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EVALUATION OF SALVIA ROSMARINUS AND CORIANDRUM SATIVUM AS CHEMOPREVENTIVE AGENTS IN INDUCED ORAL SQUAMOUS CELL CARCINOMA (AN EXPERIMENTAL STUDY)

Research Abstract
Abstract
Introduction: The most prevalent malignant tumor of the head and neck region is squamous cell carcinoma. The bad prognosis and low survival rate are mainly related to oral cancer patients. Developing chemopreventive techniques has been crucial to reduce the incidence of oral cancer. Chemoprevention with natural products has emerged as viable preventive options. Salvia rosmarinus and Coriandrum sativum have been studied and discovered to have powerful anticancer properties.
Aim of the study: The present trial was proceeded to study the effects of salvia rosmarinus and coriandrum sativum during experimental hamster buccal pouch carcinoma induction; using PCNA as cancer proliferative cell marker.
Material and Methods: A total of 60 adult male hamsters were divided into 5 equal groups. Group I, biopsies of normal pouch mucosa were obtained as a negative control. All remaining groups were painted by DMBA as a carcinogenic agent. Group II, as a positive control group, was only painted by DMBA. Group III received topically salvia rosmarinus oil. Group IV received topically coriandrum sativum oil. Group V received both oils together. After 16, 24, and 32 weeks, 2 to 4 animals from every group had been sacrificed. Tissue lesions were prepared, and paraffin sections were stained with primary antibody for PCNA immunohistochemical evaluation.
Results: The salvia rosmarinus and coriandrum sativum; either alone or in combination, significantly reduced the carcinogenic effect for DMBA-induced oral carcinogenesis.
Conclusion: Salvia rosmarinus and coriandrum sativum have a chemopreventive considerable action versus oral cancer development, and their synergetic action is considerably more effective.
Research Authors
Amr Abdelmoez email ; Hanaa Raslan; Nesrin Hassan; Asmaa Zahran; Ahmed Mohammad Hussein
Research Date
Research Department
Research Publisher
Alexandria Dental Journal
Research Website
DOI: 10.21608/ADJALEXU.2024.299564.1516
Research Year
2024

Validation of novel measurement protocols proposed for the standardized assessment of crestal bone levels: A cone-beam computed tomography study

Research Abstract

ABSTRACT

Purpose: This study was performed to introduce, evaluate, and compare various novel assessment protocols designed for straightforward, reliable, and reproducible measurement of alveolar bone levels. These protocols are intended for standardized periodontal assessment and follow-up, utilizing cone-beam computed tomography (CBCT) images and manipulation of Digital Imaging and Communications in Medicine (DICOM) viewer software.

Materials and Methods: Two experienced oral and maxillofacial radiologists developed 5 distinct radiographic measurement protocols. These techniques were established to assess the alveolar bone level of a periodontally affected upper central incisor using a method that is consistently repeatable across observers. Two additional assessors, blinded to the details of the study, independently applied the protocols to retrieved DICOM files that met the eligibility criteria. A scoring system with 3 subscores was created and used to compare the protocols.

Results: Statistically excellent inter-observer reliability was observed for all protocols, other than protocol 1, which demonstrated moderate reliability. The average discrepancy between measurements taken by the 2 observers was 1.2 mm for protocol 1, 0.81 mm for protocol 2, and less than 0.5 mm for the remaining 3 protocols. All approaches except protocol 4 were straightforward to apply.

Conclusion: This study introduces multiple reliable protocols for the evaluation of periodontal bone levels that ensure consistency across observers. Based on the findings, the double axial lines and incisocrestal distance protocols are recommended. These new assessment approaches, along with any future modifications, may be useful in periodontal assessment, dental implant follow-up, orthodontic evaluation, research, and artificial intelligence model generation. (Imaging Sci Dent 20240073)

Research Authors
Ali Fahd1,*, Aya A. Hussien2, Mohamed T. Ellabban3, Zein A. Shatat4
Research Date
Research Department
Research Journal
Imaging Science in Dentistry
Research Publisher
Imaging Science in Dentistry
Research Website
https://www.researchgate.net/publication/384429687_Validation_of_novel_measurement_protocols_proposed_for_the_standardized_assessment_of_crestal_bone_levels_A_cone-beam_computed_tomography_study
Research Year
2024

Assessment of Nasopalatine Canal Anatomic Variations Using Cone Beam Computed Tomography in a sample of The Egyptian Population

Research Abstract

Abstract:

Background: This research was designed to assess the nasopalatine canal shape, size as well as anatomic variations according to age & gender in a sample of the Egyptian population utilising CBCT .

Material and Methods: This research was conducted on 100 CBCT scans belonging to 31 males & 69 women, with mean age of (35.8 ± 12.3) years. Inclusion and exclusion criteria as well as ethical issues were designed. CBCT scans were classified according to gender (male and female) and according to age (18-40 year and 41-61 year). All nasopalatine canals were evaluated to assess nasopalatine canal shape in coronal view and sagittal view as well as measurements of the nasopalatine canal in the sagittal & axial cross-section CBCT. The data were collected, computed, tabulated and statistically analyzed.

