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Flavonoids and cyanogenic glycosides from the leaves and stem bark of Prunus persica (L.) Batsch (Meet Ghamr) peach local cultivar in Assiut region

Research Abstract
Mandelonitrile--D-glucopyranoside (prunasin) (1), kaempferol- 3-O--D-galactopyranoside (2), kaempferol-3-O--D-glucopyranoside (3), quercetin-3-O--D-glucopyranoside (4), mandelic acid amide--D-glucopyranoside (5), kaempferol-3-O-[-D-glucopyranosyl-(14)--D-galactopyranoside] (6), mandelonitrile--D-glucopyranosyl-(16)- -D- glucopyranoside (amygdalin) (7) were isolated from the methanolic extract of the leaves of Prunus persica (L.) Batsch “Meet Ghamr” peach. Furthermore, persicogenin (8), naringenin (9), aromadenderin (10), eriodictyol (11), persicogenin-3-O--D-glucopyranoside (12) and hesperitin-5-O--D-glucopyranoside (13) were isolated from the methanolic extract of the stem bark of the title plant. All these compounds were isolated for the first time from “Meet Ghamr“ peach while compounds 5 and 6 were firstly reported from the genus Prunus. Identification of these compounds has been established by physical, chemical and spectral methods (UV, IR, FAB-MS, 1-D-and 2-D NMR).
Research Authors
Enaam Y. Backheet, Salwa F. Farag, Amany S. Ahmed and Hanaa M. Sayed
Research Department
Research Journal
Bulletin of Pharmaceutical Sciences
Research Member
Research Publisher
Assiut University
Research Rank
2
Research Vol
26 (1)
Research Year
2003

Flavonoids and cyanogenic glycosides from the leaves and stem bark of Prunus persica (L.) Batsch (Meet Ghamr) peach local cultivar in Assiut region

Research Abstract
Mandelonitrile--D-glucopyranoside (prunasin) (1), kaempferol- 3-O--D-galactopyranoside (2), kaempferol-3-O--D-glucopyranoside (3), quercetin-3-O--D-glucopyranoside (4), mandelic acid amide--D-glucopyranoside (5), kaempferol-3-O-[-D-glucopyranosyl-(14)--D-galactopyranoside] (6), mandelonitrile--D-glucopyranosyl-(16)- -D- glucopyranoside (amygdalin) (7) were isolated from the methanolic extract of the leaves of Prunus persica (L.) Batsch “Meet Ghamr” peach. Furthermore, persicogenin (8), naringenin (9), aromadenderin (10), eriodictyol (11), persicogenin-3-O--D-glucopyranoside (12) and hesperitin-5-O--D-glucopyranoside (13) were isolated from the methanolic extract of the stem bark of the title plant. All these compounds were isolated for the first time from “Meet Ghamr“ peach while compounds 5 and 6 were firstly reported from the genus Prunus. Identification of these compounds has been established by physical, chemical and spectral methods (UV, IR, FAB-MS, 1-D-and 2-D NMR).
Research Authors
Enaam Y. Backheet, Salwa F. Farag, Amany S. Ahmed and Hanaa M. Sayed
Research Department
Research Journal
Bulletin of Pharmaceutical Sciences
Research Publisher
Assiut University
Research Rank
2
Research Vol
26 (1)
Research Year
2003

Flavonoids and cyanogenic glycosides from the leaves and stem bark of Prunus persica (L.) Batsch (Meet Ghamr) peach local cultivar in Assiut region

Research Abstract
Mandelonitrile--D-glucopyranoside (prunasin) (1), kaempferol- 3-O--D-galactopyranoside (2), kaempferol-3-O--D-glucopyranoside (3), quercetin-3-O--D-glucopyranoside (4), mandelic acid amide--D-glucopyranoside (5), kaempferol-3-O-[-D-glucopyranosyl-(14)--D-galactopyranoside] (6), mandelonitrile--D-glucopyranosyl-(16)- -D- glucopyranoside (amygdalin) (7) were isolated from the methanolic extract of the leaves of Prunus persica (L.) Batsch “Meet Ghamr” peach. Furthermore, persicogenin (8), naringenin (9), aromadenderin (10), eriodictyol (11), persicogenin-3-O--D-glucopyranoside (12) and hesperitin-5-O--D-glucopyranoside (13) were isolated from the methanolic extract of the stem bark of the title plant. All these compounds were isolated for the first time from “Meet Ghamr“ peach while compounds 5 and 6 were firstly reported from the genus Prunus. Identification of these compounds has been established by physical, chemical and spectral methods (UV, IR, FAB-MS, 1-D-and 2-D NMR).
Research Authors
Enaam Y. Backheet, Salwa F. Farag, Amany S. Ahmed and Hanaa M. Sayed
Research Department
Research Journal
Bulletin of Pharmaceutical Sciences
Research Member
Research Publisher
Assiut University
Research Rank
2
Research Vol
26 (1)
Research Year
2003

