Department Researches & Publications

Department of Pharmaceutical Organic Chemistry

Research

Our researches Plan:

1- Development, study in depth of pharmaceutical organic chemistry and illustration of its synthetic, mechanistic, and industrial applications.

2- Design and synthesis of different classes of compounds such as: Triazoles, benzimidazoles, piperazinedione and thiadiazine derivatives and others A special focus on xanthine and pyridazinone derivatives

3- Structural elucidation of the target compounds utilizing: IR,1H-NMR, MS in addition to elemental analysis Optical Rotation

4- Biological screening: Antimicrobial: antibacterial, antifungal and antituberculosis in addition to anthlemintic activity. Anti-inflammatory, analgesic, antipyretic activities and ulcerogenicity determination. Cardiotonic and hypotensive activities. Hypoglycemic activity. Anticonvulsant activity.

5- Other titles in consideration: Synthesis of new dendimers of potential biological activity. Applications of photochemical reactions for synthesis of certain organic compounds of potential biological activity. Synthesis of some antineurodegenerative compounds. Synthesis of certain nucleosides of potential biological activity. Synthesis of certain adenine derivatives of possible antiviral activity.

# Title Research Year
211 A Combined Experimental Green Flow-Injection Procedure and Computational Analysis to Determine Amino Acids 2013
212 Assessment of New Anti-HER2 Ligands Using Combined Docking, QM/MM Scoring and MD Simulation 2013
213 Design, Synthesis and Molecular Docking of Some New 1,2,4-Triazolobenzimidazol-3-yl Acetohydrazide Derivatives with Anti-Inflammatory-Analgesic Activities 2013
214 Design, Synthesis and Molecular Docking of Some New 1,2,4-Triazolobenzimidazol-3-yl Acetohydrazide Derivatives with Anti-Inflammatory-Analgesic Activities 2013
215 Design, Synthesis and Molecular Docking of Some New 1,2,4-Triazolobenzimidazol-3-yl Acetohydrazide Derivatives with Anti-Inflammatory-Analgesic Activities 2013
216 Design, Synthesis and Molecular Docking of Some New 1,2,4-Triazolobenzimidazol-3-yl Acetohydrazide Derivatives with Anti-Inflammatory-Analgesic Activities 2013
217 Phytochemical Screening and Antimicrobial Activity of EthOH/Water Ziziphus jujuba Seeds Extracts 2013
218 Steroid derivatives as inhibitors of steroid sulfatase 2013
219 Synthesis and antimicrobial evaluation of some new thiazoline and
thiazolidinone derivatives incorporating [1, 2, 4] triazolo [1, 5-a]
benzimidazole. 		2013
220 Synthesis and antimicrobial evaluation of some new thiazoline and
thiazolidinone derivatives incorporating [1, 2, 4] triazolo [1, 5-a]
benzimidazole. 		2013