Results: Was observed no statistically substantial association amongst gender & NPC shape. Also, was noted no statistically substantial association amongst age group and NPC shape. Males showed statistically significantly higher mean diameter of incisive foramen and nasopalatine canal length than females. Subjects aged 18 – 40 years old showed statistically significantly lower mean antero-posterior diameter of nasal foramen, medio-lateral diameter of incisive foramen as well as canal diameter than those aged 41 – 61 years old.

Conclusions: The most frequent NPC shape in coronal view is variation of the Y-type of NPC in half of participants followed by single canal and the least was 2 parallel canals. The most frequent NPC shape in sagittal view is funnel shape (29%) followed by cylindrical shape (28%). The antero-posterior diameter of the incisive foramen & the nasopalatine canal length are higher in men than women. The antero-posterior diameter of the nasal foramen, the medio-lateral diameter of the IF and the NPC increase with aging.

Research Authors
Mayada Ghallab El-Saadi Abdelaal Mohamed Fouad Edrees Mahmoud Ahmed Mizar Ibrahim Hammad Ibrahim Zein Abdou Shatat
Research Date
Research Department
Research Journal
African Journal of Biological Science
Research Publisher
African Journal of Biological Science
Research Rank
International
Research Vol
6
Research Website
https://www.afjbs.com/issue-content/assessment-of-nasopalatine-canal-anatomic-variations-using-cone-beam-computed-tomography-in-a-sample-of-the-egyptian-population-1498
Research Year
2024

Evaluation of Immediate Versus Delayed Implant Insertion with Flapless Piezotome Ridge Splitting for Rehabilitation of Patients with Narrow Alveolar Ridge

Research Abstract

ABSTRACT

Aim: The aim of this study was to evaluate the immediate implant placement versus delayed implant placement 3 months later of the splitting of thin alveolar bone sites using flapless crest splitting technique.

Subjects and Methods: This study was designed as a prospective clinical trial of 35 implants over 8 patients with 16 alveolar splitting sites. Eight sites were splitted and immediately implanted and submitted to group I, the another eight sites were splitted and implanted after 3 months they were submitted to group II, After alveolar ridge spiltting both groups were grafted via xenografts and covered with collagen membranes for guided bonr regeneration (GTR). For both groups we clinically assessed insertion torque, Implant stability quotient (ISQ) and radiographically horizontal bone gain and bone density at 3 intervals postoperatively, 3 and 6 months.

Results: The mean ISQ and insertion torque ± SD in group II was higher than group I. Group I showed a higher increase in bone gain than group II.

Conclusion: Immediate implantation after piezotome ridge splitting can be a useful procedure in ridges which have low bone quality and a thin cortex. Delayed implantation after piezotome ridge splitting is recommended when the initial stability of the implants is predicted to be poor. Both techniques using piezotome alveolar ridge splitting are effective in avoiding adjacent nerve injury.

Research Authors
Ahmed Gamal A. Kasim*1, Ashraf Abdelfattah1, Hosam El-Dein M. Ali1, Mohamed Mahgob Al-Ashmawy1, Abdel Aziz Baiomy Abdullah1, Zein Abdou Shatat 2 Mohamed Ashraf Abdel Fattah3
Research Date
Research Department
Research Journal
AL-AZHAR Assiut Dental Journal
Research Pages
131:140
Research Publisher
AL-AZHAR Assiut Dental Journal
Research Rank
Local
Research Vol
7
Research Website
https://aadj.journals.ekb.eg/article_356562.html
Research Year
2024

Computed Guided Prolotherapy Versus Conventional Prolotherapy in The Treatment of TMJ Internal Derangement

Research Abstract

ABSTRACT

Aim: This study was conducted to compare Computed guided arthrocentesis with conventional arthrocentesis followed by I-PRF prolotherapy in the treatment of TMJ internal derangement.

Subjects and methods: the study was carried out on 20 patients divided into two groups: Group I, patients underwent arthrocentesis followed by I-PRF injection using conventional TMJ injection technique with the aid of facial anatomical landmarks. Group II, patients underwent arthrocentesis followed by I-PRF injection using a CT-guided 3D printed surgical guide. Pain scores measured and MIO, preoperatively, immediately after the procedures, 1 week, 1 month, and 3 months. MRI was made 1 week and 3 months after the procedures. The number of attempts of needle insertions of 1st & 2nd needle (Right -Left) were assessed and the Time of operation and pain during the operation were assessed. Results: a significant decrease in pain during procedures, immediately post-operative, 1 week and 1 month post-operative, number of insertions and relocation of the needles in each joint, and time of the procedures in the guided arthrocentesis group compared to the conventional arthrocentesis group. On the other hand, there was no significant difference between both groups in MIO, preoperative pain after 3 months.

Conclusion: Digital arthrocentesis and prolotherapy of TMJ showed superiority and could replace the current conventional and prolotherapy types. Intra-articular PRF injection after arthrocentesis is an effective treatment method for the pain relief of TMJ internal derangements.

