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Genomic epidemiology and emergence of SARS-CoV-2 variants of concern in the United Arab Emirates

Research Authors
Habiba Alsafar, Mohammed Albreiki, Mira Mousa, Syafiq Kamarul Azman, Hema Vurivi, Fathimathuz Waasia, Dymitr Ruta, Farida Alhosani, Shereena Almazrouei, Rowan Abuyadek, Francis Selvaraj, Irene Chaves-Coira, Val Zvereff, Mohamed AY Abdel-Malek, Nawal Alkaa
Research Date
Research Journal
Scientific Reports
Research Publisher
Nature Publishing Group UK
Research Year
2022

Surgical hip dislocation in fixation of acetabular fractures: extended indications and outcome

Research Abstract
Surgical hip dislocation has been described as an excellent method for reduction and fixation of acetabular fractures. It allows a 360-degree access to the acetabulum and acetabular dome. However, reproducibility of this technique is still a concern. The primary outcome of this study was to investigate the short term functional and radiological outcome with the use of surgical hip dislocation in acetabular fractures. The secondary outcome was to describe different indications and methods of reduction using this technique.
Research Authors
Osama Ahmed Farouk
Research Date

Management of anterior associated types of acetabular fractures utilizing the modified Stoppa and the pararectus approaches: a prospective cohort study and early experience

Research Abstract

This study aimed to report the early experience (radiographic, functional, and complications outcomes) from an Egyptian (North African) level one trauma centre after utilizing the modified Stoppa and the pararectus approaches to manage anterior-associated types of acetabular fractures.

Patients and methods

Between January 2014 and April 2018, 63 patients (40 males and 23 females) with a mean age of 33 ± 11.5 were included, 45 patients were treated through the modified Stoppa (group A), and 18 through the pararectus approach (group B).

Results

At a mean follow-up of 32.11 ± 15.36 months (range 12 to 64), 56 patients (43 group A and 13 group B) were evaluated. The post-operative anatomical reduction was achieved in 44 (78.6%) patients. At the last follow-up, Matta radiological outcome grades were excellent and good in 50 (89.2%) patients, fair and poor in six (10.8%). The mean Harris Hip …

Research Authors
Ali Fergany, Ahmed A. Khalifa, Aly Mohamedean, Faisal Fahmy Adam, Osama Farouk
Research Date
Research Journal
International Orthopaedics
Research Year
2022

Surgical management of paediatric pelvic fractures: a prospective case series and early experience from a level one Egyptian trauma centre

Research Abstract

Purpose

We aimed to report our early experience treating paediatric pelvic fractures (PPF) surgically, reporting on indications, outcomes, and complications.

Methods

Patients aged 0–15 with PPF treated surgically at a level I trauma centre were included prospectively between 2016 and 2018. Fractures were classified according to AO/OTA classification system. Functional evaluation was performed using a modification of the Majeed functional scoring system. Radiological evaluation of vertical and posterior displacement was performed according to Matta and Tornetta criteria and the method described by Keshishyan et al. for assessing pelvic rotational asymmetry.

Results

We included 45 patients (77.8% males and 22.2% females), with a mean age of 9.53 ± 3.63 and 19.87 ± 8.84 months of mean follow-up. The functional outcome was excellent in 42 (93.3%) patients, good in two (4.4%), and fair in one (2.2%). Radiologically, the vertical displacement improved from 5.91 ± 4.64 to 3.72 ± 2.87 mm (p-value 0.065), the posterior displacement improved from 7.87 ± 8.18 to 5.33 ± 13.4 mm (p-value 0.031), and the symphyseal diastasis improved from 9.88 ± 7.51 mm to 7.68 ± 3.18 mm (p-value 0.071). Residual pelvic asymmetry improved from 1.2 ± 0.61 to 0.8 ± 0.7 (p-value 0.001). Complications occurred in 21 (46.7%) patients, 11 (24.4%) pin tract infection, six (13.3%) limb length discrepancy, two (4.4%) prominent metals, one (2.2%) subcutaneous haematoma, one (2.2%) infected ISS.

