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Early living donor kidney transplantation: Mode of changes in serum creatinine level during the direct post-transplantation period up to discharge.

Research Abstract
Background and Objectives: Pre-kidney transplantation (pre-KT) duration of dialysis is the strongest modifiable risk factor for the KT outcome. Our aim is to trace the mode of changes of serum creatinine levels in early LDKT patients during the direct post-KT period. Patients and Methods: We prospectively followed the recipients of early LDKT; patients who received no dialysis (preemptive LDKT or group I) and those who received pre-KT dialysis ≤ 6 months (group II) in Misr Kidney Center and Giza Renal Center from June 2010 to June 2012. Means of serum creatinine levels were compared between the two groups at different time points through the direct post-KT period (days spent for reaching normal level, lowest level, abnormal rising attacks and level on discharge). Results: There were 30 patients in group I with a mean age of 43.7 years and 15 patients in group II with a mean age of 34.3 years. The means of days spent for reaching normal serum craetinine levels in group I (3.86 ± 5.20 days) and group II (3.36 ± 2.37 days) were similar (p=0.73). The mean of lowest serum creatinine levels were insignificantly lower in group I (0.93 ± 0.34 mg/dl) than in group II (1.05 ± 0.40 mg/dl) (p=0.28). The percentage of patients who exposed to attacks of abnormal serum creatinine level rising during the post-KT period was less in group I (10%) than in group II (33.4%), but was insignificant (p=0.054). Difference between means of serum creatinine levels on discharge in group I (1.07±0.63 mg/dl) and in group II (1.09±0.42 mg/dl) was insignificant (p=0.9). Conclusion: In the direct post-KT period, means of serum creatinine levels were insignificantly lower in PLDKT patients than in KT recipients after a period of pre-KT dialysis. They also, have less abnormal rising attacks.
Research Authors
Gadelkareem, RA; Hameed, DE; El-Taher, AM; El-Araby, AM; Mahmoud, MA; El-Haggagy, AA; Ramzy, MF
Research Department
Research Journal
The 48th Annual Meeting of the Egyptian Urological Association.
Research Pages
NULL
Research Publisher
NULL
Research Rank
3
Research Vol
NULL
Research Website
NULL
Research Year
2013

Early living donor kidney transplantation: Mode of changes in serum creatinine level during the direct post-transplantation period up to discharge.

Research Abstract
Background and Objectives: Pre-kidney transplantation (pre-KT) duration of dialysis is the strongest modifiable risk factor for the KT outcome. Our aim is to trace the mode of changes of serum creatinine levels in early LDKT patients during the direct post-KT period. Patients and Methods: We prospectively followed the recipients of early LDKT; patients who received no dialysis (preemptive LDKT or group I) and those who received pre-KT dialysis ≤ 6 months (group II) in Misr Kidney Center and Giza Renal Center from June 2010 to June 2012. Means of serum creatinine levels were compared between the two groups at different time points through the direct post-KT period (days spent for reaching normal level, lowest level, abnormal rising attacks and level on discharge). Results: There were 30 patients in group I with a mean age of 43.7 years and 15 patients in group II with a mean age of 34.3 years. The means of days spent for reaching normal serum craetinine levels in group I (3.86 ± 5.20 days) and group II (3.36 ± 2.37 days) were similar (p=0.73). The mean of lowest serum creatinine levels were insignificantly lower in group I (0.93 ± 0.34 mg/dl) than in group II (1.05 ± 0.40 mg/dl) (p=0.28). The percentage of patients who exposed to attacks of abnormal serum creatinine level rising during the post-KT period was less in group I (10%) than in group II (33.4%), but was insignificant (p=0.054). Difference between means of serum creatinine levels on discharge in group I (1.07±0.63 mg/dl) and in group II (1.09±0.42 mg/dl) was insignificant (p=0.9). Conclusion: In the direct post-KT period, means of serum creatinine levels were insignificantly lower in PLDKT patients than in KT recipients after a period of pre-KT dialysis. They also, have less abnormal rising attacks.
Research Authors
Gadelkareem, RA; Hameed, DE; El-Taher, AM; El-Araby, AM; Mahmoud, MA; El-Haggagy, AA; Ramzy, MF
Research Department
Research Journal
The 48th Annual Meeting of the Egyptian Urological Association.
Research Pages
NULL
Research Publisher
NULL
Research Rank
3
Research Vol
NULL
Research Website
NULL
Research Year
2013

Post-transplantation anemia in the first year after preemptive living donor kidney transplantation.

