Objective: Determine the effect of CH on growth and ‎ development of children aged 1–60 months compared to normal children. Methodology: A cross sectional study with comparison group comprising 118 children with ‎CH and 236 normal children was conducted ‎in Assiut, Egypt. Growth was measured by weight and length/height.‎ Developmental delay was screened using the ASQ3.‎ Results: Mean age in both groups was 19.6 months. Mean weight of CH cases was 6991.3±1907.4 gm versus 6912.3±188.2 gm for normal children in children aged 1- Regarding thyroid function, 15% and 23% of CH cases revealed overt and subclinical hypothyroidism respectively. Overt hypothyroidism showed significantly higher developmental delays than either eu-thyroid or subclinical cases in the communication gross motor, fine motor, and personal–social domains (64.7%, 42.9%, 43.8% and 42,9% respectively) Conclusion: CH children were significantly overweight, stunted and developmentally delayed compared to normal children. Impaired thyroid function was not associated with growth defects but overt hypothyroid cases showed significant developmental delay. IQ testing and continuous monitoring are essential for all children with CH. Efficiently organized recording systems, treatment documents, and compliance and follow-up assessment results can facilitate hassle-free health-card retrieval

To identify proportion and etiology of respiratory distress (RD), its mortalities andassociated risk factors among neonates admitted to Neonatal Intensive Care Unit (NICU) ofAssiut University Children Hospital.

Methods

A cross-sectional study design was carriedout. All RD neonates admitted to NICU of Assiut University Children Hospital during thestudy period were included.

Results

Respiratory distress neonates constituted 52.9% of totaladmission. Hyaline membrane disease represented 45.8% of RD cases. The majority ofhyaline membrane disease cases (RDS) were preterm and low birth weight (96.2% & 93.7%% respectively). The majority of hyaline membrane diseased neonates who were treated bysurfactant or Continuous Positive Airway Pressure (CPAP) recovered (75.8%& 66.7%respectively) with significant statistically difference. The most fatal of respiratory distressdiseases were persistent pulmonary hypertension (91.2%). Significant independent factorsassociated with neonatal mortalities due to respiratory distress were residence, causes of RD,birth weight and place of delivery.

Conclusion

Hyaline membrane disease, pneumonia,transient tachypnea of the newborn (TTN), meconium aspiration syndrome (MAS) wereimportant causes of neonatal respiratory distress. Residence, causes of RD, birth weight andplace of delivery were significantly associated with respiratory distress mortalities.

Recommendation

Development of strategies aiming to reduction of RD among neonates ishighly recommended. Moreover, surveillance programs for neonatal mortality should becoupled with preventive measures and interventions for