Conclusions

We achieved acceptable functional and radiological outcomes after surgically treating a group of patients with PPF, which was relatively safe with minimal complications. The proper approach and fracture fixation tool should be tailored according to the fracture classification and the presence of associated injuries.

Research Authors
أ.د.أسامة أحمد فاروق محمد عبدالعال
Research Date
Research Journal
International Orthopaedics
Research Pages
2315-2328
Research Publisher
Springer Berlin Heidelberg
Research Website
https://link.springer.com/article/10.1007/s00264-022-05509-8
Research Year
2022

College Council Meeting (No. 780) Monday, March 25, 2020

College Council Meeting (No. 780) Monday, March 25, 2020

برئاسة الأستاذ الدكتور/ علاء عطية- عميد الكلية و رئيس مجلس إدارة المستشفيات الجامعية - و بحضور السادة وكلاء الكلية والسيد المدير التنفيذي للمستشفيات الجامعية ، والسيد وكيل وزارة الصحة، والسيد نقيب اطباء اسيوط ، والسادة رؤساء الأقسام بالكلية والسادة أعضاء المجلس.

في البداية رحب السيد عميد الكلية بالسادة أعضاء المجلس وقدم لهم التهنئة علي نجاح مؤتمر الكلية الرابع والثلاثون الذي اقيم في الفترة (من ٥-٧ مارس) , تحت عنوان "الجوانب الغذائية للأمراض المختلفة"، وشكر لهم مجهودهم في هذا النجاح.

ومن ثم بدأ المجلس باستعراض انجازات الكلية خلال الشهر الماضي،وقام المجلس بالنظر في الموضوعات المعروضة عليه بجدول الأعمال فيما يخص موضوعات المصادقة و الإحاطة، من موضوعات شئون

أعضاء هيئة التدريس و موضوعات قطاع الدراسات العليا، وموضوعات قطاع شئون التعليم والطلاب وقطاع خدمة المجتمع وتنمية البيئة

 

Prevalence and characteristics of multifocal choroiditis/punctate inner choroidopathy in pathologic myopia eyes with patchy atrophy

Research Abstract

Purpose:

To determine the prevalence and characteristics of multifocal choroiditis/punctate inner choroidopathy (MFC/PIC) in eyes with patchy atrophy because of pathologic myopia.

Methods:

Five hundred eyes of 253 patients with patchy atrophy were examined between 2014 and 2020 at the Advanced Clinical Center for Myopia. The main outcome measures included the prevalence and characteristics of active MFC/PIC lesions diagnosed by optical coherence tomography.

Results:

Fifty-five of the 500 eyes (11%) diagnosed with patchy atrophy had optical coherence tomography features of active MFC/PIC lesions, such as focal elevations of the retinal pigment epithelium filled with medium hyperreflectivity material, curvilinear scars (Schlaegel lines), and/or areas of outer retinal atrophy. At the time when the MFC/PIC was diagnosed, the mean age was 57.3±12.0 years, and the mean axial length was 29.2±1.8 mm …

Research Authors
Shymaa K Hady, Shiqi Xie, K Bailey Freund, Emmett T Cunningham Jr, Chee Wai Wong, Chui Ming Gemmy Cheung, Koju Kamoi, Tae Igarashi-Yokoi, Omar M Ali, Ehab I Wasfi, Mahmoud F Rateb, Kyoko Ohno-Matsui
Research Date
Research Department
Research Journal
Retina
Research Year
2022

Impact of COVID-19 on children with rheumatic diseases: a retrospective cohort analysis