Research Abstract
Background and Objectives: Restoration of normal hemoglobin (Hb) level is an advantage of kidney transplantation (KT). Our aim is to study the magnitude of improvement in Hb levels during the first year of preemptive living donor kidney transplantation (PLDKT). Patients and Methods: We prospectively studied the Hb levels in two groups of KT patients in Misr Kidney Center and Giza Renal Center from June 2010 to June 2012. Group I included patients who received no pre-KT dialysis (PLDKT) and group II included patients who received pre-KT dialysis for ≤ 6 months. Hb levels were followed and compared directly before discharge and at 1, 3, 6, 9, and 12 months post-KT. Normal Hb level was defined as > 13 g/dl for males and > 12 g/dl for females. Results: Group I included 30 patients (20 males and 10 females) and group II included 15 patients (9 males and 6 females). On discharge means (± Standard Deviation) of Hb levels between group I (8.39 ± 1.04 g/dl) and group II (8.85 ± 1.52 g/dl) were similar (p=0.23). In group I and inspite of being below the normal values, means of Hb levels after 1, 3, 6, 9, and 12 months were 10.23±1.24 g/dl, 11.20±1.21 g/dl, 11.55±1.36 g/dl, 11.76±1.63 g/dl and 11.97±1.60 g/dl, respectively, with a significant improvement (p=0.00). In group II, means of Hb levels at the same time points were 10.13±1.85 g/dl, 11.55±1.11 g/dl, 12.43±1.33 g/dl, 12.63±1.44 g/dl and 13.07±1.40 g/dl, respectively, with a significant improvement (p=0.00) to reach the normal values after 6 months. The improvement in means of Hb levels were significantly better in group II after 6 months (p=0.048) and 12 months (p=0.048) than in group I. Conclusion: During the second half of the first post-KT year, the means of Hb levels improved significantly to normal values in group II and to near normal values in group I.
Research Authors
Gadelkareem, RA; Hameed, DE; El-Taher, AM; El-Araby, AM; Mahmoud, MA; El-Haggagy AAa, Ramzy MF
Research Department
Research Journal
The 48th Annual Meeting of Egyptian Urological Association
Research Pages
NULL
Research Publisher
NULL
Research Rank
3
Research Vol
NULL
Research Website
NULL
Research Year
2013

Post-transplantation anemia in the first year after preemptive living donor kidney transplantation.

Research Abstract
Background and Objectives: Restoration of normal hemoglobin (Hb) level is an advantage of kidney transplantation (KT). Our aim is to study the magnitude of improvement in Hb levels during the first year of preemptive living donor kidney transplantation (PLDKT). Patients and Methods: We prospectively studied the Hb levels in two groups of KT patients in Misr Kidney Center and Giza Renal Center from June 2010 to June 2012. Group I included patients who received no pre-KT dialysis (PLDKT) and group II included patients who received pre-KT dialysis for ≤ 6 months. Hb levels were followed and compared directly before discharge and at 1, 3, 6, 9, and 12 months post-KT. Normal Hb level was defined as > 13 g/dl for males and > 12 g/dl for females. Results: Group I included 30 patients (20 males and 10 females) and group II included 15 patients (9 males and 6 females). On discharge means (± Standard Deviation) of Hb levels between group I (8.39 ± 1.04 g/dl) and group II (8.85 ± 1.52 g/dl) were similar (p=0.23). In group I and inspite of being below the normal values, means of Hb levels after 1, 3, 6, 9, and 12 months were 10.23±1.24 g/dl, 11.20±1.21 g/dl, 11.55±1.36 g/dl, 11.76±1.63 g/dl and 11.97±1.60 g/dl, respectively, with a significant improvement (p=0.00). In group II, means of Hb levels at the same time points were 10.13±1.85 g/dl, 11.55±1.11 g/dl, 12.43±1.33 g/dl, 12.63±1.44 g/dl and 13.07±1.40 g/dl, respectively, with a significant improvement (p=0.00) to reach the normal values after 6 months. The improvement in means of Hb levels were significantly better in group II after 6 months (p=0.048) and 12 months (p=0.048) than in group I. Conclusion: During the second half of the first post-KT year, the means of Hb levels improved significantly to normal values in group II and to near normal values in group I.
Research Authors
Gadelkareem, RA; Hameed, DE; El-Taher, AM; El-Araby, AM; Mahmoud, MA; El-Haggagy AAa, Ramzy MF
Research Department
Research Journal
The 48th Annual Meeting of Egyptian Urological Association
Research Member
Research Pages
NULL
Research Publisher
NULL
Research Rank
3
Research Vol
NULL
Research Website
NULL
Research Year
2013

Post-transplantation anemia in the first year after preemptive living donor kidney transplantation.

