدريبية يحصل المتدرب على شهاده يتم ارسالها علي الايميل الخاص به بعد اجتيازه للكورس

news category
إعلانات الطلاب
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