The first session of the scientific program "IBD EVOLUTION" on the development of diagnosis and treatment of immune colon and intestinal diseases

The first session of the scientific program "IBD EVOLUTION" on the development of diagnosis and treatment of immune colon and intestinal diseases

 

الجلسة الأولى للبرنامج العلمي "IBD EVOLUTION" حول التطور في تشخيص وعلاج أمراض القولون والأمعاء المناعية

تشهد قاعة المؤتمرات بالمستشفى الجامعي الرئيسي يوم الثلاثاء ٢٤سبتمر، في تمام التاسعة والنصف صباحا، بدء فعاليات الجلسة الأولى للبرنامج العلمي "IBD EVOLUTION" حول التطور في تشخيص وعلاج أمراض القولون والأمعاء المناعية،والذى تنظمه وحدة الجهاز الهضمي والكبد بقسم الأمراض الباطنة ورابطة الجهاز الهضمي والكبد بأسيوط بالتعاون مع جمعية صعيد مصر للجهاز الهضمي والكبد والمناظير .

تحت رعاية الأستاذ الدكتور أحمد المنشاوي رئيس الجامعة، والأستاذ الدكتور علاء عطية عميد كلية الطب ورئيس مجلس إدارة المستشفيات الجامعية، والأستاذ الدكتور محمد زين وكيل وزارة الصحة والسكان بأسيوط، والأستاذ الدكتور ضياء عبد الحميد نقيب الأطباء ومدير مستشفى جراحة المسالك بجامعة أسيوط، وتحت إشراف الأستاذ الدكتور محمد اليمني رئيس قسم الأمراض الباطنة، والأستاذ الدكتور حسين الأمين رئيس الجمعية والرابطة، والأستاذ الدكتور وائل عباس رئيس وحدة الجهاز الهضمي، والأستاذ الدكتور زين العابدين أحمد، والأستاذ الدكتور عصام الدين عبد المحسن رؤساء الندوة.

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The Faculty of Medicine family congratulates the faculty members whose names were included in the list of the most influential scientists in the world by Stanford University for the year 2021 AD for the total scientific production and research from the Fa

The Faculty of Medicine family congratulates the faculty members whose names were included in the list of the most influential scientists in the world by Stanford University for the year 2021 AD for the total scientific production and research from the Faculty of Medicine - Assiut University

The Faculty of Medicine family congratulates the faculty members whose names were included in the list of the most influential scientists in the world by Stanford University for the year 2021 AD for the total scientific production and research from the Faculty of Medicine - Assiut University

Basic Statistics Course for Postgraduate Students Organized by the Department of Obstetrics and Gynecology

Basic Statistics Course for Postgraduate Students Organized by the Department of Obstetrics and Gynecology

دورة الاحصاء الأساسية لطلاب الدرسات العليا والتي ينظمها قسم التوليد وامراض النساء

تحت رعاية

ا.د/ احمد المنشاوي- رئيس الجامعة

ا.د/ علاء عطية- عميد كلية الطب ورئيس مجلس إدارة المستشفيات الجامعية

ا.د/ محمود عبد العليم- نائب رئيس الجامعة لشئون خدمة المجتمع وتنمية البيئة.

ا.د/ أماني عمر- وكيل الكليه لشئون الدراسات العليا والبحوث

وتحت اشراف

ا.د احمد نصر - رئيس القسم ومدير مستشفى صحة المرأة

ا.د محمد فتح الله- مدير مركز تطوير التعليم الطبي

ا.د علاء اسماعيل- رئيس وحدة التدريب والتقييم WPBA

وذلك بقاعة المؤتمرات بمستشفى صحة المرأة.

