First Year Timetable is now Available
First Year timetable for the academic year 2022/2023 is now available.
The Second Call from Science, Technology, and Innovation Funding Authority Scholarship is Now Available
The Science, Technology, and Innovation Funding Authority Scholarship for researchers is now available. You can apply online using this link:
The deadline will be on 10 th October 2022.
For more information, kindly read the provided announcement.
Important Announcement for Locker Inventory
After checking the locker inventory in the Faculty of Dentistry, it has been found that 125 lockers are closed without submitting their keys to the public service office. As a result, the faculty calls those students to contact the public service office before breaking these lockers. The deadline before taking this legal procedure will be on Thursday 15-9-2022.
For more information about the number of these lockers, please check the above announcement.
Welcome Reception Party for New Students
The Faculty of Dentistry held a welcome reception party for its students on the 5th of September 2022. In addition, the medical examination of the students was also taken place in the examination halls on the same day
Registration for the 5th Graduation Party is Now Available
Genistein anticancer efficacy during induced oral squamous cell carcinoma: an experimental study
Research Abstract
Background: About 7 million people die from various types of cancer every year representing nearly 12.5% of deaths worldwide. This fact raises the demand to develop new, effective anticancer, onco-suppressive, and chemoprotective agents for the future fighting of cancers. Genistein exhibits pleiotropic functions in cancer, metabolism, and inflammation. It functions as an antineoplastic agent through its effect on the cell cycle, apoptotic processes, angiogenesis, invasion, and metastasis.
Aim of the study: The current study aimed to study the genistein onco-suppressive effects during 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamsters’ buccal pouch utilizing flow cytometry analysis (FMA), as a fast-diagnosing tool, in addition to the histopathology.
Material and methods: The buccal mucosa of adult male Syrian hamsters was painted with paraffin oil only (group 1), DMBA mixed in mineral oil (group 2), or orally administrated genistein along with painting DMBA (group 2B). The buccal mucosa was utilized for flow cytometric analysis and histopathological examination.
Results: Grossly, DMBA-induced carcinogenesis started at the 9th week. Progressive signs appeared in the following weeks reaching to large ulcerative oral masses and exophytic nodules at the 21st week. Histologically, invasive well differentiated oral squamous cell carcinoma (OSCC) appeared in the underlying tissues from the 12th week, showing malignant criteria. Genistein had delayed clinicopathological change, which started 6 weeks later, than the DMBA painted hamsters, as mild epithelial dysplastic changes. This became moderate during the last 6 weeks, without dysplastic changes. Flow cytometry revealed that DMBA led to considerable variation in DNA proliferation activity,aneuploid DNA pattern, in 47.22% of hamsters and significantly raised the S-phase fragment (SPF) values, which drastically reduced after genistein treatment.
Conclusion: Taken together, genistein could be employed as an onco-suppressive agent for carcinogenesis. Moreover, FMA could be used as an aiding fast tool for diagnosis of cancer.
Research Date
Research Department
Research File
Research Journal
Journal of the Egyptian National Cancer Institute
Research Member
Research Pages
1-10
Research Publisher
National Cancer Institute, Egypt
Research Vol
34
Research Website
https://doi.org/10.1186/s43046-022-00140-5
Research Year
2022
Important Announcement for Faculty Members about COP-27 Egypt Projects
In light of hosting COP-27 that will take place in Sharm El Sheikh next November, COP27 Egyptian presidency announced the launching of an initiative to enhance investments in different climate action sectors. The initiative aims at projects that could reduce pollution and the emission of carbon and protect the natural resources. In order to register in one of the mentioned projects in the announcement, please visit this link: www.sgg.eg
The website for these projects will start working from Sunday 21 August 2022 until Wednesday 7 September 2022.
Important Announcement for New Students about Registration and Medical Examinations
New students are asked to submit their required documents to join the faculty of dentistry on Monday 5-9-2022 and the medical examination for them will be set on the same day.
Assiut University Renewed Confidence for Prof/Nagla Elmelegy and Prof/ Heba Rashed
The Youth Affairs Office offers its congratulations to Prof/ Naglaa Taha Elmelegy -Vice Dean for Education and Student Affairs and Prof/ Heba Rashed - Vice Dean for Community Services and Environmental Development for renewing confidence in them wishing them all the best.
The Required Documents to Apply to The Faculty of Dentistry for the Academic Year 2022/2023
The above announcement demonstrates the required documents to apply to the faculty of Dentistry for the academic year 2022/2023. N.B. Folders that miss any required documents will not be accepted.