Background: Urodynamic procedure identifies how well bladder, sphincters, and urethra are storing and releasing urine. Aim: Evaluate the importance of verbal and written instructions in outcomes of patients undergoing pressureflow urodynamic studies. Research Design: Randomized controlled trial. Patients and Methods: A total of 130 adult patients with no previous experience with urodynamics were attended to urodynamic outpatient clinic at Assiut Urology and Nephrology University Hospital to perform pressure-flow urodynamic studies from April 2016 to April 2018. Patients were divided randomly into 2 groups; odd numbers = study group (65 patients received routine instructions, detailed explanation about the procedure and received pressure-flow urodynamic brochure) and even numbers = control group (65 patients received routine instructions only). Tools: Assessment sheet for patients undergoing pressure-flow urodynamic studies, Spielberger six-item short form state trait anxiety inventory, urodynamic – patient satisfaction questionnaire and pressure-flow urodynamic brochure. Results: Study group was significantly better regarding all outcome parameters; cooperation, satisfaction, less procedure time and repetition, and less state trait anxiety inventory score. Conclusion: Patients education and good communication skills significantly affect outcomes of patients undergoing pressure-flow urodynamic studies.