Research Authors
Zahran Arafat Ahmed Arafat1 , Abdelaziz Baiomy Abdullah*1, Ahmed Omar Makhlouf 1, Zein Abdou Shatat2
Research Date
Research Department
Research Journal
AL-AZHAR Assiut Dental Journal
Research Pages
85:93
Research Publisher
AL-AZHAR Assiut Dental Journal
Research Rank
Local
Research Vol
7
Research Website
https://aadj.journals.ekb.eg/article_356551.html
Research Year
2024

Prevalence of impacted third molars among different sagittal skeletal relationships in Upper Egyptian patients

Research Abstract

ABSTRACT

Aim: Our investigation aimed to evaluate the prevalence and patterns of impacted third molars
in a sample of Upper Egyptian patients and explore their association with different sagittal skeletal
relationships.

Materials and methods: A total of 352 pre-treatment panoramic radiographs (OPGs) and lateral
cephalograms were retrospectively reviewed. The patients, aged 18 to 40 years, were classified into
three skeletal groups based on the ANB angle. The number and angular position of impacted third
molars were assessed. We used Winter’s classification to find out impacted third molars angulation.

Results: Compared to Class I and Class III, the results disclosed a higher prevalence of third
molar impaction in Class II malocclusions. Additionally, Class II individuals exhibited a higher
prevalence of mesioangular and distoangular impactions, while Class III patients showed a greater
tendency for horizontal impactions in the mandible. Vertical impactions were more common in
Class II individuals. Furthermore, gender differences were observed, with females exhibiting
a higher percentage of impacted molars across all skeletal classes.

Conclusion: Class II malocclusions had higher mesioangular and distoangular impaction rates,
while Class III malocclusions were prone to mandibular horizontal impactions. Gender-related
differences showed females had a higher incidence of impacted molars across skeletal classes.
Understanding the link between skeletal class and third molar impactions is vital for improved
orthodontic planning.

Research Authors
Ahmed A.M. Abdelaziz* , Zein Abdou Shatat** , and Ahmed I. Abdul-Aziz*
Research Date
Research Department
Research Journal
Egyptian Dental Journal
Research Pages
27-33
Research Publisher
Egyptian Dental Journal
Research Rank
Local
Research Vol
70
Research Website
https://edj.journals.ekb.eg/article_332249.html
Research Year
2024

Clear aligners versus fixed orthodontic appliance on the occurrence of external root resorption in upper teeth; Cone-beam study

Research Abstract

ABSTRACT

Objective: To compare with the aid of cone beam CT the effect of treatment with clear aligner versus fixed orthodontic appliances on the external root resorption in upper teeth.

Patients and Methods: Fourteen individuals, aged between 15 and 25, took part in the study. Research randomization was used to assign patients who satisfied the inclusion criteria at random to the aligner and fixed groups.

Results: There were statistical significant differences in root volume and linear measurements of both groups (Paired t-tests were used between T0 and T1). Independent t-tests were used to compare the mean changes of root volumes and linear measurements between the two groups).

Conclusion: There is a significant root resorption in both clear aligner and fixed orthodontic appliance groups. The difference between both groups was statistically insignificant.

Research Authors
Ibrahim Saad Abd El-Ghafar *, Esmail Kamal Hewy Raslan*, Ahmed Mohamed Kilany*, Ahmed Mahmoud Ahmed Ali*, Mahmoud Mohamed Salah Eldin*, Zein Abdou Shatat*, Sara Elkabbany*, Mohamed Mohamed Ali *, Ahmed Shehata Ammar *, yasser Elsayed Hassouna
Research Date
Research Department
Research Journal
European Chemical Bulletin
Research Pages
14030-14041
Research Publisher
European Chemical Bulletin
Research Rank
Local
Research Website
https://www.researchgate.net/publication/374849422_Clear_aligners_versus_fixed_orthodontic_appliance_on_the_occurrence_of_external_root_resorption_in_upper_teeth_Cone-beam_study
Research Year
2023

Call for Entries: Faculty of Commerce Science Film Competition

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The Scientific Committee at the Faculty of Commerce announces a scientific competition titled "Cinema of Science."

Competition Guidelines:

  • Films must be between 10 and 15 minutes long.
  • The scientific film idea must be original and not previously presented.
  • Films must be submitted on a flash drive and will be returned after the screening.
  • Competition Details:

  • The competition will take place in the Activities Hall at the Faculty of Commerce's Student Affairs Administration.
  • The competition will be held from 10:00 AM to 1:00 PM.
  • Prizes:

  • Valuable cash prizes will be awarded to the top four winners (two male, two female).
  • All participants will receive certificates of participation.
  • Registration:

    Interested participants should register with the faculty's scientific activity coordinator.

 

Call for Registration: 43rd Scouting and 29th Guiding Courses

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The Scouting and Public Service Unit at the Central Youth Welfare Administration announces the organization of the 43rd Scouting and 29th Guiding Courses for the university's scouts and guides.

Dates: Thursday, November 21, 2024, to Saturday, December 7, 2024

Location: The university's permanent scouting camp

Interested students should register with the coordinator of the Scouting and Public Service Unit at the Faculty of Dentistry's Youth Welfare Administration.

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