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Assessment of Vitamin D Level in Preschool Children who Stutter

Research Abstract

Background: Stuttering, affecting approximately 5% of children, disrupts speech flow and poses challenges to psychosocial development. Its complex origins involve genetic, neurological, environmental, and psychological factors. This study aims to explore the potential link between stuttering in preschoolers and Vitamin D(VD) deficiency, a relatively unexplored area.

Objectives:  To study the association between stuttering in preschool-aged children and insufficient VD levels (specifically, 25-hydroxy cholecalciferol) in order to assign vitamin D deficiency as contributing factor for stuttering occurrence.

 Patients and Methods: A case-control study was conducted on 36 preschool Arabic-speaking children aged 4-6 years, employing a 2:1 design with 24 stutterers and 12 age- and sex-matched healthy controls. Stuttering severity was assessed using The Arabic Stuttering Severity Index, and serum vitamin D levels were evaluated using 25-hydroxy cholecalciferol.

Results:  Results indicated a higher prevalence of vitamin D deficiency in children who stutter compared to controls, though no statistically significant difference was found in the distribution of vitamin D classifications between the two groups. Additionally, there was a non-significant association between Arabic Stuttering Severity Index categories and vitamin D categories among children who stutter. Severe stuttering cases exhibited higher rates of vitamin D deficiency compared to insufficient levels, and a statistically significant negative correlation was observed between vitamin D levels and Arabic Stuttering Severity Index score values.

 Conclusion:  Stuttering is a common health concern, particularly among preschool-aged children. Lower vitamin D levels were observed in children who stuttered compared to controls, suggesting a potential link. Initial findings hint at an inverse relationship between vitamin D levels and stuttering severity. These results underscore the importance of further research to elucidate the role of vitamin D in stuttering.

 

 

Research Authors
Hazem Alawadli¹, Omar El Henawy², Hanan A. Mohamed3, Abdallah M. AbdElzaher3, Shaimaa Mostafa4
Research Date
Research Journal
Egyptian Journal of Ear, Nose, Throat and Allied Science
Research Pages
1-8
Research Rank
q4
Research Vol
25
Research Year
2024

Speech Sound Disorders in Arabic School aged Children with Adenoid Hypertrophy

Research Abstract

Background: Adenoid hypertrophy alters the posture of the oro-facial structures by obstructing the upper airways and restricting nasal breathing. These postural changes may eventually have an impact on facial skeletal development and dental occlusion. The postural adjustments may negatively impact a child’s life by affecting a number of speech-production factors.

 

Objective: This study aimed to detect the speech sound disorders in school aged Egyptian children with adenoid hypertrophy and if they were related to structure changes in the airway that caused by adenoid hypertrophy.

Methods: 300 school-aged Egyptian children aged from (5–15) years old with speech sound disorders (SSD). They were divided into 2 groups; Group 1 consisted of 150 children with speech (SSD) and adenoid hypertrophy, and Group 2 consisted of 150 children complained from (SSD) without adenoid hypertrophy. All children were evaluated by protocol of language assessment and articulation test used in Assiut University Hospital.

Results: Speech sound disorders (SSD) mainly the omission and distortion are more frequent in (group 2) while, the sub­stitution errors are more prominent in (group 1). The interdental sigmatism was the most frequent speech sound disorder in (group 1) especially those with adenoid hypertrophy occupying more than 50% of the airway, whereas, devoicing, gliding and back to front are more frequent in (group 2).

Conclusions: Adenoid hypertrophy can affects only the /s/ sound production which needs precise placements of the articula­tors especially the tongue, and seems to be vulnerable due to the structural alteration of the oral cavity caused by adenoid hypertrophy.

 

Research Authors
Hanan A. Mohamed1• Reham A. Ibrahem1
Research Date
Research Journal
Indian Journal of Otolaryngology and Head & Neck Surgery
Research Rank
q3
Research Year
2024

Impact of chronic rhinosinusitis on the laryngeal mucosa and voice quality in children aged from 6 to 18 years old

Research Abstract

Background: Persistent inflammation of the nose and sinuses for more than 3 months is known as chronic rhinosinusitis (CRS). Relation between CRS and voice problems had been considered, however studies that highlighted the existence of dysphonia in CRS patients or the effect of sinusitis on the individual voice and the larynx are sparse.

Objective: We aimed to detect the impacts of CRS on the laryngeal mucosa and voice quality among children (6-18 years old).

Methods: A total of 120 children aged (6-18) years old. They were divided into 2 groups: the controls (60 children) who are healthy, normal, and hadn't CRS, and the patient group (60 children) who met the CRS criteria. All children were evaluated by using the protocol of voice evaluation in Phoniatric Unit in Assiut university Hospital including auditory perceptual assessment of voice, flexible fiberoptic laryngoscope for visual assessment of the vocal tract and multidimensional voice profile for acoustic analysis.

Results: The most frequent presentations in CRS patient were chronic nasal obstruction and phonasthenic manifestations. There were statistically significant variations between both groups regarding auditory perceptual assessment, laryngeal findings and acoustic parameters. Additionally, there was a positive correlation between CRS severity and increasing grade of dysphonia.

