OBJECTIVE: The hand measurements were carried out on both hands and all fingers of each volunteer to perform a standard for the Aswan population and to correlate the hand length with the body height. MATERIAL AND METHODS: Hand print impressions of 1000 adult Aswanian volunteers (500 males and 500 females) were taken. They are right handed. All volunteers were from Aswan governate by both parents.Their ages were from 18-20 years old. They have good health and free of any chronic debilitating disease. The parameters studied were maximum length and breadth of both hands and for each finger of both hands. Hand Index (maximum hand width / hand length X 100) and finger Index (maximum finger width / finger length X 100) for each finger were estimated. For estimation of body height a Height Measuring Stand was used. The all measurements were done at fixed time from 9 am to 11 am to avoid the diurnal variation the data were analyzed statistically. RESULTS: The hand parameters in the male were found to be statistically significant longer and broader than the female. A symmetrical male and female hands were found. A significant correlation between the body height and all hand parameters were found, the greater correlation was found with the hand length. A generalized multiple regression equation has been designed to estimate stature from values of hand length and hand breadth in Aswanians regardless of sex or laterality in the form: S (stature) = 55.3 + 5.5 HL + 1.9 HB ± 5.1. This equation may be helpful to obtain approximate stature when there is difficulty in obtaining a direct measurement of the body height. CONCLUSION: Variations in hand measurements and body height may be attributed to several factors like genetic, racial, geographical, climatic and nutritional.

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Background: Lung cancer is one of the leading causes of mortality in the world. The main reason for poor lung cancer prognosis is that the patients are often diagnosed in late stages with advanced disease. The expression of some miRNAs has been reported to be involved in diagnosis, classification and prognosis of lung cancer. This study aimed to evaluate the role of plasma miRNA 155 and miRNA 197 in lung cancer. Subjects and methods: This study included sixty lung cancer patients and twenty apparently healthy individuals. Complete blood picture, kidney and liver function tests, serum glucose, lactate dehydrogenase, and carcinoembryonic antigen (CEA) were done by standard methods. Plasma miRNA 155 and miRNA 197 were done by Real-time polymerase chain reaction. Results: There were significant elevations in serum CEA and plasma miRNA155 and miRNA197 in lung cancer patients compared to control group. miRNA155 and miRNA197 showed significant elevation with advanced tumor stage and metastasis. CEA at cutoff (28 ng/ml) resulted in 74% sensitivity. MiRNA 155 at cutoff (152 fold changes) resulted in 93% sensitivity. MiRNA 197 at cutoff (159.18 fold changes) resulted in 90% sensitivity. The specificity was 100% for all. Combined use of miRNA155, miRNA197 and CEA increased the sensitivity to 94.8%. Conclusion: Plasma miRNA 155 and miRNA197 are more sensitive than CEA as tumor markers for lung cancer. They are correlated with tumor stage and presence of metastasis but not correlated with histological types.

Background: Lung cancer is one of the leading causes of mortality in the world. The main reason for poor lung cancer prognosis is that the patients are often diagnosed in late stages with advanced disease. The expression of some miRNAs has been reported to be involved in diagnosis, classification and prognosis of lung cancer. This study aimed to evaluate the role of plasma miRNA 155 and miRNA 197 in lung cancer. Subjects and methods: This study included sixty lung cancer patients and twenty apparently healthy individuals. Complete blood picture, kidney and liver function tests, serum glucose, lactate dehydrogenase, and carcinoembryonic antigen (CEA) were done by standard methods. Plasma miRNA 155 and miRNA 197 were done by Real-time polymerase chain reaction. Results: There were significant elevations in serum CEA and plasma miRNA155 and miRNA197 in lung cancer patients compared to control group. miRNA155 and miRNA197 showed significant elevation with advanced tumor stage and metastasis. CEA at cutoff (28 ng/ml) resulted in 74% sensitivity. MiRNA 155 at cutoff (152 fold changes) resulted in 93% sensitivity. MiRNA 197 at cutoff (159.18 fold changes) resulted in 90% sensitivity. The specificity was 100% for all. Combined use of miRNA155, miRNA197 and CEA increased the sensitivity to 94.8%. Conclusion: Plasma miRNA 155 and miRNA197 are more sensitive than CEA as tumor markers for lung cancer. They are correlated with tumor stage and presence of metastasis but not correlated with histological types.

Background: Lung cancer is one of the leading causes of mortality in the world. The main reason for poor lung cancer prognosis is that the patients are often diagnosed in late stages with advanced disease. The expression of some miRNAs has been reported to be involved in diagnosis, classification and prognosis of lung cancer. This study aimed to evaluate the role of plasma miRNA 155 and miRNA 197 in lung cancer. Subjects and methods: This study included sixty lung cancer patients and twenty apparently healthy individuals. Complete blood picture, kidney and liver function tests, serum glucose, lactate dehydrogenase, and carcinoembryonic antigen (CEA) were done by standard methods. Plasma miRNA 155 and miRNA 197 were done by Real-time polymerase chain reaction. Results: There were significant elevations in serum CEA and plasma miRNA155 and miRNA197 in lung cancer patients compared to control group. miRNA155 and miRNA197 showed significant elevation with advanced tumor stage and metastasis. CEA at cutoff (28 ng/ml) resulted in 74% sensitivity. MiRNA 155 at cutoff (152 fold changes) resulted in 93% sensitivity. MiRNA 197 at cutoff (159.18 fold changes) resulted in 90% sensitivity. The specificity was 100% for all. Combined use of miRNA155, miRNA197 and CEA increased the sensitivity to 94.8%. Conclusion: Plasma miRNA 155 and miRNA197 are more sensitive than CEA as tumor markers for lung cancer. They are correlated with tumor stage and presence of metastasis but not correlated with histological types.