تهنئة اسرة كلية الطب الدكتور/ ياسر فاروق عبدالرحيم لتعيينه مديراً لمستشفى الاطفال الجامعى

تهنئة اسرة كلية الطب الدكتور/ ياسر فاروق عبدالرحيم لتعيينه مديراً لمستشفى الاطفال الجامعى

تهنئة اسرة كلية الطب

الدكتور/ ياسر فاروق عبدالرحيم لتعيينه مديراً لمستشفى الاطفال الجامعى

Congratulations to the Faculty of Medicine family Professor Dr. / Mona Abdel Hamid El-Baz On the occasion of her appointment as Head of the Department of Medical Biochemistry

Congratulations to the Faculty of Medicine family Professor Dr. / Mona Abdel Hamid El-Baz On the occasion of her appointment as Head of the Department of Medical Biochemistry

Congratulations to the Faculty of Medicine family
Professor Dr. / Mona Abdel Hamid El-Baz
On the occasion of her appointment as Head of the Department of Medical Biochemistry

Congratulations to the Faculty of Medicine family Professor Dr. / Mona Abdel Hamid El-Baz On the occasion of her appointment as Head of the Department of Medical Biochemistry

Congratulations to the Faculty of Medicine family Professor Dr. / Mona Abdel Hamid El-Baz On the occasion of her appointment as Head of the Department of Medical Biochemistry

Congratulations to the Faculty of Medicine family
Professor Dr. / Mona Abdel Hamid El-Baz
On the occasion of her appointment as Head of the Department of Medical Biochemistry

Congratulations to the Faculty of Medicine family Prof. Dr. Hatem Galal Zaki for assuming the position of President-Elect of the International Society of Orthopaedic Surgery SICOT

Congratulations to the Faculty of Medicine family Prof. Dr. Hatem Galal Zaki for assuming the position of President-Elect of the International Society of Orthopaedic Surgery SICOT

Congratulations to the Faculty of Medicine family
Prof. Dr. Hatem Galal Zaki for assuming the position of President-Elect of the International Society of Orthopaedic Surgery SICOT

Invitation to discuss the doctoral thesis of Dr. Hadeer Mustafa Hassouna - Assistant Lecturer, Department of Clinical Pathology - Faculty of Medicine - Assiut University

Invitation to discuss the doctoral thesis of Dr. Hadeer Mustafa Hassouna - Assistant Lecturer, Department of Clinical Pathology - Faculty of Medicine - Assiut University

Invitation to discuss the doctoral thesis of Dr. Hadeer Mustafa Hassouna - Assistant Lecturer, Department of Clinical Pathology - Faculty of Medicine - Assiut University

Impact of porous microsponges in minimizing myotoxic side effects of simvastatin

Research Abstract

Simvastatin (SV) is a poorly soluble drug; its oral administration is associated with a significant problem: Myopathy. The present study aims to formulate SV microsponges that have the potential to minimize the myotoxicity accompanying the oral administration of the drug. SV microsponges were prepared by exploiting the emulsion solvent evaporation technique. The % entrapment efficiency (%EE) of the drug approached 82.54 ± 1.27%, the mean particle size of SV microsponges ranged from 53.80 ± 6.35 to 86.03 ± 4.79 µm in diameter, and the % cumulative drug release (%CDR) of SV from microsponges was significantly higher than that from free drug dispersion much more, the specific surface area of the optimized microsponges formulation was found to be 16.6 m2/g revealed the porosity of prepared microsponges. Histological and glycogen histochemical studies in the skeletal muscles of male albino rats revealed that microsponges were safer than free SV in minimizing myotoxicity. These findings were proven by Gene expression of Mitochondrial fusion and fission (Mfn1) & (Fis1) and (Peroxisome proliferator-activated receptor gamma co-activator 1α) PGC-1α. Finally, our study ascertained that SV microsponges significantly decreased the myotoxicity of SV.

Research Authors
Ahmed U. Ali, Mahmoud Abd-Elkareem, Amira A. Kamel, Nasser S. Abou Khalil, D. Hamad, Nasr Eldin Hussein Nasr, Maha A. Hassan & Tahani H. El Faham
Research Department
Department of Medical Physiology
Research Journal
scientific reports
Research Member
Nasser Sayed Abou Kalil Abdel Satr
Amira Abdel Hamid Kamel Mohammed
Research Year
2023
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