Research Abstract
Background and Objectives: Restoration of normal hemoglobin (Hb) level is an advantage of kidney transplantation (KT). Our aim is to study the magnitude of improvement in Hb levels during the first year of preemptive living donor kidney transplantation (PLDKT). Patients and Methods: We prospectively studied the Hb levels in two groups of KT patients in Misr Kidney Center and Giza Renal Center from June 2010 to June 2012. Group I included patients who received no pre-KT dialysis (PLDKT) and group II included patients who received pre-KT dialysis for ≤ 6 months. Hb levels were followed and compared directly before discharge and at 1, 3, 6, 9, and 12 months post-KT. Normal Hb level was defined as > 13 g/dl for males and > 12 g/dl for females. Results: Group I included 30 patients (20 males and 10 females) and group II included 15 patients (9 males and 6 females). On discharge means (± Standard Deviation) of Hb levels between group I (8.39 ± 1.04 g/dl) and group II (8.85 ± 1.52 g/dl) were similar (p=0.23). In group I and inspite of being below the normal values, means of Hb levels after 1, 3, 6, 9, and 12 months were 10.23±1.24 g/dl, 11.20±1.21 g/dl, 11.55±1.36 g/dl, 11.76±1.63 g/dl and 11.97±1.60 g/dl, respectively, with a significant improvement (p=0.00). In group II, means of Hb levels at the same time points were 10.13±1.85 g/dl, 11.55±1.11 g/dl, 12.43±1.33 g/dl, 12.63±1.44 g/dl and 13.07±1.40 g/dl, respectively, with a significant improvement (p=0.00) to reach the normal values after 6 months. The improvement in means of Hb levels were significantly better in group II after 6 months (p=0.048) and 12 months (p=0.048) than in group I. Conclusion: During the second half of the first post-KT year, the means of Hb levels improved significantly to normal values in group II and to near normal values in group I.
Research Authors
Gadelkareem, RA; Hameed, DE; El-Taher, AM; El-Araby, AM; Mahmoud, MA; El-Haggagy AAa, Ramzy MF
Research Department
Research Journal
The 48th Annual Meeting of Egyptian Urological Association
Research Pages
NULL
Research Publisher
NULL
Research Rank
3
Research Vol
NULL
Research Website
NULL
Research Year
2013

Post-transplantation anemia in the first year after preemptive living donor kidney transplantation.

Research Abstract
Background and Objectives: Restoration of normal hemoglobin (Hb) level is an advantage of kidney transplantation (KT). Our aim is to study the magnitude of improvement in Hb levels during the first year of preemptive living donor kidney transplantation (PLDKT). Patients and Methods: We prospectively studied the Hb levels in two groups of KT patients in Misr Kidney Center and Giza Renal Center from June 2010 to June 2012. Group I included patients who received no pre-KT dialysis (PLDKT) and group II included patients who received pre-KT dialysis for ≤ 6 months. Hb levels were followed and compared directly before discharge and at 1, 3, 6, 9, and 12 months post-KT. Normal Hb level was defined as > 13 g/dl for males and > 12 g/dl for females. Results: Group I included 30 patients (20 males and 10 females) and group II included 15 patients (9 males and 6 females). On discharge means (± Standard Deviation) of Hb levels between group I (8.39 ± 1.04 g/dl) and group II (8.85 ± 1.52 g/dl) were similar (p=0.23). In group I and inspite of being below the normal values, means of Hb levels after 1, 3, 6, 9, and 12 months were 10.23±1.24 g/dl, 11.20±1.21 g/dl, 11.55±1.36 g/dl, 11.76±1.63 g/dl and 11.97±1.60 g/dl, respectively, with a significant improvement (p=0.00). In group II, means of Hb levels at the same time points were 10.13±1.85 g/dl, 11.55±1.11 g/dl, 12.43±1.33 g/dl, 12.63±1.44 g/dl and 13.07±1.40 g/dl, respectively, with a significant improvement (p=0.00) to reach the normal values after 6 months. The improvement in means of Hb levels were significantly better in group II after 6 months (p=0.048) and 12 months (p=0.048) than in group I. Conclusion: During the second half of the first post-KT year, the means of Hb levels improved significantly to normal values in group II and to near normal values in group I.
Research Authors
Gadelkareem, RA; Hameed, DE; El-Taher, AM; El-Araby, AM; Mahmoud, MA; El-Haggagy AAa, Ramzy MF
Research Department
Research Journal
The 48th Annual Meeting of Egyptian Urological Association
Research Pages
NULL
Research Publisher
NULL
Research Rank
3
Research Vol
NULL
Research Website
NULL
Research Year
2013

Demographic characteristics of end-stage renal disease patients who access preemptive living donor kidney transplantation.