Background: Lung cancer is one of the leading causes of mortality in the world. The main reason for poor lung cancer prognosis is that the patients are often diagnosed in late stages with advanced disease. The expression of some miRNAs has been reported to be involved in diagnosis, classification and prognosis of lung cancer. This study aimed to evaluate the role of plasma miRNA 155 and miRNA 197 in lung cancer. Subjects and methods: This study included sixty lung cancer patients and twenty apparently healthy individuals. Complete blood picture, kidney and liver function tests, serum glucose, lactate dehydrogenase, and carcinoembryonic antigen (CEA) were done by standard methods. Plasma miRNA 155 and miRNA 197 were done by Real-time polymerase chain reaction. Results: There were significant elevations in serum CEA and plasma miRNA155 and miRNA197 in lung cancer patients compared to control group. miRNA155 and miRNA197 showed significant elevation with advanced tumor stage and metastasis. CEA at cutoff (28 ng/ml) resulted in 74% sensitivity. MiRNA 155 at cutoff (152 fold changes) resulted in 93% sensitivity. MiRNA 197 at cutoff (159.18 fold changes) resulted in 90% sensitivity. The specificity was 100% for all. Combined use of miRNA155, miRNA197 and CEA increased the sensitivity to 94.8%. Conclusion: Plasma miRNA 155 and miRNA197 are more sensitive than CEA as tumor markers for lung cancer. They are correlated with tumor stage and presence of metastasis but not correlated with histological types.

Background: Lung cancer is one of the leading causes of mortality in the world. The main reason for poor lung cancer prognosis is that the patients are often diagnosed in late stages with advanced disease. The expression of some miRNAs has been reported to be involved in diagnosis, classification and prognosis of lung cancer. This study aimed to evaluate the role of plasma miRNA 155 and miRNA 197 in lung cancer. Subjects and methods: This study included sixty lung cancer patients and twenty apparently healthy individuals. Complete blood picture, kidney and liver function tests, serum glucose, lactate dehydrogenase, and carcinoembryonic antigen (CEA) were done by standard methods. Plasma miRNA 155 and miRNA 197 were done by Real-time polymerase chain reaction. Results: There were significant elevations in serum CEA and plasma miRNA155 and miRNA197 in lung cancer patients compared to control group. miRNA155 and miRNA197 showed significant elevation with advanced tumor stage and metastasis. CEA at cutoff (28 ng/ml) resulted in 74% sensitivity. MiRNA 155 at cutoff (152 fold changes) resulted in 93% sensitivity. MiRNA 197 at cutoff (159.18 fold changes) resulted in 90% sensitivity. The specificity was 100% for all. Combined use of miRNA155, miRNA197 and CEA increased the sensitivity to 94.8%. Conclusion: Plasma miRNA 155 and miRNA197 are more sensitive than CEA as tumor markers for lung cancer. They are correlated with tumor stage and presence of metastasis but not correlated with histological types.

Aim: To present a very rare case of bilaterally-complicated horseshoe kidney by nephrolithiasis in a patient with situsinversus with levocardia and skeletal anomalies. Case Report: A 41-year-old female presented by right loin pain. Abdominal ultrasound showed bilateral kidney stones with malrotation, right mild hydronephrosis and transposition of the abdominal organs. Chest X-ray showed the heart normal in the left side. Also, computed tomography revealed a horseshoe kidney with bilateral stones. After counseling the patient about the stones treatment options, she preferred extracorporeal shock-wave lithotripsy which was tried on the right side firstly, but it failed. So, percutaneous nephrolithotripsy was scheduled. Discussion: Situs inversus is a spectrum of congenital anomalies. Situsinversus totalis is the commonest variety and was reported with renal congenital anomalies like horseshoe kidney, acquired renal diseases like renal cell carcinoma, and in living kidney donation. However, situs inversus with levocardia is a rare variety with a known association to the congenital heart defects. Its association to a complicated horseshoe kidney and scoliosis could not be found in the English literature before the current case. Moreover, absence of congenital heart defects is extremely rare. Conclusion: Association of situs inversus with levocardia to skeletal anomalies and complicated horseshoe kidney is a unique situation. It indicates meticulous evaluation and management.

Aim: Presentation of an abdominoscrotal hydrocele case with a very rare association to multiple anomalies and separate abdominal and inguinoscrotal sacs. Case Report: A 21-year-old male patient presented with left-sided abdominoscrotal hydrocele, impalpable right testis, hydrocephalus and cerebral and musculoskeletal deformities. On abdominal ultrasonography, the abdominal and inguinoscrotal components were seen separated by a septum that was confirmed on surgery. Extended inguinal incision was used for repair and the post-operative course was uneventful. Discussion: Abdominoscrotal hydrocele is a rare entity and its simultaneous association to multiple anomalies, like in the current case, is a rarer finding. Non-intercommunication state is another very rare criteria of abdominoscrotal hydrocele which was clinically, sonographically and surgically demonstrated in this case. Extended inguinal incision was indicated and enough to deal with both abdominal and scrotal components. Conclusion: Abdominoscrotal hydrocele is mostly intercommunicating, but it is exceptionally non-intercommunicating and associated to multiple anomalies. Surgical excision via an extended inguinal incision may be indicated for voluminous cases and those with a solitary testis.

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