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Causes of peripheral hypotonia in infant and children attending Assiut university children hospital.
Research Abstract
Background: Diseases in the peripheral motor unit are common in children. The term peripheral hypotonia covers disorders of the neuromuscular unit other than causes in the Central Nervous System (CNS). This includes the peripheral motor unit with its four components: Anterior horn cell in the spinal cord, its axons with other axis forming the peripheral nerve (including the cranial nerves) and the neuromuscular junction with the muscle fibers innervated by a single motor neuron. The aim of this work is to give a profile of the causes of peripheral hypotonia in infants and children attending Assiut University Children Hospital. Patients and Methods: 32 patients aged over one month to 14 years were assessed clinically and had creatine kinase enzyme measured, as well as Nerve Conduction (NC) and Electromyography (EMG), together with muscle ultrasonography done. Results: Cases had Guillan-Barre Syndrome (GBS) in 56.3%, Duchene Muscular Dystrophy (DMD) in 21.9% and Spinal Muscular Atrophy (SMA) in 12.5%, and myositis in 9.4%. Ultrasonography showed sensitivity in the diagnosis of peripheral hypotonia in 96.43% and specificity of 75%, with positive and negative predictive values as 87.5% and 12.5% respectively. Conclusion: For neurological cases, hope is present with early discovery of spinal muscular atrophy in newborns by screening with ultrasonography with new treatment by gene therapy because of higher sensitivity and predictive value. Recommendations: A future study in peripheral hypotonia in pediatrics is recommended with a bigger number of cases to support this work.
Research Date
Research Department
Research Journal
Current pediatric research
Research Member
Research Pages
1279-1282
Research Publisher
Allied Academies
Research Vol
26
Research Website
DOI:10.35841/0971-9032.26.3.1279-1282.
Research Year
2022
Role of Doppler ultrasound in the evaluation of superficial soft tissue lesions
Research Abstract
Objectives
To evaluate the role of Doppler ultrasound (DUS) in the characterization of superficial soft tissue lesions using histopathological examination as a gold standard.
Patients and methods
Forty patients, mean age 37.43 ± 16.9 years complaining of superficial soft tissue swelling in any region of the body were prospectively included. Gray scale evaluation was performed and then color Doppler interrogation was applied to evaluate its vascularity and finally spectral Doppler analysis. DUS findings were subjected to histopathologic correlation.
Results
Five malignant and 35 benign lesions were histopathologically diagnosed. There was strong agreement (K = 0.89) between DUS impression and histopathological diagnosis (P < 0.001).
Conclusions
DUS can characterize the nature of superficial soft tissue lesions and discriminate benign from malignant.
Research Date
Research Department
Research Journal
Journal of Current Medical Research and Practice
Research Member
Research Pages
183-190
Research Publisher
Wolters Kluwer - Medknow
Research Vol
7
Research Website
DOI: 10.4103/jcmrp.jcmrp_96_21
Research Year
2022
Predictors of Subclinical Atherosclerotic Cardiovascular Disease in Inflammatory Bowel Disease Patients
Research Abstract
Inflammatory bowel disease (IBD) is a chronic intestinal disease that can be caused by a variety of environmental and genetic factors. Several processes that are chronically stimulated in IBD patients have been involved in the pathophysiology of atherosclerotic cardiovascular disease (ASCVD).
Research Date
Research Department
Research Journal
The Egyptian Journal of Hospital Medicine
Research Member
Research Pages
Pages 1666-1673
Research Publisher
Ain Shams University, Faculty of Medicine, Pan Arab League of Continuous Medical Education
Research Rank
Q4
Research Vol
Volume 87
Research Year
2022
[PDF] from ekb.eg Role of Intestinal Ultrasound with Doppler in Assessment of Inflammatory Bowel Disease
Research Abstract
accurate diagnosis of inflammatory bowel disease (IBD) are mandatory steps for a good outcome. Its standard method for assessment is still ileo-colonoscopy; however, many recent reports described the utility of intestinal ultrasound (IUS) and duplex US in evaluating patients with IBD. We aimed to explore the efficacy of IUS and duplex US for the accurate diagnosis and follow-up of patients with IBD.
Research Date
Research Department
Research Journal
The Egyptian Journal of Hospital Medicine
Research Member
Research Pages
Pages 1991-1999
Research Publisher
Ain Shams University, Faculty of Medicine, Pan Arab League of Continuous Medical Education
Research Vol
Volume 87
Research Year
2022
[HTML] from eg.net Vascular pattern and spectral parameters of Doppler ultrasound in differentiation between malignant and benign thyroid nodules
Research Abstract
Thyroid nodules are common pathologies detected in thyroid gland. A thyroid nodule is the manifestation of a wide range of thyroid diseases, some benign and others malignant. Currently, the use of imaging methods has increased the diagnosis of asymptomatic nodules. Ultrasound studies of the population have reported a nodular thyroid disease rate of nearly 67% in elderly women. Most of these nodules are benign, and the incidence of malignancy is low (3–7%).
Purpose
To evaluate the role of vascular pattern and spectral wave forms and resistivity and pulsatility indices to differentiate between malignant and benign features.
Research Date
Research Journal
Journal of Current Medical Research and Practice
Research Member
Research Pages
82
Research Publisher
Publisher Medknow Publications
Research Vol
volume 6
Research Year
2021
مرضي سيولة الدم والأدوية المستخدمة قبل وأثناء وبعد العملية وكيفية استخدام الطرق الأمنة لتفادي السيولة أو التجلط في الفترة المحيطة بالجراحة والتحديات التي تواجه اطباء الدم والحالات الحرجة والأوعية الدموية وأطباء التخدير والجراحة.
