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Iron-Mediated Cleavage of C-C Bonds in Vicinal Tricarbonyl Compounds in Water

Research Abstract
Three of a kind: Vicinal tricarbonyl compounds undergo C-C cleavage mediated by ferric ions (see scheme). The observed cleavage of ninhydrin and dehydroascorbic acid has relevance for amino acid detection and the metabolism of vitamin C.
Research Authors
Jasmin Mecinović, Refaat B. Hamed, Christopher J. Schofield
Research Department
Research Journal
Angew. Chem. Int. Ed., DOI: 10.1002/anie.200806296
Research Member
Research Rank
1
Research Vol
Vol. 48
Research Year
2009