Isoflavonoids and flavone glycosides from rhizomes of Iris carthaliniae

Research Abstract
Two new isoflavonoid biosides, tectorigenin 4′-glucosyl (1→6)glucoside and iristectorigenin B 7-glucosyl (1→6)glucoside, a new isoflavonoid monoside, 4′-methyltectorigenin 7-glucoside and a new flavone glucoside, 6,4′-dimethoxy-5-hydroxyflavone 7-glucoside, together with tectoridin and tectorigenin 4′-glucoside were isolated from rhizomes of Iris carthaliniae. The structures of the isolated compounds were determined by NMR spectral analysis.
Research Authors
Salwa F. Farag, Enaam Y. Backheet, Nasr A. El-Emary and Masatake Niwa
Research Department
Research Journal
Phytochemistry
Research Member
Nasr Ahmed Mohammed Al Amri
Research Publisher
Elsevier
Research Rank
1
Research Vol
50 (8)
Research Year
1999

Isoflavonoids and flavone glycosides from rhizomes of Iris carthaliniae

Research Abstract
Two new isoflavonoid biosides, tectorigenin 4′-glucosyl (1→6)glucoside and iristectorigenin B 7-glucosyl (1→6)glucoside, a new isoflavonoid monoside, 4′-methyltectorigenin 7-glucoside and a new flavone glucoside, 6,4′-dimethoxy-5-hydroxyflavone 7-glucoside, together with tectoridin and tectorigenin 4′-glucoside were isolated from rhizomes of Iris carthaliniae. The structures of the isolated compounds were determined by NMR spectral analysis.
Research Authors
Salwa F. Farag, Enaam Y. Backheet, Nasr A. El-Emary and Masatake Niwa
Research Department
Research Journal
Phytochemistry
Research Member
Research Publisher
Elsevier
Research Rank
1
Research Vol
50 (8)
Research Year
1999

Isoflavonoids and flavone glycosides from rhizomes of Iris carthaliniae

Research Abstract
Two new isoflavonoid biosides, tectorigenin 4′-glucosyl (1→6)glucoside and iristectorigenin B 7-glucosyl (1→6)glucoside, a new isoflavonoid monoside, 4′-methyltectorigenin 7-glucoside and a new flavone glucoside, 6,4′-dimethoxy-5-hydroxyflavone 7-glucoside, together with tectoridin and tectorigenin 4′-glucoside were isolated from rhizomes of Iris carthaliniae. The structures of the isolated compounds were determined by NMR spectral analysis.
Research Authors
Salwa F. Farag, Enaam Y. Backheet, Nasr A. El-Emary and Masatake Niwa
Research Department
Research Journal
Phytochemistry
Research Publisher
Elsevier
Research Rank
1
Research Vol
50 (8)
Research Year
1999

Isoflavonoid glycosides from Dalbergia sissoo

Research Abstract
wo isoflavone glycosides, biochanin A 7-O-[beta-D-apiofuranosyl-(1-->5)-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside] and tectorigenin 7-O-[beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside], were isolated from Dalbergia sissoo. Their structures were elucidated on the basis of spectral and chemical evidence.
Research Authors
Salwa F. Farag, Amany S. Ahmed, Kenji Terashima, Yoshiaki Takaya and Masatake Niwa
Research Department
Research Journal
Phytochemistry
Research Member
Research Publisher
Elsevier
Research Rank
1
Research Vol
57(8)
Research Year
2001

Isoflavonoid glycosides from Dalbergia sissoo

Research Abstract
wo isoflavone glycosides, biochanin A 7-O-[beta-D-apiofuranosyl-(1-->5)-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside] and tectorigenin 7-O-[beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside], were isolated from Dalbergia sissoo. Their structures were elucidated on the basis of spectral and chemical evidence.
Research Authors
Salwa F. Farag, Amany S. Ahmed, Kenji Terashima, Yoshiaki Takaya and Masatake Niwa
Research Department
Research Journal
Phytochemistry
Research Member
Research Publisher
Elsevier
Research Rank
1
Research Vol
57(8)
Research Year
2001

Investigation of essential oil and biological activities of Lantana montevidensis (Spreng.) Briq. cultivated in Egypt.

