Abstract Back ground: Processing in bakery generates diverse risk on exposed workers. The Aim: assess knowledge, and practices of workers towards occupational hazards and safety measures in bakeries at Assuit city .Design: A descriptive design was utilized. Setting: it was conducted in bakeries at Assuit city .Sample:. A systematic sample was used for selecting the study bakeries. Convenient sample was used (total coverage) for workers in chosen bakeries. Each bakery had average between 7 to 9 workers The total number was 87 workers. Tools: Two tools were utilized; I - Interview Questionnaire Sheet about demographic data , workers' knowledge about occupational hazards, injuries facing the workers. Worker's knowledge about safety measures. II- Observational Checklist was used to assess workers for using safety measures in the bakeries. Results: They clear that 2.3 % of the studied workers mentioned poor lighting consider from physical hazards. It was noticed that 17.3% of them sit or lie down workers in a cool or shady area consider from first aid for excessive heat. It show that majority of studied workers done personal hygiene. Conclusion: The majority of the bakeries workers had unsatisfactory knowledge and practice about occupational hazard and safety measures in the bakeries. Recommendations: Programs of health education should be organized and directed for workers to increase their awareness about hazards and safety measures.