Association of follicular helper T and follicular regulatory T cells with severity and hyperglycemia in hospitalized COVID-19 patients

Research Abstract

We aimed to determine the levels of follicular helper T (Tfh) and follicular regulatory T (Tfr) cells in COVID-19 patients and determine whether their levels correlated with disease severity and presence of hyperglycemia. This study was carried out in 34 hospitalized COVID-19 patients and 20 healthy controls. Levels of total circulating Tfh, inducible T-cell costimulator (ICOS)+ activated Tfh, and Tfr cells were assessed in all participants by flow cytometry. Total CD4+CXCR5+ Tfh cells and ICOS+Foxp3-activated Tfh cells increased and ICOS+Foxp3+ Tfr cells decreased in COVID-19 patients, especially in diabetic patients and those with severe disease. Activated ICOS+ Tfh cells were directly correlated with lactate dehydrogenase, D-dimer, ferritin, and respiratory rate and inversely correlated with the partial pressure of carbon dioxide. COVID-19 is associated with marked activation of Tfh cells and a profound drop in Tfr …

Research Authors
Asmaa M Zahran, Mona H Abdel-Rahim, Khalid A Nasif, Safinaz Hussein, Rania Hafez, Ahmad Bahieldeen Ahmad, Khaled Saad, Amira Elhoufey, Hosni AM Hussein, Ali A Thabet, Omnia El-Badawy
Research Date
Research Department
Department of public health
Research Journal
Virulence
Research Member
Amira Abdallah Hassan El- Houfey
Research Pages
569-577
Research Publisher
Taylor & Francis
Research Website
https://www.tandfonline.com/doi/full/10.1080/21505594.2022.2047506
Research Year
2022

t was done by the will of God Almighty Ethics Committee Board Meeting

                                          headed by          

Mrs. Professor Dr. Awatif Al-Sayed Ahmed Al-Sayed - Chairman of the Committee

In the presence of the faculty members and their assistants in the committee

This will happen, God Almighty willing, on Sunday 25-2-2023 AD

Meeting room, administrative building, Faculty of Nursing, Assiut University 

 

 

 

 

Library Committee meeting March 2024

 God willing, the Library Committee will meet

headed by

Mrs. Professor Dr. Samah Muhammad Abdullah - Dean of the College

This is Sunday,10/3/2024 AD, at the Faculty of Nursing, Assiut University

 

Internal and Surgical Nursing Department Council meeting, March 2024

God willing, a meeting of the Internal and Surgical Nursing Department Council will take place

headed by

Mrs. Professor Dr. Magda Ahmed Mohamed Mansour, Head of the Department of Internal and Surgical Nursing

In the presence of the faculty members and their assistants

In the department on Monday 4/3/2024,                                                               

Meeting room, administrative building, Faculty of Nursing, Assiut University

Critical Care Nursing Department Council meeting, March 2024

 

 

 

God willing, a meeting of the Critical Care and Emergency Nursing Department Council will take place

headed by

Mrs. Dr. Mervat Anwar Abdel Aziz Sayed - Head of Department

In the presence of the faculty members and their assistants in the department

This is on Monday 4/2/2024

Meeting room, administrative building, Faculty of Nursing, Assiut University

 

 

Nursing Administration Department Council meeting, March 2024

 It will be done, God willing

Nursing Administration Department Council meeting

headed by

Mrs. Professor Dr. Sahar Mohamed Morsi - Head of the Department

In the presence of the faculty members and their assistants in the department

This will happen, God Almighty willing, on Monday 4/2/2024 AD

Meeting room, administrative building, Faculty of Nursing, Assiut University 

 

Elderly Nursing Department Council meeting, March 2024

It will be done, God willing

Elderly Nursing Department Council meeting

headed by

Mrs. Professor Dr. Samah Muhammad Abdullah

Dear faculty members and their assistants in the department

This is on Wednesday 6/3/2024 AD

Meeting room, administrative building, Faculty of Nursing, Assiut University

 

Meeting of the Education and Student Affairs Committee, March 2024

God willing, the Education and Student Affairs Committee will meet

headed by

Mrs. Professor Dr. Fatima Rushdi Muhammad Ali - Vice Dean for Education and Student Affairs

This is On Sunday,10/3/2024 AD,, at twelve o’clock in the afternoon

Meeting room, administrative building, Faculty of Nursing, Assiut University

 

 

Cultural Relations Committee meeting, March 2024

 God willing, a meeting of the Cultural Relations Committee will take place

 Chaired by Mrs. Prof. Dr. Ikram Ibrahim Muhammad - Vice Dean of the College for Postgraduate Studies and Research

On Sunday,10/3/2024 AD, the meeting room - the administrative building - Faculty of Nursing - Assiut University.

At ten o'clock in the morning

 

 

Postgraduate Studies and Research Committee meeting, February 2024

God willing, the Graduate Studies Committee will meet

Chaired by Mrs. Prof. Dr. Ikram Ibrahim Muhammad - Vice Dean of the College for Postgraduate Studies and Research

On Sunday,10/3/2024 AD, the meeting room - the administrative building - Faculty of Nursing - Assiut University.

At exactly eleven o'clock in the morning

 

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