Research Abstract
Background and Objectives: Preemptive living-donor kidney transplantation (PLDKT) is the optimal treatment option for ESRD patients. Our aim is the description of the demographic characteristics of those patients that may encourage this therapeutic trend. Patients and Methods: We prospectively studied the recipients of PLDKT in Misr Kidney Center and Giza Renal center in the period from June 2010 to June 2012. We compared this group of PLDKT (group I) with another group of non-PLDKT recipients who received dialysis for ≤ 6 months (group II). In each group, we studied age [donors and recipients including recipient-donor age difference which was divided into positive (recipient older than donor) and negative (recipient younger than donor)], sex, education level, body weight and body mass index. Results: Group I included 30 PLDKT recipients (20 males and 10 females) with a mean age of 43.7 (7-62) years and mean donors age of 30 (21-44) years. Group II included 15 non-PLDKT recipients (9 males and 6 females) with a mean age of 34.3 (16-60) years and mean donors age of 28.4 (21-45) years. Recipient-donor age difference percentages as positive versus negative were, respectively, 93.3% versus 6.7% in group I and 60% versus 40% in group II. In group I, the high education level (university education or higher) represented 56.7%. However, in group II the middle education level (secondary school education) represented 53.3%. The mean body weight (76.18 kg and 78.4 kg) and mean body mass indices (26.6 kg/m2 and 27.4 kg/m2) were comparable between the two groups. Conclusion: Demographically, PLDKT recipients were older, have higher education levels than those recipients of non-PLDKT and relatively more old than their donors. However, both groups were comparable in percentages of recipient sex and means of body weight, body mass index and donors’ age.
Research Authors
Gadelkareem, RA; Hameed, DA; El-Taher, AM; El-Araby, AM; Mahmoud, MA; El-Haggagy, AA; Ramzy, MF
Research Department
Research Journal
The 48th annual meeting of the Egyptian Urological Association.
Research Pages
NULL
Research Publisher
NULL
Research Rank
3
Research Vol
NULL
Research Website
NULL
Research Year
2013

Demographic characteristics of end-stage renal disease patients who access preemptive living donor kidney transplantation.

Research Abstract
Background and Objectives: Preemptive living-donor kidney transplantation (PLDKT) is the optimal treatment option for ESRD patients. Our aim is the description of the demographic characteristics of those patients that may encourage this therapeutic trend. Patients and Methods: We prospectively studied the recipients of PLDKT in Misr Kidney Center and Giza Renal center in the period from June 2010 to June 2012. We compared this group of PLDKT (group I) with another group of non-PLDKT recipients who received dialysis for ≤ 6 months (group II). In each group, we studied age [donors and recipients including recipient-donor age difference which was divided into positive (recipient older than donor) and negative (recipient younger than donor)], sex, education level, body weight and body mass index. Results: Group I included 30 PLDKT recipients (20 males and 10 females) with a mean age of 43.7 (7-62) years and mean donors age of 30 (21-44) years. Group II included 15 non-PLDKT recipients (9 males and 6 females) with a mean age of 34.3 (16-60) years and mean donors age of 28.4 (21-45) years. Recipient-donor age difference percentages as positive versus negative were, respectively, 93.3% versus 6.7% in group I and 60% versus 40% in group II. In group I, the high education level (university education or higher) represented 56.7%. However, in group II the middle education level (secondary school education) represented 53.3%. The mean body weight (76.18 kg and 78.4 kg) and mean body mass indices (26.6 kg/m2 and 27.4 kg/m2) were comparable between the two groups. Conclusion: Demographically, PLDKT recipients were older, have higher education levels than those recipients of non-PLDKT and relatively more old than their donors. However, both groups were comparable in percentages of recipient sex and means of body weight, body mass index and donors’ age.
Research Authors
Gadelkareem, RA; Hameed, DA; El-Taher, AM; El-Araby, AM; Mahmoud, MA; El-Haggagy, AA; Ramzy, MF
Research Department
Research Journal
The 48th annual meeting of the Egyptian Urological Association.
Research Member
Research Pages
NULL
Research Publisher
NULL
Research Rank
3
Research Vol
NULL
Research Website
NULL
Research Year
2013

Demographic characteristics of end-stage renal disease patients who access preemptive living donor kidney transplantation.

