The Student Computer Unit announces the holding of a training course entitled: - Word 2007 Basics for Administrators and Staff at the Faculty

The Student Computer Unit announces the holding of a training course entitled (Word 2007 Basics for Administrators and Staff at the Faculty on Sunday and Monday, 15 - 16/12/2024. All candidates must attend at exactly ten o'clock in the morning in the unit's laboratories.

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Spectral, XRD, morphological, DFT, and molecular modeling investigations of newly prepared isatin Schiff base complexes

Research Authors
Bassant S. Moustafa, Mohamed M. Omar, Wesam S. Qayed, Hanan F. AbdEl-Halim, Gehad G. Mohamed
Research Department
Department of Medicinal Chemistry
Research Journal
Applied Organometallic Chemistry
Research Member
Wesam Saber Abdel-Aal Qayed
Research Vol
38
Research Year
2024

Meeting of the Libraries Committee of the College of Pharmacy and that will be on Monday, January 13, 2025

God willing, the meeting of the Libraries Committee at the College of Pharmacy and that will be on Monday, January 13, 2025, at ten in the morning at the invitation of Professor Mrs. Professor Dr. Gihan Nabil Hassan Fetih

This meeting will be held in the office of Mrs. Prof. Dr. / Dean of the College - Fifth Floor (Administrative Building).

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اجتماع اللجنة التنفيذية (لبرنامج Meeting of the Executive Committee (Clinical Pharmacy Program) and that will be on Monday, January 13, 2025. الاكلينيكية) وذلك يوم الأثنين 13 يناير 2025

 God willing, the Executive Committee meeting and that will be on Monday, January 13, 2025, at 10:30 AM.

The meeting will take place in the Faculty Council Hall, 5th Floor (Administrative Building)

Acting Dean of the Faculty

(Prof. Gihan Nabil Hassan Fetih)

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Disposable and sensitive electrochemical magneto-immunosensor for point-of-care HCV diagnostics: Targeting HCVcAg, the active viremia biomarker, in patient samples

Research Abstract
Early detection of hepatitis C virus (HCV) infection is crucial for eliminating this silent killer, especially in resource-limited settings. HCV core antigen (HCVcAg) represents a promising alternative to the current “gold standard” HCV RNA assays as an active viremia biomarker. Herein, a highly sensitive electrochemical magneto-immunosensor for the HCVcAg was developed. The biosensing strategy involved capturing HCVcAg using antibody-coated magnetic beads, followed by a sandwich immunoassay before electrochemical detection on disposable screen-printed electrodes. To achieve signal amplification and consequent enhanced sensitivity, the antigen-antibody reaction was detected with a biotinylated polyclonal antibody subsequently labelled with a streptavidin poly horseradish peroxidase conjugate followed by amperometric detection via a hydroquinone/hydrogen peroxide system. The developed biosensor exhibited a cathodic current variation directly proportional to the HCVcAg concentration over a wide range (0.1–500 ng/mL), with a detection limit of 10 pg/mL. Moreover, it successfully discriminated healthy control human plasma samples from HCVcAg-spiked samples, showed no interference from endogenous plasma constituents or cross-reactivity with other viruses tested, and possessed excellent percentage recoveries of HCVcAg (≥92.83%), demonstrating high specificity. The proposed bioplatform remained stable for at least ten days and showed excellent clinical performance in detecting HCVcAg across a cohort of thirty-six plasma and serum samples from active hepatitis C cases, and healthy individuals, with results matching those previously obtained using clinically validated qPCR and serological testing. In summary, this biosensor provides a simple, rapid and economic alternative to other available techniques such as ELISA and qPCR for early diagnosis of HCV infection.
 
Research Authors
Mohammad Nabil Abo-Zeid, Cheryl Walter, Katie Kitchman, Kirstine Eastick, Lynsey Corless, John Greenman
Research Department
Department of Pharmaceutical Analytical Chemistry
Research Journal
Biosensors and Bioelectronics
Research Member
Mohammad Nabil Abo-Zeid Ibrahim
Research Publisher
Elsevier
Research Vol
272
Research Website
https://doi.org/10.1016/j.bios.2024.117104
Research Year
2025

A meeting of the cultural and international relations committee, Faculty of Pharmacy and that will be on Sunday, January 12, 2025

The cultural and international relations committee will hold its monthly meeting and that will be on Sunday, January 12, 2025, at 10:00 AM

in the office of Vice Dean for Graduate Studies and Research Affairs.

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Meeting of the (Postgraduate Studies and Research) Committee at the Faculty of Pharmacy and that will be on Sunday, January 12, 2025

    God willing, the meeting of the Graduate Studies and Research Committee and that will be on Sunday, January 12, 2025 at 11:00 in the morning

And that in the office of the Prof. Dr. / Vice Dean for Graduate Studies and Research Affairs.

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Meeting of the committee for community and environmental development at the Faculty of Pharmacy That will be on Thursday, January 9, 2025

God willing, a meeting of the committee for community and environmental development will hold That will be on Thursday, January 9, 2025, at 10:00 AM

In the office of Vice Dean for Community Services and Environmental Development Affairs.

 

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