The aim of this study was to assess the third year nursing student’s perception about an OSCE in Obstetrics and Gynecological Nursing. A descriptive design was utilized for collecting the data that are necessary to answer the research question. The sample consisted of 100 students who finished the 3rd year clinical teaching course of Obstetrics and Gynecological Nursing and were evaluated by an OSCE. The results of this study explored that more than one third of the students considered the announcement of the date and the place of examination were very good (39% and 38%, respectively). As regards the format of OSCE, the study identified that 41% of the students considered the revision done before examination was excellent. The majority of the students considered the quality of examination was excellent. Concerning the difficulties in time management during OSCE, more than half of the students (55%) were agreed. As regards the presence of emotional stress, more than two thirds of the students (77%) were agreed. In the light of the present study findings, it can be concluded that there is more need for careful preparation and organization of OSCE. The majority of the students appreciate the format of OSCE. The study has also highlighted that there are more need for training the students on time management and relieving their emotional stress during implementation of OSCE. It is essential to consider the recommended use of OSCE prescribed within wider context in nursing curriculum evaluation models. A larger study is needed to establish the effectiveness of OSCE within nursing education programs. An exploration of how successfully students transfer into clinical practice and to explore the validity and reliability of OSCE.