Conclusions: CRS has impacts on auditory perception assessment of voice, laryngeal findings and some acoustic parameters such as fundamental frequency, soft phonation index and harmonic to noise ratio. Increasing severity of CRS correlated with progression of dysphonia. CRS is considered a risk element for development of dysphonia.

 

Research Authors
Eman Sayed Hassan 1, Ahmed Antar Saleh M. Badran 2, Sahar Sabri Abdel-Raheem3, Hanan A. Mohamed 1
Research Date
Research Journal
Egyptian Journal of Neck Surgery and Otolaryngology
Research Pages
34-45
Research Rank
local journal
Research Vol
10
Research Year
2024

Cognitive functions in Arabic speaking children with velopharyngeal insufficiency and their impact on speech intelligibility

Research Abstract

Background: Patients with orofacial cleft are at high risk for neurobehavioral problems including learning disability, impaired language function, psychosocial adjustment issues, and persistently reduced academic achievement. All these factors may be related to decrease intellectual abilities of those patients. The presence of velopharyngeal insufficiency (VPI) leads to affection of speech intelligibility due to atypical consonant productions, abnormal nasal resonance, nasal air emission, compensatory articulatory mechanism, and facial grimace.

Objective: This study aimed at assessing the cognitive functions of patients with (VPI) and their effect on speech intelligibility.

Methods: Fifty patients with (VPI) were selected from the Outpatient Clinic of the Phoniatric Unit in Assiut University Hospital. All patients were evaluated by protocol of nasality assessment including auditory perceptual assessment of speech, assessment of overall intelligibility of speech, nasoendoscopy, and psychometric evaluation.

Results: The mean intelligence quotient (IQ) of patients with VPI was 75.2±14.5 with a range between 41 and 107. The main defect was present in quantitative potential and then verbal ability followed by visual ability with memory having the highest mean. Patients with repaired cleft palate had the highest score (86.53±9.96), while the least score was reported among those with velopharyngeal disproportion (72.50± 9.59). There was a non-significant negative correlation between IQ degree and speech unintelligibility (p = 0.82).

Conclusion: About half of the patients with (VPI) have below average mentality. Patients with repaired cleft palate had the highest (IQ) score. Increased (IQ) score was accompanied by decreased speech unintelligibility, although it does not reach the level of significance.

 

Research Authors
Essam Eldin M. Aref1, Zeinab A. Abdel Hameed1 and Hanan A. Mohamed1
Research Date
Research Journal
The Egyptian Journal of Otolaryngology
Research Publisher
The Egyptian Journal of Otolaryngology
Research Rank
q4
Research Vol
35
Research Year
2023

Proton pump inhibitors as treatment of laryngeal disorders among patients with gastroesophageal reflux disease: asingle‑arm (pre and post) quasi-experimental study

Research Abstract

Objective: Laryngopharyngeal reflux is a silent cause of laryngeal disorders which was documented in the last decade by many studies. This study aimed to evaluate the prevalence of laryngeal reflux in GERD cases and to evaluate the effect of GERD treatment on these laryngeal disorders.

Patients and Methods: In this single-arm (pre and post) quasi-experimental study, eighty patients with GERD were examined for laryngeal disorders by rigid laryngoscopy and assessed by the Reflux Finding Score (RFS). Complaints of patients were evaluated using the 9-item Reflux Symptom Index (RSI) questionnaire. Patients received medical treatment of GERD in the form of proton pump inhibitors (PPIs) only, and they were reassessed after 3 months for improvement in their symptoms and signs using RSI and RFS systems to compare patient complaints and findings in the laryngeal endoscopy pre- and post-treatment.

Results: Among 80 confirmed GERD cases, 70 (87.5%) suffered from laryngeal disorders. Throat clearing and postnasal drip were the most prevalent symptoms, and ventricular obliteration and erythema, vocal fold and diffuse laryngeal edema, and posterior commissure hypertrophy were the most detected signs. Significant improvement in both symptoms and signs after 3 months of PPI therapy was clearly observed. The resistance rate among our studied patients was reported to be 22.4%.

Conclusion: GERD can be considered as an inducer or cause of laryngeal disorders, with a significant direct proportional relationship between the severity of GERD and both the RSI and RFS. PPI greatly improves laryngeal disorders among GERD patients with a high response rate (77.6%).

 

Research Authors
Mahmoud Ali Ragaee1*, Shaimaa Salah Sedik*, Hanan Abd El Rasheed Mohamed Ahmed**,Essam Eldeen Mohamed Osman Mahran*** and Mohamed Mahmoud Roushdy*
Research Date
Research Pages
1-9
Research Publisher
The Egyptian Journal of Otolaryngology
Research Vol
39
Research Year
2023

The Impact of Insulin-like Growth Factor-1, Growth Hormone, and Oxidative Stress in the Experimental Model of Juvenile and Adult Hypothyroid Retinal Degeneration

Research Authors
Omyma G Ahmed, Amal Taha and Faten Y Mahmoud
Research Date
Research Department
Research Member
Research Year
2011

Association between serum IGF-1, TNF-α, IL-6 and lipids with serum iron in both acute myocardial infarction and unstable angina patients

Research Authors
Omyma Ahmed; Ramadan Sayed; Osama Ibrahiem
Research Date
Research Department
Research Journal
Bulletin of Egyptian Society for physiological sciences
Research Member
Research Year
2007
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