This paper aims to measure the footprint for construction materials and construction and demolition waste (CDW) environmental impacts for a case study building in Egypt through the complete Life Cycle Assessment (LCA) of the building ‘from cradle to grave’. The LCA measures eight impact categories, including carbon emissions and energy demand. Our analysis demonstrates the relative importance of life cycle stages; construction processes and materials manufacturing that make the largest contributions to the buildings’ environmental impacts. The results show that the material manufacturing stage is the most critical stage because of its high contribution (about 70%) of the total environmental impacts. On the other hand the disposal stage contributes (about -10%). The results can help engineers and construction industry stakeholders in Egypt to use more sustainable construction materials and change their CDW management practice.