Research Abstract
Background:Lantana montevidensis(L. montevidensis)is native to Brazil, the tea and infusions of the dried leaves have been used in folk medicine. Previous study of L. montevidensis leaves has resulted in the isolation of ten anti-proliferative flavones. Also, the essential oil of the Brazilian L. montevidensis leaves was investigated for its chemical composition and antimicrobial activity. Furthermore, the ethanolic extracts of the leaves and roots demonstrated anti-bacterial activity. Materials and Methods: The essential oils extracted by hydrodistillation from the Egyptian L. montevidensis leaves and flowers were investigated for their chemical composition. Also, a qualitative phytochemical analysis of 70% aqueous methanolic extract of L. montevidensis leaves was performed for the detection of alkaloids, tannins, triterpenoids, steroids, flavonoids, anthraquinones, saponins, iridoids, carbohydrates and/or glycosides. Furthermore, the extracts from the leaves were assessed for their anti-inflammatory, anti-pyretic, analgesic, antioxidant and antibacterial activities. Results: The composition of the essential oils included large amount of sesquiterpenes, mainly caryophyllene (33.74%),ß-selinene (43.95%), germacrene-D (3.79%) and nerolidol (6.32%) in the oil of the leaves, while caryophyllene (42.38%), γ-terpinene (22.64%), D-germacrene (9.10 %) and nerolidol(7.09%) are major in the oil of the flowers. Phytochemical screening of 70% aqueous methanolic extract of L. montevidensis leaves revealed the presence of carbohydrates and/or glycosides, unsaturated sterols, triterpenoids and flavonoids in addition to traces of saponins and iridoids. Furthermore, the extracts from the leaves exhibited anti-inflammatory, anti-pyretic, analgesic, antioxidant and antibacterial activities. Conclusion: The obtained results may provide a support to explore the plant for isolation of the active constituents accountable for these activities.
Research Authors
Makboul A. Makboul, Ahmed A. Attia, Salwa F. Farag, Nesma M. Mohamed
Research Department
Research Journal
Journal of Natural Pharmaceuticals
Research Member
Research Publisher
Medknow Publications and Media Pvt. Ltd
Research Rank
1
Research Vol
4 (1)
Research Year
2013

Investigation of essential oil and biological activities of Lantana montevidensis (Spreng.) Briq. cultivated in Egypt.

Research Abstract
Background:Lantana montevidensis(L. montevidensis)is native to Brazil, the tea and infusions of the dried leaves have been used in folk medicine. Previous study of L. montevidensis leaves has resulted in the isolation of ten anti-proliferative flavones. Also, the essential oil of the Brazilian L. montevidensis leaves was investigated for its chemical composition and antimicrobial activity. Furthermore, the ethanolic extracts of the leaves and roots demonstrated anti-bacterial activity. Materials and Methods: The essential oils extracted by hydrodistillation from the Egyptian L. montevidensis leaves and flowers were investigated for their chemical composition. Also, a qualitative phytochemical analysis of 70% aqueous methanolic extract of L. montevidensis leaves was performed for the detection of alkaloids, tannins, triterpenoids, steroids, flavonoids, anthraquinones, saponins, iridoids, carbohydrates and/or glycosides. Furthermore, the extracts from the leaves were assessed for their anti-inflammatory, anti-pyretic, analgesic, antioxidant and antibacterial activities. Results: The composition of the essential oils included large amount of sesquiterpenes, mainly caryophyllene (33.74%),ß-selinene (43.95%), germacrene-D (3.79%) and nerolidol (6.32%) in the oil of the leaves, while caryophyllene (42.38%), γ-terpinene (22.64%), D-germacrene (9.10 %) and nerolidol(7.09%) are major in the oil of the flowers. Phytochemical screening of 70% aqueous methanolic extract of L. montevidensis leaves revealed the presence of carbohydrates and/or glycosides, unsaturated sterols, triterpenoids and flavonoids in addition to traces of saponins and iridoids. Furthermore, the extracts from the leaves exhibited anti-inflammatory, anti-pyretic, analgesic, antioxidant and antibacterial activities. Conclusion: The obtained results may provide a support to explore the plant for isolation of the active constituents accountable for these activities.
Research Authors
Makboul A. Makboul, Ahmed A. Attia, Salwa F. Farag, Nesma M. Mohamed
Research Department
Research Journal
Journal of Natural Pharmaceuticals
Research Publisher
Medknow Publications and Media Pvt. Ltd
Research Rank
1
Research Vol
4 (1)
Research Year
2013
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