By the will of Allah, the scientific conference of the Pharmacology at the Faculty of Pharmacy will be held on Tuesday, April 29, 2025, at 11:00 AM. The conference will take place in the Department Council, 5th floor, Building (A).
Do you have any questions? (088) 2080369 - 2345622 Pharmacy_QAAU@pharm.aun.edu.eg
The Scientific Conference of the Pharmacology Department, Faculty of Pharmacy on Tuesday, April 29, 2025.
Pharmacy Assiut Research Ethics Committee (PH-AUREC) titled "Ethics in Scientific Research"
The Technology Services Unit at the Faculty of Pharmacy – Assiut University announces a workshop for students of the (First, Second, and Third) years of the National University, titled:-Preparing Students for E-Exams
Impact of oil type on the development and oral bioavailability of self-nanoemulsifying drug delivery systems containing simvastatin
Research Abstract
The aim of this work is to develop and evaluate self‑nanoemulsifying drug delivery systems (SNEDDS) containing simvastatin to increase its oral bioavailability. Formulation EO 5 (Ethyl oleate 9.3% w/w: Tween 80 49.4% w/w: Propylene glycol 39.3% w/w) and Formulation CL 14 (Clove oil 54.3% w/w: Tween 80 34.4% w/w: Transcutol‑P 9.3% w/w) were thoroughly studied. They showed emulsification time less than 1 min, droplet size in the nanometric range, and almost a complete drug release after 2 h. The in‑vitro dissolution profile of both formulations was found to be significant in comparison to the pure drug in pH 1.2 and 7.4 buffers (P < 0.0001). Furthermore, they demonstrated superior anti‑hyperlipidemic activity in comparison to simvastatin suspension (10 mg/kg/day). In order to investigate the impact of oil type on oral bioavailability, the selected formulations have been examined in terms of the in‑vivo pharmacokinetic study, and formulation EO 5 was found to have higher bioavailability. After oral administration of a single dose (40 mg/kg) of simvastatin‑loaded SNEDDS (CL14 and EO 5), a 1.5‑fold and 1.95‑fold increase in bioavailability were observed, respectively, as compared to simvastatin suspension. Hence, the results indicated that the developed SNEDDS could enhance the therapeutic efficacy and oral bioavailability of simvastatin.
Research Date
Research Department
Research File
s41598-024-71980-5 (2).pdf
(1.92 MB)
Research Journal
Scientific reports
Research Member
Research Publisher
Springer nature
Research Rank
Q2
Research Vol
14:22584
Research Website
https://www.nature.com/srep/
Research Year
2024
Announcement for Clinical Pharmacy Students – Class (10)The practical exam for the course "Drug Design"
The practical exam for Clinical Pharmacy students – Class (10)
for the course "Drug Design" will be held in the computer labs for Group (A) on Wednesday, April 30th, 2025.
news category
إعلانات الطلاب
Announcement for fifth-year Pharm D students: Practical exam for the optional course (Computer-aided Drug Design) will be held.
The practical exam for the elective course
"Computer-Aided Drug Design" for 5th-Year Pharm D students will be held in the computer labs
for Group (A) and Group (B) as follows:
|
Day |
Date |
Group |
Time |
|
Monday |
28/04/2025 |
Group (A) |
12:00 PM |
|
Tuesday |
29/04/2025 |
Group (B) |
12:00 PM |
All students must attend according to their assigned group and time.
No makeup exam will be given without an officially approved excuse.
news category
إعلانات الطلاب
Announcement for First-Year Pharm D and Clinical Pharmacy Students: The second-term mid-term exam and the theoretical and practical exam for the course "Pharmaceutical Organic Chemistry-2" will be held on Saturday, April 26, 2025.
The department announces that the second mid-term exam and the practical theory exam will be held on Saturday, April 26th, from 11:30 AM to 12:30 PM.
Please make sure to attend on time, as the exam will not be repeated.
Venue: Hall 2, beneath Lecture Hall B
Course Content for the mid-term Exam (10 Marks):
- Prof. Dr. Samia Galal Ahmed's section: “Aldehydes and Ketones” – Lectures 1 and 2
- Prof. Dr. Ola Ibrahim Abdel Razek's section: “Aliphatic and Aromatic Amines” – Lectures 1 and 2
Course Content for the Practical Theory Exam (15 Marks):
- All practical sessions
news category
قسم الكيمياء العضوية
Announcement for First-Year, Clinical Pharmacy, and National University Students: The second-term mid-term exam and the theoretical and practical exam for the course "Pharmaceutical Organic Chemistry-1" will be held on Sunday, May 4, 2025.
The department announces that the second mid-term exam and the second practical theory exam for the course Pharmaceutical Organic Chemistry - 1 (offered course) will be held on Sunday, May 4th, 2025, from 11:30 AM to 12:30 PM.
Please make sure to attend on time, as the exam will not be repeated.
Exam Venues:
- Pharm D : Hall 1
- Pharm D National University: Hall 2
- Pharm D Clinical: Department Lecture Hall
news category
قسم الكيمياء العضوية
Announcement for National University First-Year Students: The practical exam for the course Pharmacognosy-1 will be held on Saturday, April 26, 2025.
The department announces that the second mid-term exam and the second practical theory exam for the course Pharmaceutical Organic Chemistry - 1 (offered course) will be held on Sunday, May 4th, 2025, from 11:30 AM to 12:30 PM.
Please make sure to attend on time, as the exam will not be repeated.
Exam Venues:
- Pharm D : Hall 1
- Pharm D National University: Hall 2
- Pharm D Clinical: Department Lecture Hall
news category
خبر عام