Do you have any questions? (088) 2080369 - 2345622 Pharmacy_QAAU@pharm.aun.edu.eg
God willing, the meeting of the Pharmaceutics Department Board of the Faculty of Pharmacy No. (501) will be held onالMonday, June 6 2022 at 10:00 AM. in the teaching hall on the third floor under the chairmanship of the Faculty to discuss the topics that we will inform you later.
Under the patronage of Prof. Dr. Tarek El-Gamal - President of the University and Prof. Dr. Maha Ghanem - Vice-President for Community Service and Environmental Development, Prof. Dr. Ahmed Mohamed Abdel Mawla - Dean of the faculty and Prof. Dr. Mahmoud El Badry Abdel Muttalib - Vice Dean For Community Service Affairs and Environmental Development, member of the Technical Support Committee for the Best Environmentally Friendly Faculty Competition from the Environmental Studies Center at the university were welcomed. The committee consisted of Prof. Dr. Farouk Abdel Kawy - Professor at the Faculty of Agriculture and Adviser to the President of the University for Environmental Affairs - Prof. Dr. Thabet Abdel Moneim Ibrahim - Director of the Environmental Studies and Research Center at the university - Dr. Essam Adel Ahmed - Member of the Center - Faculty of Arts, where the visit program included examining the files of all the activities carried out by the Environmental Affairs Sector in the faculty in general, with an explanation from the Vice Dean for Community Service and Environmental Development. The members of the committee praised the efforts made by the sector during the academic year 2021/2022
Visited on Sunday 4/22/2022 AD
Novel pyrrolo [2,3-b] pyrrole derivatives were synthesized and their hypolipidemic activity was assessed in hyperlipidemic rats. The chemical structures of the new derivatives were confirmed through spectral analysis. Compounds 5 and 6 were revealed to be the most effective hypolipidemic agents, with considerable hypocholesterolemic and hypotriglyceridemic effects. They appear to be promising candidates for creating new powerful derivatives with anti-atherosclerotic and hypolipidemic properties. As for antimicrobial activity, some of the tested compounds showed moderate activity against Pseudomonas aeruginosa: compound 2 revealed an MIC value of 50 μg/mL, compared to 25 μg/mL for ciprofloxacin. Compound 3 showed good antimicrobial activity against Staphylococcus aureus, comparable to ciprofloxacin, and roughly half the activity of ampicillin, according to MIC values. Compound 2 has an MIC approximately 25% of that of clotrimazole against Candida albicans. Compound 2 also showed the highest antioxidant activity with 59% inhibition of radical scavenging activity. Additionally, the cytotoxic activity of these new derivatives 1–7 was investigated and most of them showed good anticancer activity against the three tested cell lines.
