Department Researches & Publications

Department of Medicinal Chemistry

Researches Our research spans a wide range from basic organic synthesis, drug design and development, structure elucidation of newly synthesized compound and natural products. The research focuses on the following strategic Research Themes: Design and synthesis of new chemical entities. Computer aided drug design studies. Structure-Activity relationship studies. Combinatorial chemistry. Prod rugs developments. Analytical methods for bioavailability and metabolic studies. Research within these Themes is carried out in multidisciplinary groupings focused on the discovery of novel techniques and/or enhancement of the already existing ones. At the department of Medicinal Pharmacy, We have major national and international collaborative research projects and a significant output of research publications in high-ranking journals. Our academic collaborators include many Universities in USA, Canada, Japan, and a number of major European universities.

# Title Research Year
31 Novel Azine Linked Hybrids of 2-indolinone and Thiazolodinone Scaffolds as CDK2 Inhibitors with Potential Anticancer Activity: In Silico Design, Synthesis, Biological, Molecular Dynamics and Binding Free Energy Studies 2022
32 Novel Spiro Hybrids of 2-indolinone and Thiazolodinone Scaffolds as Cell Cycle Checkpoints’ Pathways Regulators with potential anticancer activity 2022
33 Phytochemical investigation, molecular docking studies and DFT calculations on the antidiabetic and cytotoxic activities of Gmelina philippensis CHAM. 2022
34 Structure Based Design of Novel Azine Linked Hybrids of 2-Indolinone- Thiazolodine Scaffold as Potential Quorum Sensing Inhibitors for Fighting Antimicrobial Resistance 2022
35 Synthesis, computational study and biological evaluation of 9-acridinyl and 1-coumarinyl-1, 2, 3-triazole-4-yl derivatives as topoisomerase II inhibitors 2022
36 Crystal structure and quantum chemical calculations of (E)1-benzyl-3-((4-methoxyphenyl)imino)-5-methylindolin-2-one 2021
37 Inversion Kinetics of Some E/Z 3-(Benzylidene)-2-Oxo-indoline Derivatives and Their In Silico CDK2 Docking Studies 2021
38 Inversion Kinetics of Some E/Z 3-(Benzylidene)-2-Oxo-indoline Derivatives and Their In Silico CDK2 Docking Studies 2021
39 Inversion Kinetics of Some E/Z 3-(Benzylidene)-2-Oxo-indoline Derivatives and Their In Silico CDK2 Docking Studies 2021
40 Inversion Kinetics of Some E/Z 3-(Benzylidene)-2-Oxo-indoline Derivatives and Their In Silico CDK2 Docking Studies 2021