Research Abstract
Background and Objectives: Preemptive living-donor kidney transplantation (PLDKT) is the optimal treatment option for ESRD patients. Our aim is the description of the demographic characteristics of those patients that may encourage this therapeutic trend. Patients and Methods: We prospectively studied the recipients of PLDKT in Misr Kidney Center and Giza Renal center in the period from June 2010 to June 2012. We compared this group of PLDKT (group I) with another group of non-PLDKT recipients who received dialysis for ≤ 6 months (group II). In each group, we studied age [donors and recipients including recipient-donor age difference which was divided into positive (recipient older than donor) and negative (recipient younger than donor)], sex, education level, body weight and body mass index. Results: Group I included 30 PLDKT recipients (20 males and 10 females) with a mean age of 43.7 (7-62) years and mean donors age of 30 (21-44) years. Group II included 15 non-PLDKT recipients (9 males and 6 females) with a mean age of 34.3 (16-60) years and mean donors age of 28.4 (21-45) years. Recipient-donor age difference percentages as positive versus negative were, respectively, 93.3% versus 6.7% in group I and 60% versus 40% in group II. In group I, the high education level (university education or higher) represented 56.7%. However, in group II the middle education level (secondary school education) represented 53.3%. The mean body weight (76.18 kg and 78.4 kg) and mean body mass indices (26.6 kg/m2 and 27.4 kg/m2) were comparable between the two groups. Conclusion: Demographically, PLDKT recipients were older, have higher education levels than those recipients of non-PLDKT and relatively more old than their donors. However, both groups were comparable in percentages of recipient sex and means of body weight, body mass index and donors’ age.
Research Authors
Gadelkareem, RA; Hameed, DA; El-Taher, AM; El-Araby, AM; Mahmoud, MA; El-Haggagy, AA; Ramzy, MF
Research Department
Research Journal
The 48th annual meeting of the Egyptian Urological Association.
Research Pages
NULL
Research Publisher
NULL
Research Rank
3
Research Vol
NULL
Research Website
NULL
Research Year
2013

Demographic characteristics of end-stage renal disease patients who access preemptive living donor kidney transplantation.

Research Abstract
Background and Objectives: Preemptive living-donor kidney transplantation (PLDKT) is the optimal treatment option for ESRD patients. Our aim is the description of the demographic characteristics of those patients that may encourage this therapeutic trend. Patients and Methods: We prospectively studied the recipients of PLDKT in Misr Kidney Center and Giza Renal center in the period from June 2010 to June 2012. We compared this group of PLDKT (group I) with another group of non-PLDKT recipients who received dialysis for ≤ 6 months (group II). In each group, we studied age [donors and recipients including recipient-donor age difference which was divided into positive (recipient older than donor) and negative (recipient younger than donor)], sex, education level, body weight and body mass index. Results: Group I included 30 PLDKT recipients (20 males and 10 females) with a mean age of 43.7 (7-62) years and mean donors age of 30 (21-44) years. Group II included 15 non-PLDKT recipients (9 males and 6 females) with a mean age of 34.3 (16-60) years and mean donors age of 28.4 (21-45) years. Recipient-donor age difference percentages as positive versus negative were, respectively, 93.3% versus 6.7% in group I and 60% versus 40% in group II. In group I, the high education level (university education or higher) represented 56.7%. However, in group II the middle education level (secondary school education) represented 53.3%. The mean body weight (76.18 kg and 78.4 kg) and mean body mass indices (26.6 kg/m2 and 27.4 kg/m2) were comparable between the two groups. Conclusion: Demographically, PLDKT recipients were older, have higher education levels than those recipients of non-PLDKT and relatively more old than their donors. However, both groups were comparable in percentages of recipient sex and means of body weight, body mass index and donors’ age.
Research Authors
Gadelkareem, RA; Hameed, DA; El-Taher, AM; El-Araby, AM; Mahmoud, MA; El-Haggagy, AA; Ramzy, MF
Research Department
Research Journal
The 48th annual meeting of the Egyptian Urological Association.
Research Pages
NULL
Research Publisher
NULL
Research Rank
3
Research Vol
NULL
Research Website
NULL
Research Year
2013
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