Research Abstract



Background: Data concerning impact of COVID-19 on children with rheumatic disorders in developing countries are limited.
Methods: We conducted a retrospective analysis, examining the medical records of 49 children (15 males, 34 females) with rheumatologic disorders who got infected with SARS-CoV2. They were recruited, over a period of 17 months, from the Children’s Hospitals of Ain Shams, Mansoura and Assiut Universities in Egypt. Data recorded were the type and duration of rheumatologic, antirheumatic treatment received, and COVID-19 presentation including severity, and outcome. Complete blood count (CBC), erythrocyte sedimentation rate (ESR), C reactive protein (CRP), lactate dehydrogenase enzyme (LDH), serum ferritin, and D-dimer levels were recorded.
Results: Our series included 25 SLE, 16 JIA, two polyarteritis nodosa, two dermatomyositis, two mixed connective tissue disease, one systemic sclerosis, and one HSP patients. They had median (IQR) age of 13 (10-14) years. Twenty-nine (59.2%) patients had active disease flare. Forty-one (83.7%) patients were on corticosteroids, and 35 (71.4%) were on add-on immunosuppressives. Twenty-nine patients were hospitalized with median (IQR) admission duration of 25 (14-38) days. They included 8 mild/asymptomatic, 4 moderate, 6 severe, and 11 critical COVID-19 cases. Seven cases with critical COVID-19 passed away with mortality rate of 14.3 %. The deceased cases had higher neutrophil/lymphocyte ratio (p=0.003), higher CRP levels (p= 0.041) and higher D-dimer (p=0.001) and ferritin levels (0.002) as compared to survivors.
Conclusion: Although reported to be milder in children, COVID-19 seems to have higher mortality among children with rheumatic disorders compared to rates reported in the general population. We could not find evidence for the impact of immunosuppressive treatment on COVID-19 related mortality, yet our findings need to be validated by wider scale prospective studies .
Keywords: COVID-19; rheumatic diseases; mortality; children; pediatric; hospitalized, outcomes.

Research Authors
Rasha El-Owaidy1, Elham Hossny1, Dalia El-Ghoneimy1, Zeinab A. El-Sayed1, Shereen Reda1, Ihab Elhakim2, Hanan Ibrahim3, Iman Ragab4, Nesrine Radwan1, Ghada Shousha1, Amal Lotfy1, Amr Elmekkawy1, Ali Sobh5, Naglaa Osman6, Mariam Abdelnaby1, Roba Al-Gaweesh
Research Date
Research Department
Research File
Research Journal
Egypt Journal of Pediatric Allergy and Immunology
Research Member
Research Pages
69-77
Research Vol
20
Research Website
https://dx.doi.org/10.21608/ejpa.2022.264504
Research Year
2022

Burnout syndrome (BOS) among resident doctors in an Egyptian tertiary care university hospital: Prevalence and determinants during the COVID-19 pandemic

Research Abstract

Objectives: The current study aimed to detect the BOS prevalence and determinants among residents working during the second wave of the COVID-19 pandemic in an Egyptian tertiary university referral hospital. Methods: A crosssectional study evaluating the working period from June to November 2020 during the COVID-19 pandemic second wave, through a five sections questionnaire evaluating: 1 − sociodemographic characteristics, 2 − job characteristics, 3 − negative thoughts related to their job, 4 − resident’s health problems, and 5 − evaluating BOS through Maslach Burnout Inventory (MBI) scale (including emotional exhaustion [EE], depersonalization [DP], and personal accomplishment [PA] as subscales). Results: We included 230 residents with a median age of 27 years. The median MBI sub-scales (IQ Range) values were 30.0 (20, 39), 21.0 (15, 30), and 29.5 (22, 36) for EE, DP, and PA, respectively. About 51.0% and 83.0% of the residents were high in EE and DP, while 8.7% were low in PA. The median EE and DP were higher in younger age (⩽27 years; p=.002 and .024), males (p=.001 and 90 hours weekly (p=.016 and <.001), exposure to harassment (p<.001), and having COVID-19 infection (p=.002 and .001). Residents working in surgical departments reported higher DP scores than those in non-surgical departments (p=.03). There was a mild positive correlation between working hours per week and the total scores in EE and DP, r=.24 (p<.001) and r=.23 (p=.001) respectively, while it was found to have a negative correlation with the PA (r=−.133 and p=.044). Conclusions: The BOS is evident and considerably high among the residents working during the COVID-19 pandemic. Younger age, males, working in surgical departments, and those who got COVID-19 infection were most vulnerable.

Research Authors
Amr A. Fadle, Ahmed A Khalifa , Dalia G. Mahran, Shimaa Sayed Khidr, Hatem G Said and Osama Farouk
Research Date
Research Journal
International Journal of Social Psychiatry
Research Pages
396-405
Research Publisher
SAGE Publications
Research Vol
69 (2)
Research Year
2022
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